| 1 | West Texas Food Bank | Unclassified | $27.3M | $36.7M |
| 2 | Wood Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $26.4M | $45.4M |
| 3 | First Basin Credit Union | Unclassified | $19.8M | $309.9M |
| 4 | Odessa Country Club INC | Unclassified | $17.8M | $34.4M |
| 5 | Compass Academy Charter School INC | Education | $17.7M | $55.7M |
| 6 | Southwest Heritage Credit Union | Unclassified | $16.4M | $239.8M |
| 7 | Greater Opportunities of the Permian Basin INC | Human Services | $10.1M | $5.0M |
| 8 | Chc Community Care LLC | Health Care | $8.6M | $2.9M |
| 9 | Ellen Noel Art Museum of the Permian Basin | Arts, Culture & Humanities | $7.9M | $19.7M |
| 10 | Southwest 66 Credit Union | Unclassified | $6.9M | $105.2M |
| 11 | Medical Center Health System Foundation | Unclassified | $5.8M | $10.6M |
| 12 | Odessa College Foundation Incorporated | Education | $5.5M | $27.5M |
| 13 | Odessa Family YMCA | Human Services | $4.1M | $2.5M |
| 14 | West Texas Credit Union | Unclassified | $3.9M | $62.8M |
| 15 | Odessa Chamber of Commerce | Unclassified | $3.7M | $2.1M |
| 16 | Permian Basin Rehabilitation Center for Crippled Children and Adults | Health Care | $3.5M | $6.0M |
| 17 | Clover House INC | Unclassified | $3.1M | $2.0M |
| 18 | J C Ferguson Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.0M | $26.1M |
| 19 | Harmony Home Childrens Advocacy Center INC | Human Services | $2.8M | $2.3M |
| 20 | Crisis Center of West Texas | Unclassified | $2.5M | $6.7M |
| 21 | Boys & Girls Clubs of the Permian Basin INC | Youth Development | $2.4M | $351K |
| 22 | Veterans of Foreign Wars of the United States Dept of Texas | Unclassified | $2.3M | $389K |
| 23 | American Legion Earl S Bailey Post No 430 | Unclassified | $2.0M | $971K |
| 24 | Odessa Industrial Development Foundation | Unclassified | $2.0M | $19.4M |
| 25 | Ector County Isd Education Foundation INC | Education | $1.9M | $7.8M |
| 26 | International Association of Lions Clubs | Unclassified | $1.9M | $207K |
| 27 | Boys and Girls Club of Odessa INC | Youth Development | $1.8M | $3.1M |
| 28 | St. Johns Episcopal School of Odessa | Unclassified | $1.7M | $1.5M |
| 29 | Amvets | Unclassified | $1.6M | $328K |
| 30 | Sand Hills Hereford & Quarterhorse Show INC | Unclassified | $1.6M | $542K |
| 31 | United Way of Odessa INC | Philanthropy, Voluntarism & Grantmaking | $1.6M | $2.3M |
| 32 | Safari Club International Foundation | Animal-Related | $1.5M | $816K |
| 33 | The Heritage of Odessa Foundation | Unclassified | $1.5M | $825K |
| 34 | Permian Basin Regional Council on Alcohol and Drug Abuse | Mental Health & Crisis Intervention | $1.5M | $443K |
| 35 | Amvets | Unclassified | $1.4M | $28K |
| 36 | Lou Rosenberg Scholarship Fund | Unclassified | $1.4M | $90K |
| 37 | Meals on Wheels of Odessa Incorporated | Unclassified | $1.3M | $2.3M |
| 38 | Odessa Christian School INC | Education | $1.2M | $2.4M |
| 39 | Humane Society of Odessa | Community Improvement & Capacity Building | $997K | $1.2M |
| 40 | Odessa Employees Credit Union | Unclassified | $941K | $19.7M |
| 41 | Permian Basin First Priority INC | Religion-Related | $924K | $962K |
| 42 | Permian Basin Mission Center | Human Services | $913K | $2.2M |
| 43 | Odessa Council for the Arts & Humanities | Arts, Culture & Humanities | $820K | $234K |
| 44 | Odessa Day Nursery | Human Services | $816K | $934K |
| 45 | Montessori Middle School of Odessa | Education | $815K | $356K |
| 46 | First United Methodist Church of Odessa Foundation INC | Unclassified | $801K | $2.6M |
| 47 | Catholic Charities Community Services Odessa INC | Human Services | $794K | $2.3M |
| 48 | Saulsbury Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $769K | $2.7M |
| 49 | Permian Basin Fair & Exposition | Unclassified | $764K | $776K |
| 50 | Pink the Basin | Diseases, Disorders & Medical Disciplines | $755K | $1.3M |
| 51 | International Association of Lions Clubs | Unclassified | $728K | $115K |
| 52 | Arroyo Foundation | Philanthropy, Voluntarism & Grantmaking | $637K | $1.6M |
| 53 | Texas Motorized Trail Coalition INC | Recreation & Sports | $623K | $8.5M |
| 54 | Vrdur Foundation INC | Human Services | $603K | $603K |
| 55 | Pride Center West Texas | Human Services | $557K | $18K |
| 56 | Permian Basin Elite Volleyball Club INC | Recreation & Sports | $539K | $449K |
| 57 | Able Center for Independent Living | Human Services | $534K | $199K |
| 58 | Junior League of Odessa INC | Community Improvement & Capacity Building | $518K | $2.5M |
| 59 | West Texas Gifts of Hope INC | Health Care | $467K | $1.8M |
| 60 | Permian High School Band Boosters | Unclassified | $461K | $181K |
| 61 | Rig Dfw | Religion-Related | $447K | $34K |
| 62 | Casa of the Permian Basin Area INC | Civil Rights, Social Action & Advocacy | $441K | $325K |
| 63 | Nourishing the Nations | Food, Agriculture & Nutrition | $440K | $208K |
| 64 | People Pride INC | Education | $438K | $574K |
| 65 | Jesus House Odessa | Human Services | $417K | $633K |
| 66 | The Permian Football Booster Club | Education | $415K | $184K |
| 67 | Odessa Links INC | Human Services | $406K | $232K |
| 68 | Compass Athletic Booster Club | Education | $397K | $376K |
| 69 | Odessa Ector Parks Foundation INC | Philanthropy, Voluntarism & Grantmaking | $379K | $2.7M |
| 70 | Just Paws INC | Animal-Related | $374K | $240K |
| 71 | Permian Basin Oil Show INC | Unclassified | $367K | $2.5M |
| 72 | West Texas Hunting and Fishing Heritage Museum INC | Arts, Culture & Humanities | $359K | $1.5M |
| 73 | Compass Academy Education Foundation | Education | $321K | $548K |
| 74 | Amy Bell Sports Foundation INC | Recreation & Sports | $300K | $300K |
| 75 | Compass Academy Parent-teacher Organization | Education | $293K | $162K |
| 76 | West Odessa Volunteer Fire Department | Unclassified | $291K | $2.1M |
| 77 | Odessa Crime Stoppers Incorporated | Unclassified | $287K | $115K |
| 78 | South Ector County Volunteer Fire Department | Public Safety, Disaster Preparedness & Relief | $277K | $297K |
| 79 | Odessa Chuck Wagon Gang INC | Community Improvement & Capacity Building | $230K | $103K |
| 80 | Odessa Christmas in Action INC | Unclassified | $225K | $534K |
| 81 | White Pool House Friends | Arts, Culture & Humanities | $211K | $784K |
| 82 | Odessa High School Showgirls Booster Club | Education | $209K | $34K |
| 83 | Odessa Lodge No 1701 Loyal Order Moose Incorporated | Mutual & Membership Benefit | $204K | $387K |
| 84 | Family Promise of Odessa INC | Unclassified | $197K | $343K |
| 85 | Live Like Rylee Foundation | Diseases, Disorders & Medical Disciplines | $196K | $380K |
| 86 | Odessa Permian High School Baseball Booster Club INC | Education | $190K | $128K |
| 87 | Odessa High School Band and Orchestra Booster Club | Education | $186K | $46K |
| 88 | Revolution Fc | Youth Development | $184K | $54K |
| 89 | Mojo Choir | Education | $183K | $71K |
| 90 | Odessa Symphony Guild | Arts, Culture & Humanities | $172K | $284K |
| 91 | T S C E C INC | Recreation & Sports | $162K | $24K |
| 92 | Ernest Cecil Filio Foundation Incorporated | Mental Health & Crisis Intervention | $161K | $207K |
| 93 | Panther Paws Booster Club | Unclassified | $160K | $159K |
| 94 | 1911 Foundation | Philanthropy, Voluntarism & Grantmaking | $160K | $50K |
| 95 | Medical Center Health System | Health Care | $156K | $1.6M |
| 96 | Odessa Affordable Housing INC | Housing & Shelter | $155K | $401K |
| 97 | Crystal Ball Foundation of Odessa | Health Care | $146K | $164K |
| 98 | Odessa High School Broncho Booster Club | Education | $144K | $52K |
| 99 | Creation Calendar Research Association | Unclassified | $136K | $290K |
| 100 | Fada Mission International INC | International, Foreign Affairs & National Security | $133K | $41K |