| 1 | Franciscan Alliance INC | Health Care | $3.8B | $6.3B |
| 2 | Saint Joseph Regional Medical Center-south Bend Campus INC | Health Care | $388.0M | $1.3B |
| 3 | Hills Insurance Company INC | Mutual & Membership Benefit | $184.1M | $255.9M |
| 4 | Saint Joseph Regional Medical Center INC | Health Care | $138.1M | $823.1M |
| 5 | Saint Joseph Regional Medical Center-plymouth Campus INC | Health Care | $56.5M | $313.7M |
| 6 | The Foundation for the Center for Hospice and Palliative Care INC | Philanthropy, Voluntarism & Grantmaking | $53.6M | $60.5M |
| 7 | Bethel University INC | Education | $44.0M | $47.8M |
| 8 | Garatoni-smith Family Foundation | Philanthropy, Voluntarism & Grantmaking | $21.2M | $51.9M |
| 9 | The Center for Hospice and Palliative Care INC | Human Services | $16.9M | $56.8M |
| 10 | Franciscan Health Foundation INC | Philanthropy, Voluntarism & Grantmaking | $11.3M | $81.0M |
| 11 | St. Joseph the Protector Foundation INC | Human Services | $8.9M | $49.2M |
| 12 | Leep Foundation | Philanthropy, Voluntarism & Grantmaking | $7.4M | $22.0M |
| 13 | Habitat for Humanity International INC | Housing & Shelter | $6.0M | $15.8M |
| 14 | Jaxson William Augustus Swank Foundation | Philanthropy, Voluntarism & Grantmaking | $5.4M | $5.6M |
| 15 | Sterling Group Employee Benefit Tr | Mutual & Membership Benefit | $3.6M | $247K |
| 16 | Indiana Resource Center for Families with Special Needs INC | Education | $3.4M | $559K |
| 17 | Vera Z Dwyer Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $3.4M | $6.3M |
| 18 | Covenant Christian School | Unclassified | $2.9M | $4.5M |
| 19 | Tlcu Financial | Unclassified | $2.9M | $53.1M |
| 20 | Community Development Corporation of Mishawaka Indiana | Community Improvement & Capacity Building | $2.6M | $2.0M |
| 21 | Wyn and Carol Laidig Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.6M | $22.0M |
| 22 | Humane Society of St. Joseph County Indiana INC | Unclassified | $2.6M | $3.9M |
| 23 | Foundation of Saint Joseph Regional Medical Center INC | Health Care | $2.6M | $23.3M |
| 24 | Montessori Academy at Edison Lakes INC | Unclassified | $2.2M | $2.3M |
| 25 | Daniel Laidig Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.9M | $2.9M |
| 26 | Northern Indiana Maternal and Child Health Network INC | Health Care | $1.6M | $883K |
| 27 | Christ Child Society of South Bend INC | Human Services | $1.3M | $2.4M |
| 28 | Heroes Camp INC | Youth Development | $993K | $1.7M |
| 29 | Regional Innovation and Startup Education INC | Education | $891K | $136K |
| 30 | Mittler Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $887K | $3.7M |
| 31 | Hannahs House INC | Human Services | $830K | $1.1M |
| 32 | Schurz Communications Foundation | Unclassified | $770K | $2.7M |
| 33 | Resale to the Rescue INC | Animal-Related | $768K | $121K |
| 34 | Global Partners in Care INC | International, Foreign Affairs & National Security | $721K | $624K |
| 35 | J&s Laidig Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $714K | $7.0M |
| 36 | International Soccer Academy of America Company | Education | $614K | $327K |
| 37 | Pond Foundation INC | Unclassified | $587K | $1.2M |
| 38 | Mishawaka Parks and Recreation Foundation INC | Recreation & Sports | $581K | $598K |
| 39 | Ahepa Dop 60 INC | Housing & Shelter | $579K | $4.0M |
| 40 | Mishawaka Food Pantry INC | Food, Agriculture & Nutrition | $577K | $97K |
| 41 | St. Joseph Valley Assn of Plumbing Heating Cooling Contractors INC | Unclassified | $572K | $1.2M |
| 42 | Housing Assistance Office INC | Housing & Shelter | $538K | $2.4M |
| 43 | School City of Mishawaka Education Foundation INC | Education | $472K | $939K |
| 44 | Hello Gorgeous of Hope INC | Human Services | $380K | $232K |
| 45 | Home Builders Association of St. Joseph Valley INC | Community Improvement & Capacity Building | $380K | $183K |
| 46 | Penn-harris-madison Educational Foundation INC | Philanthropy, Voluntarism & Grantmaking | $345K | $1.3M |
| 47 | St. Alexis Hospital | Unclassified | $314K | $3.5M |
| 48 | Fraternal Order of Police | Unclassified | $314K | $178K |
| 49 | M B T INC | Unclassified | $312K | $656K |
| 50 | Rvwa | Community Improvement & Capacity Building | $308K | $294K |
| 51 | Veterans of Foreign Wars Dept of Indiana Ladies Auxiliary | Unclassified | $279K | $310K |
| 52 | Ambaricho International Prayer and Missions Movement USA INC | Religion-Related | $267K | $292K |
| 53 | Garatoni-smith Scholars Corporation | Education | $247K | $335 |
| 54 | Penn High School Band Boosters | Unclassified | $244K | $46K |
| 55 | Edmondo Deamicis Mutual Aid Society INC | Recreation & Sports | $230K | $281K |
| 56 | Mishawaka Alliance of Care INC | Health Care | $220K | $48K |
| 57 | Broederenkring Club | Mutual & Membership Benefit | $210K | $188K |
| 58 | Meow Mission Limited | Animal-Related | $205K | $173K |
| 59 | Indiana State High School Hockey Association INC | Recreation & Sports | $200K | $191K |
| 60 | Maria Ss Diloreto Italian Mutual Benefit Society INC | Unclassified | $194K | $234K |
| 61 | Fraternal Order of Eagles | Unclassified | $188K | $281K |
| 62 | Bear Reading Center INC | Education | $176K | $368K |
| 63 | United Steelworkers | Unclassified | $173K | $347K |
| 64 | Mishawaka Business Association INC | Unclassified | $168K | $49K |
| 65 | Gymnastics Michiana Booster Club INC | Recreation & Sports | $148K | $37K |
| 66 | McAlpin Family Foundation INC | Education | $145K | $124K |
| 67 | International Association of Fire Fighters | Unclassified | $144K | $193K |
| 68 | Laidig Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $135K | $1.1M |
| 69 | Bittersweet Elementary PTO INC | Education | $134K | $101K |
| 70 | Mishawaka Troop Town | Housing & Shelter | $126K | $592K |
| 71 | Preservation of the Res INC | Environment | $113K | $356K |
| 72 | Maplewood Cemetery Perpetual Care Fund | Mutual & Membership Benefit | $103K | $2.0M |
| 73 | Aging Connections of Michiana | Public & Societal Benefit | $87K | $117K |
| 74 | Elm Road Elementary PTO INC | Unclassified | $87K | $29K |
| 75 | Benjamin Kampondeni & Maureen Mankhwala Charitable Organization | Human Services | $85K | $127K |
| 76 | Summit University INC | Education | $85K | $6K |
| 77 | Acting Ensemble INC | Unclassified | $84K | $251K |
| 78 | Anita@pearson Trust | Human Services | $77K | $587K |
| 79 | Notre Dame Club of St. Joseph Valley Scholarship Trust | Education | $76K | $510K |
| 80 | Club 15 Athletic Association INC | Unclassified | $72K | $256K |
| 81 | Fencing Advisory Associates INC | Unclassified | $72K | $106K |
| 82 | All 4 Animals Rescue Incorporated | Animal-Related | $61K | $11K |
| 83 | Power for Living Ministry INC | Religion-Related | $59K | $6K |
| 84 | Pilgrim Institute | Education | $59K | $48K |
| 85 | International Association of Lions Clubs | Unclassified | $43K | $12K |
| 86 | Workforce Solutions INC | Community Improvement & Capacity Building | $30K | $724 |
| 87 | Wbl Hub Corp. | Education | $29K | $15K |
| 88 | Mishawaka Football Touchdown Club INC | Recreation & Sports | $17K | $5K |
| 89 | Edward N Kalamaros Family Char Fdn INC | Philanthropy, Voluntarism & Grantmaking | $15K | $76K |
| 90 | Mishawaka Historical Museum Corp. | Arts, Culture & Humanities | $10K | $277K |
| 91 | On Eagles Wings INC | Human Services | $7K | $1 |
| 92 | Green Acres Ranch INC | Animal-Related | $6K | $14K |
| 93 | Flamingo Futsal Club | Recreation & Sports | $2K | $2K |
| 94 | Safe Society Foundation INC | Public Safety, Disaster Preparedness & Relief | $700 | $184 |
| 95 | Eckco for Christ INC | Philanthropy, Voluntarism & Grantmaking | $1 | $516 |
| 96 | United States Bowling Congress INC | Recreation & Sports | $0 | $0 |
| 97 | The Church of Pentecost USA INC | Unclassified | $0 | $0 |
| 98 | Grissom Middle School Parent & Teacher Organization | Education | $0 | $0 |
| 99 | Mishawaka Area National Day of Prayer INC | Religion-Related | $0 | $0 |
| 100 | Church Lady and Friends Outreach Ministries INC | Religion-Related | $0 | $0 |