| 1 | Bon Secours Mercy Health INC | Health Care | $11.5B | $14.4B |
| 2 | Matthew 25 Ministries INC | International, Foreign Affairs & National Security | $281.7M | $125.2M |
| 3 | Roper St. Francis Healthcare | Health Care | $259.9M | $2.4B |
| 4 | Healthspan Partners | Health Care | $180.8M | $2.3B |
| 5 | Council on Aging of Southwestern Ohio | Human Services | $129.0M | $31.7M |
| 6 | Bon Secours Mercy Health Foundation | Religion-Related | $90.5M | $436.9M |
| 7 | L and L Nippert Charitable Foundation INC | Unclassified | $47.2M | $59.3M |
| 8 | Girl Scouts of Western Ohio | Youth Development | $25.7M | $38.5M |
| 9 | Local Initiative for Excellence Foundation | Health Care | $18.8M | $32.8M |
| 10 | Tennis for Charity INC | Health Care | $17.0M | $15.7M |
| 11 | United Pet Fund | Animal-Related | $11.2M | $382K |
| 12 | Jewish Family Service of the Cincinnati Area | Human Services | $10.8M | $10.3M |
| 13 | Educational Theatre Association | Education | $8.9M | $5.5M |
| 14 | Educational Theatre Association | Arts, Culture & Humanities | $7.5M | $5.9M |
| 15 | Techsolve INC | Community Improvement & Capacity Building | $7.2M | $7.9M |
| 16 | Mental Health America of Northern Kentucky and Southwest Ohio INC | Mental Health & Crisis Intervention | $4.8M | $2.1M |
| 17 | Clement and Ann Buenger Foundation | Unclassified | $4.2M | $49.2M |
| 18 | Restavec Freedom Foundation | Unclassified | $3.0M | $5.6M |
| 19 | Interalliance of Greater Cincinnati | Youth Development | $2.1M | $499K |
| 20 | Halom House | Unclassified | $2.0M | $4.4M |
| 21 | Ursuline Foundation | Unclassified | $1.2M | $19.2M |
| 22 | Call of Love INC | Religion-Related | $1.1M | $1.9M |
| 23 | Hyman and Bessie Passman Family Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.0M | $2.3M |
| 24 | Operation Give Back | Unclassified | $1.0M | $444K |
| 25 | Cincinnati Eye Institute Foundation | Medical Research | $979K | $671K |
| 26 | Jerome S Glazer Foundation INC | Philanthropy, Voluntarism & Grantmaking | $698K | $3.8M |
| 27 | Lincoln W Pavey Educational Foundation | Education | $562K | $433K |
| 28 | Ohio River Foundation | Environment | $548K | $328K |
| 29 | Fatherhood Revisited | Youth Development | $482K | $635K |
| 30 | A Good Day Foundation | Philanthropy, Voluntarism & Grantmaking | $457K | $73K |
| 31 | Healthspan Integrated Care | Health Care | $439K | $15.2M |
| 32 | Frankel Family Charitable Trust | Unclassified | $409K | $4.4M |
| 33 | Queen City Angels | Community Improvement & Capacity Building | $396K | $29K |
| 34 | Educational Theatre Association Foundation | Unclassified | $390K | $1.3M |
| 35 | Academy of Medicine of Cincinnati | Unclassified | $373K | $246K |
| 36 | Jane Stotts Foundation | Philanthropy, Voluntarism & Grantmaking | $364K | $498K |
| 37 | Parkinson Community Fitness | Human Services | $285K | $152K |
| 38 | Laburnum Properties INC | Unclassified | $276K | $8.2M |
| 39 | Angels Watch | Animal-Related | $233K | $187K |
| 40 | Hope Restored India INC | International, Foreign Affairs & National Security | $229K | $46K |
| 41 | Infotrust Foundation | Community Improvement & Capacity Building | $212K | $9K |
| 42 | Creating Alternative Reason to Excel INC | Education | $197K | $84K |
| 43 | Soccer Assoc for Youth | Unclassified | $188K | $158K |
| 44 | Marty & Bob Jacobs Foundation | Mental Health & Crisis Intervention | $185K | $133K |
| 45 | From Fatherless to Fearless | Health Care | $170K | $64K |
| 46 | Dream House Homes INC | Housing & Shelter | $120K | $583K |
| 47 | Their Voice of Greater Cincinnati | Human Services | $115K | $35K |
| 48 | Ohio Association of Gerontology and Education | Diseases, Disorders & Medical Disciplines | $110K | $97K |
| 49 | Communicare Cares II INC | Health Care | $85K | $11K |
| 50 | Ballet and Books | Arts, Culture & Humanities | $80K | $86K |
| 51 | Queen City Wheels INC | Recreation & Sports | $73K | $51K |
| 52 | Maple Dale PTO | Education | $66K | $35K |
| 53 | Le Jeune Ballet National Co | Arts, Culture & Humanities | $59K | $64K |
| 54 | E H Greene Parent Teacher Organization | Education | $55K | $68K |
| 55 | Robert M McClure Memorial Scholarship Foundation | Philanthropy, Voluntarism & Grantmaking | $51K | $1K |
| 56 | Ankur Gujarati Samaji INC | Arts, Culture & Humanities | $50K | $262K |
| 57 | Association of Indian Physicians | Health Care | $48K | $79K |
| 58 | Pay It Forward Cincinnati | Human Services | $46K | $142K |
| 59 | Eyes Open International | Human Services | $41K | $20K |
| 60 | Blue Ash Sister City INC | Youth Development | $40K | $30K |
| 61 | American Legion | Unclassified | $27K | $186K |
| 62 | Frankel Family Foundation | Philanthropy, Voluntarism & Grantmaking | $12K | $347K |
| 63 | Association of Philippine Physicians of Greater Cincinnati | Unclassified | $10K | $47K |
| 64 | Bright Seed Foundation | Philanthropy, Voluntarism & Grantmaking | $8K | $94K |
| 65 | Blue Ash Fire Department House Fund | Public Safety, Disaster Preparedness & Relief | $1K | $1K |
| 66 | Four Winds Academy for the Healing and Arts Sciences | Education | $300 | $15K |
| 67 | Lifeway Health Initiative INC | Mental Health & Crisis Intervention | $1 | $171 |
| 68 | Schulte & Uhrig Foundation | Philanthropy, Voluntarism & Grantmaking | $1 | $27 |
| 69 | Vora Foundation | Philanthropy, Voluntarism & Grantmaking | $1 | $1 |
| 70 | Sycamore Alumni and Friends Association | Education | $0 | $0 |
| 71 | Saint Mary Hospital | Health Care | $0 | $0 |
| 72 | Bon Secours Health System of Nj INC | Health Care | $0 | $0 |
| 73 | Center for Jewish Learning and Living INC | Religion-Related | $0 | $0 |
| 74 | Chinese American Association of | Unclassified | $0 | $0 |
| 75 | Taekwondo Development Partners INC | Recreation & Sports | $0 | $0 |
| 76 | Ursuline Academy of Cincinnati | Unclassified | $0 | $0 |
| 77 | Blue Ash Civic League INC | Unclassified | $0 | $0 |
| 78 | Sycamore First Step Cooperative School | Unclassified | $0 | $0 |
| 79 | Eitz Chaim Yeshiva | Religion-Related | $0 | $0 |
| 80 | Service Association of Ohio INC | Unclassified | $0 | $0 |
| 81 | Engineers and Scientists Foundation of Cincinnati | Unclassified | $0 | $0 |
| 82 | Woodward Alumnal Endowment Fund | Unclassified | $0 | $0 |
| 83 | Sigma Phi Alpha Dental Hygiene Honor Society | Unclassified | $0 | $0 |
| 84 | Glory Baptist Church of Cincinnati | Religion-Related | $0 | $0 |
| 85 | Korean Central Presbyterian Church of Cincinnati | Unclassified | $0 | $0 |
| 86 | Werden-sampson Family Scholarship | Education | $0 | $0 |
| 87 | First Baptist Church Miamitown | Unclassified | $0 | $0 |
| 88 | United Spiritualists of the Christ Light | Unclassified | $0 | $0 |
| 89 | Messiah Community Church Ministries INC | Religion-Related | $0 | $0 |
| 90 | Faith Community Alliance of Greater Cincinnati | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 91 | Ohio Patient Network | Health Care | $0 | $0 |
| 92 | Society for Preservation & Encourmt of Barbershop Quartet Singing Amer | Unclassified | $0 | $0 |
| 93 | Miami Baptist Association | Unclassified | $0 | $0 |
| 94 | Hamilton County Municpal League | Community Improvement & Capacity Building | $0 | $0 |
| 95 | We Are the Future Foundation | Education | $0 | $0 |
| 96 | Black Sheep Foundation | Youth Development | $0 | $0 |
| 97 | Your Life Line Adult Care INC | Human Services | $0 | $0 |
| 98 | Future Achievers Academy Scs | Education | $0 | $0 |
| 99 | Hazelwood Helping Hands | Human Services | $0 | $0 |
| 100 | Assumption Village | Unclassified | $0 | $0 |