| 1 | South Central Power Company | Unclassified | $391.9M | $903.7M |
| 2 | Fairfield Medical Center | Health Care | $372.6M | $281.9M |
| 3 | Fairfield Healthcare Professionals INC | Unclassified | $37.4M | $16.5M |
| 4 | Fairhope Hospice & Palliative Care INC | Unclassified | $15.3M | $14.2M |
| 5 | Stream and Wetlands Foundation | Unclassified | $14.2M | $51.8M |
| 6 | Community Action Program Commission of the Lancaster-fairfield County | Community Improvement & Capacity Building | $13.5M | $9.9M |
| 7 | Fairfield Community Health Center | Health Care | $7.8M | $9.4M |
| 8 | Fairfield County Foundation | Philanthropy, Voluntarism & Grantmaking | $7.7M | $76.4M |
| 9 | New Horizons Mental Health Services INC | Mental Health & Crisis Intervention | $6.5M | $2.7M |
| 10 | Meals on Wheels Older Adult Alternatives of Fairfield County | Human Services | $6.1M | $5.6M |
| 11 | Mid-ohio Psychological Services INC | Unclassified | $3.5M | $1.8M |
| 12 | Veterans of Foreign Wars of the United States Department of Ohio | Unclassified | $3.3M | $272K |
| 13 | Family YMCA of Lancaster & Fairfield County | Human Services | $3.2M | $5.5M |
| 14 | Geneva Hills Group INC | Recreation & Sports | $2.9M | $1.1M |
| 15 | Fairfield County Agricultural Society | Food, Agriculture & Nutrition | $2.2M | $1.6M |
| 16 | Fairfield Area Humane Society | Animal-Related | $2.2M | $2.4M |
| 17 | Lancaster Festival INC | Arts, Culture & Humanities | $2.1M | $1.1M |
| 18 | Veterans of Foreign Wars of the United States Department of Ohio | Unclassified | $2.0M | $830K |
| 19 | Fairfield Medical Center Foundation | Philanthropy, Voluntarism & Grantmaking | $2.0M | $3.3M |
| 20 | Maywood Mission | Human Services | $1.8M | $2.4M |
| 21 | Fairfield Center for Disabilities and Cerebral Palsy INC | Unclassified | $1.8M | $1.8M |
| 22 | Lancaster Athletic Booster Club | Youth Development | $1.8M | $167K |
| 23 | Lancaster Lodge 955 Loyal Order of Moose | Unclassified | $1.7M | $2.0M |
| 24 | West After School Center | Education | $1.6M | $1.7M |
| 25 | United Way of Fairfield County | Philanthropy, Voluntarism & Grantmaking | $1.6M | $2.1M |
| 26 | The Recovery Center | Mental Health & Crisis Intervention | $1.4M | $1.0M |
| 27 | Lancaster Camp Meeting & Assembly Assn. | Religion-Related | $1.2M | $2.1M |
| 28 | Knights of Columbus | Unclassified | $1.2M | $52K |
| 29 | Fox Foundation INC | Unclassified | $1.1M | $2.1M |
| 30 | Information & Referral of Fairfield County | Mental Health & Crisis Intervention | $1.0M | $1.1M |
| 31 | Harcum House | Human Services | $1.0M | $1.4M |
| 32 | The Lighthouse | Human Services | $1.0M | $787K |
| 33 | Decorative Arts Center of Ohio | Arts, Culture & Humanities | $932K | $3.1M |
| 34 | Lancaster Police Athletic League | Youth Development | $895K | $255K |
| 35 | Lancaster Fresh Market INC | Food, Agriculture & Nutrition | $819K | $397K |
| 36 | Dragonfly Dreams Housing INC | Housing & Shelter | $818K | $2.9M |
| 37 | Fraternal Order of Eagles | Unclassified | $754K | $839K |
| 38 | Bottoms Up Diaper Drive | Human Services | $719K | $454K |
| 39 | 40 Et 8 INC Voiture 498 | Unclassified | $687K | $194K |
| 40 | Fairfield Industries INC | Employment | $673K | $916K |
| 41 | South Central Power Company Foundation | Education | $667K | $467K |
| 42 | Fairfield County Visitors & Convention Bureau INC | Unclassified | $662K | $457K |
| 43 | Connexion West | Human Services | $646K | $208K |
| 44 | Saint Vincent Depaul Society | Unclassified | $643K | $579K |
| 45 | American Legion | Unclassified | $525K | $506K |
| 46 | Big Brothers-big Sisters of Fairfield Co INC | Unclassified | $510K | $487K |
| 47 | Lancaster Fairfied County Chamber | Unclassified | $457K | $261K |
| 48 | Fairfield County Baseball Complex Association INC | Unclassified | $429K | $700K |
| 49 | Ohio Glass Museum | Arts, Culture & Humanities | $401K | $1.2M |
| 50 | Destination Downtown Lancaster INC | Arts, Culture & Humanities | $387K | $106K |
| 51 | Pine Lake Estates of Fairfield County INC | Unclassified | $360K | $713K |
| 52 | Amvets | Unclassified | $353K | $390K |
| 53 | Aha a Hands on Adventure a Childrens Museum INC | Arts, Culture & Humanities | $344K | $1.7M |
| 54 | Olive Dale Senior Citizens of Fairfield County Ohio | Human Services | $343K | $558K |
| 55 | Anlee Residential Services INC | Human Services | $332K | $52K |
| 56 | Fairfield Mental Health Consumer Group INC | Human Services | $322K | $133K |
| 57 | Southeastern Ohio Center for Independent Living INC | Human Services | $320K | $87K |
| 58 | Fairfield County Heritage Association | Arts, Culture & Humanities | $320K | $2.5M |
| 59 | Fairfield 33 Development Alliance | Mutual & Membership Benefit | $313K | $178K |
| 60 | Creed House INC | Human Services | $262K | $131K |
| 61 | Kelley Family Foundation | Philanthropy, Voluntarism & Grantmaking | $249K | $900K |
| 62 | Lancaster Fairfield County Charity Newsies INC | Human Services | $246K | $410K |
| 63 | Lancaster Soap Box Derby INC | Recreation & Sports | $242K | $231K |
| 64 | E B Evaluations INC | Mental Health & Crisis Intervention | $234K | $55K |
| 65 | Environmental Education Council of Ohio Incorporated | Environment | $217K | $218K |
| 66 | Lancaster Board of Realtors INC | Unclassified | $212K | $121K |
| 67 | Lancaster Select Soccer Association INC | Recreation & Sports | $212K | $220K |
| 68 | Hocking Valley Gymnastics Boosters Organization INC | Recreation & Sports | $202K | $102K |
| 69 | Amvets | Unclassified | $199K | $170K |
| 70 | International Compassion Alliance | Human Services | $196K | $105K |
| 71 | Foundation Dinners | Food, Agriculture & Nutrition | $160K | $274K |
| 72 | Foundation Shelters | Housing & Shelter | $156K | $219K |
| 73 | Lancaster Band Boosters INC | Unclassified | $150K | $628K |
| 74 | Outreach for Youth | Religion-Related | $127K | $1.1M |
| 75 | Lancaster Eagles Forest Rose Aerie 2120 Charity and Scholarship Fund | Philanthropy, Voluntarism & Grantmaking | $120K | $116K |
| 76 | Angel Works Foundation | Human Services | $120K | $23K |
| 77 | Fairfield Union Athletic Booster Club | Education | $119K | $46K |
| 78 | Grace Haven Ministries | Crime & Legal-Related | $117K | $508K |
| 79 | International Association of Fire Fighters | Unclassified | $114K | $96K |
| 80 | Rise Up Youth Theatre | Arts, Culture & Humanities | $109K | $25K |
| 81 | Montessori Society of Lancaster INC | Education | $109K | $118K |
| 82 | Lancaster Education Association Lea | Unclassified | $107K | $185K |
| 83 | Fraternal Order of Police | Unclassified | $100K | $22K |
| 84 | Lancaster Golden Gales Touchdown Club | Education | $99K | $27K |
| 85 | Orchard Place Housing Corporation | Human Services | $96K | $226K |
| 86 | Downtown Lancaster Special Improvement District INC | Environment | $96K | $35K |
| 87 | United States Bowling Congress INC | Recreation & Sports | $95K | $15K |
| 88 | Little League Baseball INC | Recreation & Sports | $95K | $28K |
| 89 | Lancaster-fairfield County 4TH of July Committee INC | Unclassified | $91K | $50K |
| 90 | Kiwanis International INC | Unclassified | $90K | $361K |
| 91 | Living Again Ministries INC | Housing & Shelter | $89K | $41K |
| 92 | Fairfield Medical Center Twig Two | Human Services | $85K | $52K |
| 93 | Inter Lake Yachtsmens Fund | Unclassified | $85K | $829K |
| 94 | Bertha V Wilson Deceased | Philanthropy, Voluntarism & Grantmaking | $82K | $866K |
| 95 | Proarteohio Vocal Ensemble | Unclassified | $81K | $25K |
| 96 | Farm House Fraternity INC | Unclassified | $65K | $245K |
| 97 | Ault Manor INC | Housing & Shelter | $62K | $177K |
| 98 | Gro Ecowellness | Mental Health & Crisis Intervention | $58K | $32K |
| 99 | Cherry Gardens INC | Human Services | $57K | $71K |
| 100 | Friends of the Lancaster Parks and Recreation | Unclassified | $55K | $91K |