| 1 | Cleveland Clinic Foundation | Health Care | $20.0B | $26.5B |
| 2 | First Catholic Slovak Union of the United States & Canada | Unclassified | $109.0M | $587.5M |
| 3 | Brotherhood of Locomotive Engineers and Trainmen | Unclassified | $55.7M | $23.3M |
| 4 | Brotherhood of Locomotive Engineers & Trainmen | Employment | $20.5M | $37.3M |
| 5 | American Journey Financial Life | Unclassified | $18.0M | $221.5M |
| 6 | In His Steps Foundation | Philanthropy, Voluntarism & Grantmaking | $13.1M | $45.4M |
| 7 | Blet Disability & Welfare Benefit Trust Fund | Mutual & Membership Benefit | $10.3M | $20.4M |
| 8 | Precision Metal Forming Association | Unclassified | $9.8M | $19.0M |
| 9 | Cornerstone of Hope INC | Human Services | $8.0M | $8.9M |
| 10 | Smart Discipline Income Protection Program | Mutual & Membership Benefit | $6.8M | $25.2M |
| 11 | The Fedeli Family Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $5.5M | $17.0M |
| 12 | Forging Industry Association | Unclassified | $5.1M | $6.8M |
| 13 | Aealas of Ohio INC | Unclassified | $5.0M | $4.4M |
| 14 | Health Action Council Ohio | Unclassified | $4.6M | $9.1M |
| 15 | Smart Transportation Division Staff Retiree Health Fund | Mutual & Membership Benefit | $4.2M | $6.4M |
| 16 | Ohio Alliance to End Sexual Violence | Mental Health & Crisis Intervention | $4.2M | $1.5M |
| 17 | Taleris Credit Union INC | Unclassified | $3.8M | $64.2M |
| 18 | Turn 2 Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.4M | $542K |
| 19 | Manufacturing Works | Unclassified | $3.2M | $954K |
| 20 | International Association of Business Intermediaries INC | Unclassified | $2.8M | $3.6M |
| 21 | The Covia Foundation | Philanthropy, Voluntarism & Grantmaking | $2.8M | $10.8M |
| 22 | Industrial Fasteners Institute | Unclassified | $2.7M | $3.2M |
| 23 | Milton a & Charlotte R Kramer Charitable Foundation | Unclassified | $2.5M | $6.2M |
| 24 | Ralph T & Esther Warburton Foundation | Unclassified | $2.3M | $2.1M |
| 25 | Forging Industry Educational and Research Foundation | Community Improvement & Capacity Building | $2.2M | $3.6M |
| 26 | Hba Charitable and Education Foundation | Environment | $2.2M | $1.4M |
| 27 | Ohio Junior Hockey Association INC | Unclassified | $2.1M | $1.3M |
| 28 | St. Charles Borromeo Educationalfoundation | Religion-Related | $2.0M | $18.1M |
| 29 | National Association of Letter Carriers | Unclassified | $1.8M | $1.1M |
| 30 | Brees Dream Foundation | Philanthropy, Voluntarism & Grantmaking | $1.7M | $733K |
| 31 | S K Wellman Foundation | Unclassified | $1.6M | $3.5M |
| 32 | Pathfinder Career Academy of Ohio | Education | $1.3M | $200K |
| 33 | Frg Family Fund INC | Human Services | $1.3M | $115K |
| 34 | Hart Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.3M | $2.3M |
| 35 | Central School of Practical Nursing INC | Education | $1.2M | $1.2M |
| 36 | Mechanical Contracting Industry Fund of Cleveland Ohio | Unclassified | $1.2M | $3.5M |
| 37 | Kidney Foundation of Ohio INC | Diseases, Disorders & Medical Disciplines | $985K | $3.5M |
| 38 | Cleveland Builds | Education | $977K | $315K |
| 39 | Mercy Development Foundation | Unclassified | $946K | $2.8M |
| 40 | Precision Metalforming Association Educational Foundation | Science & Technology | $934K | $2.3M |
| 41 | 379 Ohio Teamsters Credit Union INC | Unclassified | $929K | $16.9M |
| 42 | Peyback Foundation INC | Philanthropy, Voluntarism & Grantmaking | $879K | $4.9M |
| 43 | Home Builders Association of Greater Cleveland | Unclassified | $862K | $435K |
| 44 | Down Syndrome Association of Northeast Ohio | Unclassified | $846K | $964K |
| 45 | Hope Meadows Foundation | Unclassified | $843K | $903K |
| 46 | Rec2connect Foundation | Human Services | $830K | $231K |
| 47 | Construction Employers Association | Unclassified | $755K | $5.0M |
| 48 | Kenneth W Scott Foundation | Philanthropy, Voluntarism & Grantmaking | $738K | $10.5M |
| 49 | Gregory and Lyn Kurtz Foundation | Philanthropy, Voluntarism & Grantmaking | $689K | $2.1M |
| 50 | Phi Sigma Rho National Sorority | Education | $663K | $640K |
| 51 | School Ministries | Education | $621K | $478K |
| 52 | Workers Justice Committee | Employment | $609K | $314K |
| 53 | Brotherhood of Locomotive Engineers Building Association | Unclassified | $578K | $6.8M |
| 54 | Motiv8 Foundation INC | Human Services | $575K | $889K |
| 55 | Josiahs House INC | Mental Health & Crisis Intervention | $556K | $168K |
| 56 | Im in Ministry | Religion-Related | $447K | $340K |
| 57 | Dance Up | Arts, Culture & Humanities | $424K | $113K |
| 58 | Academy of Medicine of Cleveland | Unclassified | $412K | $555K |
| 59 | Cleveland Association of Building Owners and Managers | Unclassified | $400K | $284K |
| 60 | Luciano Family Foundation | Philanthropy, Voluntarism & Grantmaking | $334K | $645K |
| 61 | Legacies Empowered | Human Services | $291K | $20K |
| 62 | Cleveland Automobile Club Orphans Outing Fund | Unclassified | $287K | $1.8M |
| 63 | P a L S for Healing | Mental Health & Crisis Intervention | $274K | $231K |
| 64 | Allison Rose Foundation | Education | $271K | $321K |
| 65 | James Blake Foundation INC | Human Services | $247K | $169K |
| 66 | American Association of University Professors | Unclassified | $239K | $704K |
| 67 | Fraternal Order of Police | Unclassified | $237K | $779K |
| 68 | Ohio Association of Pupil Service Administrators | Community Improvement & Capacity Building | $234K | $105K |
| 69 | Love INC of Cuyahoga County | Human Services | $230K | $115K |
| 70 | Tomlinson Touching Lives Foundation | Philanthropy, Voluntarism & Grantmaking | $223K | $390K |
| 71 | Academy of Medicine Education Foundation | Health Care | $222K | $1.2M |
| 72 | 1ST and 10 Foundation | Philanthropy, Voluntarism & Grantmaking | $193K | $1.1M |
| 73 | Breast Cancer Fund of Ohio | Medical Research | $193K | $134K |
| 74 | Beyond the Challenge | Human Services | $188K | $86K |
| 75 | Michael Ann & Saquon Barkley Hope Foundation | Philanthropy, Voluntarism & Grantmaking | $168K | $353K |
| 76 | Star Camp | Recreation & Sports | $155K | $20K |
| 77 | Independence Primary School PTO | Education | $123K | $59K |
| 78 | Independence Athletic Booster Club | Recreation & Sports | $122K | $46K |
| 79 | Ralph R McVeen Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $109K | $1.1M |
| 80 | John B & Audrey J Odonnell Foundation | Philanthropy, Voluntarism & Grantmaking | $109K | $2.3M |
| 81 | Institute of Internal Auditors | Unclassified | $106K | $86K |
| 82 | Independence Kiwanis Foundation INC | Education | $95K | $97K |
| 83 | Zims Foundation INC | Philanthropy, Voluntarism & Grantmaking | $89K | $1.1M |
| 84 | Polonia Foundation of Ohio INC | Unclassified | $82K | $751K |
| 85 | Kidney Foundation of Ohio INC | Diseases, Disorders & Medical Disciplines | $78K | $166K |
| 86 | Conway Family Foundation | Philanthropy, Voluntarism & Grantmaking | $78K | $651K |
| 87 | Kohrs Family Foundation | Philanthropy, Voluntarism & Grantmaking | $77K | $1.2M |
| 88 | Cleveland Polka Association | Unclassified | $77K | $43K |
| 89 | Sae Services INC | Unclassified | $72K | $351K |
| 90 | Insurance Board of Northern Ohio INC | Community Improvement & Capacity Building | $65K | $43K |
| 91 | Independence Youth Football INC | Recreation & Sports | $65K | $10K |
| 92 | Leaderwithin INC | Religion-Related | $65K | $767 |
| 93 | Hildegard O Nehring Foundation | Philanthropy, Voluntarism & Grantmaking | $63K | $1.1M |
| 94 | Kidney Foundation of Ohio Real Estate Foundation | Philanthropy, Voluntarism & Grantmaking | $62K | $324K |
| 95 | Smart Td Disaster Relief Fund | Public Safety, Disaster Preparedness & Relief | $61K | $72K |
| 96 | Greater Cleveland School Superintendents Association | Education | $58K | $150K |
| 97 | Polish National Alliance of the United States of NA | Unclassified | $58K | $197K |
| 98 | Kurtz Foundation INC | Unclassified | $56K | $18K |
| 99 | National Longhouse Ltd | Youth Development | $49K | $99K |
| 100 | Society for Preservation & Encrgmnt of Barbershop Quartet Singing Amer | Unclassified | $43K | $27K |