| 1 | Thrivent Financial for Lutherans Minneapolis, MN | Minnesota | $118.0B | $11.8B |
| 2 | Kaiser Foundation Hospitals Oakland, CA | California | $87.4B | $38.2B |
| 3 | Lilly Endowment INC Indianapolis, IN | Indiana | $79.9B | $0 |
| 4 | Gates Foundation Seattle, WA | Washington | $78.7B | $0 |
| 5 | Gates Foundation Trust Kirkland, WA | Washington | $77.6B | $0 |
| 6 | President and Fellows of Harvard College Cambridge, MA | Massachusetts | $74.4B | $7.7B |
| 7 | Fidelity Investments Charitable Gift Fund Boston, MA | Massachusetts | $66.8B | $19.0B |
| 8 | The Board of Trustees of the Leland Stanford Junior University Stanford, CA | California | $63.3B | $9.5B |
| 9 | Uaw Retiree Medical Benefits TR Detroit, MI | Michigan | $62.9B | $3.5B |
| 10 | Chi Nebraska Omaha, NE | Nebraska | $61.0B | $0 |
| 11 | State Chartered Credit Unions INC Raleigh, NC | North Carolina | $56.4B | $2.6B |
| 12 | Yale University New Haven, CT | Connecticut | $55.2B | $6.8B |
| 13 | Harvard Management Private Equity Corporation Boston, MA | Massachusetts | $49.2B | $2.1B |
| 14 | Princeton University Princeton, NJ | New Jersey | $42.8B | $3.1B |
| 15 | National Philanthropic TR Jenkintown, PA | Pennsylvania | $42.2B | $15.9B |
| 16 | Donor Advised Charitable Giving San Francisco, CA | California | $41.1B | $9.7B |
| 17 | Massachusetts Institute of Technology Cambridge, MA | Massachusetts | $39.9B | $5.9B |
| 18 | National Rural Utilities Cooperative Finance Corp. Dulles, VA | Virginia | $38.3B | $2.1B |
| 19 | Trustees of the University of Pennsylvania Philadelphia, PA | Pennsylvania | $34.0B | $10.7B |
| 20 | Kaiser Foundation Health Plan INC Oakland, CA | California | $33.5B | $82.5B |
| 21 | Howard Hughes Medical Institute Chevy Chase, MD | Maryland | $29.5B | $2.0B |
| 22 | Mass General Brigham Incorporated and Affiliates Group RTN Somerville, MA | Massachusetts | $28.3B | $23.5B |
| 23 | University of Notre Dame du Lac Notre Dame, IN | Indiana | $26.7B | $3.3B |
| 24 | Mayo Clinic Rochester, MN | Minnesota | $26.7B | $7.9B |
| 25 | Cleveland Clinic Foundation Independence, OH | Ohio | $26.5B | $17.2B |
| 26 | Trustees of Columbia University New York, NY | New York | $24.8B | $7.3B |
| 27 | Ascension Health Alliance Saint Louis, MO | Missouri | $24.0B | $2.4B |
| 28 | Advocate Health and Hospitals Corporation Downers Grove, IL | Illinois | $23.8B | $7.8B |
| 29 | Milton Hershey School & School Trust Hershey, PA | Pennsylvania | $23.4B | $814.0M |
| 30 | Johns Hopkins University Baltimore, MD | Maryland | $23.0B | $10.5B |
| 31 | Michigan Catastrophic Claims Association U S Livonia, MI | Michigan | $22.4B | $1.8B |
| 32 | Emory University Atlanta, GA | Georgia | $22.2B | $7.3B |
| 33 | Vanguard Charitable Endowment Program Malvern, PA | Pennsylvania | $22.2B | $6.4B |
| 34 | The New York and Presbyterian Hospital New York, NY | New York | $21.9B | $10.7B |
| 35 | Duke University Durham, NC | North Carolina | $21.2B | $4.5B |
| 36 | New York University New York, NY | New York | $21.1B | $11.6B |
| 37 | Washington University St. Louis, MO | Missouri | $20.5B | $5.2B |
| 38 | The Golden 1 Credit Union Sacramento, CA | California | $19.6B | $989.7M |
| 39 | Alliant Credit Union Chicago, IL | Illinois | $19.5B | $1.3B |
| 40 | Northwestern University Evanston, IL | Illinois | $19.2B | $4.2B |
| 41 | Dignity Health San Francisco, CA | California | $18.8B | $11.3B |
| 42 | Ihc Health Services INC Salt Lake Cty, UT | Utah | $18.7B | $10.7B |
| 43 | Cornell University Ithaca, NY | New York | $18.6B | $6.6B |
| 44 | Modern Woodmen of America Rock Island, IL | Illinois | $18.2B | $1.9B |
| 45 | Mayo Clinic Group Return Rochester, MN | Minnesota | $17.9B | $14.9B |
| 46 | Suncoast Credit Union Tampa, FL | Florida | $17.8B | $1.1B |
| 47 | Banner Health Phoenix, AZ | Arizona | $17.7B | $10.8B |
| 48 | Ford Foundation New York, NY | New York | $17.5B | $0 |
| 49 | The Cleveland Clinic Foundation Cleveland, OH | Ohio | $17.4B | $9.7B |
| 50 | Central States Southeast & Southwest Areas Health & Welfare F Chicago, IL | Illinois | $16.6B | $5.5B |
| 51 | Mgb Pooled Holdings LLC Somerville, MA | Massachusetts | $16.2B | $892.1M |
| 52 | Trinity Health Corporation Livonia, MI | Michigan | $16.2B | $2.9B |
| 53 | Baycare Health Systems INC Clearwater, FL | Florida | $16.0B | $1.6B |
| 54 | Memorial Sloan-kettering Cancer Center New York, NY | New York | $15.5B | $8.5B |
| 55 | Commonspirit Health Operating Investment Pool LLC San Francisco, CA | California | $15.3B | $584.5M |
| 56 | Northwestern Memorial Healthcare Chicago, IL | Illinois | $15.2B | $2.3B |
| 57 | University of Southern California Los Angeles, CA | California | $15.1B | $5.6B |
| 58 | University of Chicago Chicago, IL | Illinois | $15.0B | $4.9B |
| 59 | University of Virginia Investment Management Company Charlottesvle, VA | Virginia | $14.6B | $912.3M |
| 60 | Novant Health INC Winston Salem, NC | North Carolina | $14.6B | $6.5B |
| 61 | Credit Unions Chartered in the State of Michigan Grand Rapids, MI | Michigan | $14.5B | $829.4M |
| 62 | Bon Secours Mercy Health INC Blue Ash, OH | Ohio | $14.4B | $11.5B |
| 63 | William & Flora Hewlett Foundation Menlo Park, CA | California | $14.2B | $0 |
| 64 | Northwestern Memorial Healthcare Chicago, IL | Illinois | $14.2B | $10.1B |
| 65 | Adventist Health System Sunbelt INC Altamonte Spg, FL | Florida | $14.1B | $8.3B |
| 66 | State Chartered Credit Unions in Florida Jacksonville, FL | Florida | $14.0B | $886.1M |
| 67 | Vanderbilt University Nashville, TN | Tennessee | $13.8B | $2.6B |
| 68 | Memorial Hermann Health System Houston, TX | Texas | $13.7B | $8.5B |
| 69 | Robert Wood Johnson Foundation Princeton, NJ | New Jersey | $13.4B | $0 |
| 70 | AARP Washington, DC | District of Columbia | $13.1B | $11.0B |
| 71 | J Paul Getty Trust Los Angeles, CA | California | $13.0B | $0 |
| 72 | Indiana University Health INC Indianapolis, IN | Indiana | $12.8B | $6.1B |
| 73 | Gs Donor Advised Philanthropy Fund for Wealth Management INC New York, NY | New York | $12.7B | $6.6B |
| 74 | Chancellor Masters and Scholars of the University of Cambridge New York, NY | New York | $12.6B | $3.1B |
| 75 | Adventist Health System Sunbelt Healthcare Corporation Altamonte Spg, FL | Florida | $12.5B | $3.2B |
| 76 | Cedars-sinai Medical Center W Hollywood, CA | California | $12.4B | $5.3B |
| 77 | Hudson East River Systems LLC New York, NY | New York | $12.4B | $156.9M |
| 78 | Silicon Valley Community Foundation Mountain View, CA | California | $12.3B | $4.9B |
| 79 | Trustees of the Estate of Bernice Pauahi Bishop Honolulu, HI | Hawaii | $12.2B | $588.8M |
| 80 | NYU Langone Hospitals New York, NY | New York | $12.1B | $9.5B |
| 81 | Stanford Health Care 227 Stanford, CA | California | $12.1B | $8.0B |
| 82 | Bloomberg Family Foundation INC New York, NY | New York | $12.1B | $0 |
| 83 | Trustees of Dartmouth College Hanover, NH | New Hampshire | $12.0B | $1.7B |
| 84 | Poudre Valley Health Care INC Fort Collins, CO | Colorado | $12.0B | $970.2M |
| 85 | Shriners Hospitals for Children Tampa, FL | Florida | $11.9B | $1.8B |
| 86 | The Methodist Hospital Houston, TX | Texas | $11.9B | $3.6B |
| 87 | St. Jude Childrens Research Hospital INC Memphis, TN | Tennessee | $11.7B | $2.0B |
| 88 | Gordon E and Betty I Moore Foundation Palo Alto, CA | California | $11.5B | $0 |
| 89 | Woodmen of the World Life Insurance Society Omaha, NE | Nebraska | $11.3B | $1.2B |
| 90 | Chancellor Masters & Scholars of the University of Oxford Cary, NC | North Carolina | $11.3B | $3.6B |
| 91 | UPMC Pittsburgh, PA | Pennsylvania | $11.2B | $24.3B |
| 92 | Foundation to Promote Open Society New York, NY | New York | $10.8B | $0 |
| 93 | William Marsh Rice University Houston, TX | Texas | $10.7B | $1.4B |
| 94 | University of Pittsburgh Pittsburgh, PA | Pennsylvania | $10.5B | $3.4B |
| 95 | Young Mens Christian Association Retirement Fund New York, NY | New York | $10.3B | $649.3M |
| 96 | Ohiohealth Corporation Grant Riverside Doctors Dublin Met Columbus, OH | Ohio | $10.2B | $5.1B |
| 97 | Sdg Impact Fund INC Cartersville, GA | Georgia | $10.1B | $13.6M |
| 98 | Childrens Hospital Medical Center Cincinnati, OH | Ohio | $10.0B | $3.4B |
| 99 | Brown University of Providence Providence, RI | Rhode Island | $10.0B | $1.6B |
| 100 | UPMC Pittsburgh, PA | Pennsylvania | $10.0B | $772.2M |