| 1 | Big Ten Conference INC | Unclassified | $934.1M | $292.3M |
| 2 | Dairy Management INC | Unclassified | $165.7M | $25.4M |
| 3 | American Academy of Orthopedic Surgeons | Diseases, Disorders & Medical Disciplines | $96.4M | $192.5M |
| 4 | American Academy of Dermatology INC | Diseases, Disorders & Medical Disciplines | $82.1M | $128.5M |
| 5 | National Milk Producers Federation | Unclassified | $58.1M | $37.5M |
| 6 | American Association of Oral and Maxillofacial Surgeons | Unclassified | $50.7M | $45.3M |
| 7 | American Academy of Dermatology Association INC | Diseases, Disorders & Medical Disciplines | $50.6M | $27.7M |
| 8 | International Sanitary Supply Association | Unclassified | $48.7M | $71.6M |
| 9 | National Housewares Manufacturers Association | Unclassified | $37.6M | $36.3M |
| 10 | United Dairy Industry Association INC | Unclassified | $35.5M | $2.1M |
| 11 | American Association of Orthopaedic Surgeons of America | Community Improvement & Capacity Building | $27.8M | $21.4M |
| 12 | American Association of Nurse Anesthetists | Unclassified | $23.3M | $82.1M |
| 13 | American Academy of Physical Medicine and Rehabilitation | Unclassified | $22.6M | $32.3M |
| 14 | Oral and Maxillofacial Surgery Foundation | Medical Research | $20.5M | $20.4M |
| 15 | American Medical Technologists | Unclassified | $17.9M | $17.1M |
| 16 | Society for Vascular Surgery | Unclassified | $17.7M | $27.0M |
| 17 | Orthopaedic Research and Education Foundation | Medical Research | $13.5M | $21.5M |
| 18 | American Orthopaedic Society for Sports Medicine | Diseases, Disorders & Medical Disciplines | $12.7M | $19.5M |
| 19 | Genyouth INC | Philanthropy, Voluntarism & Grantmaking | $10.8M | $12.0M |
| 20 | Arthroscopy Association of North America INC | Unclassified | $10.4M | $12.6M |
| 21 | American Association of Hip & Knee Surgeons | Unclassified | $10.3M | $12.9M |
| 22 | American Association of Nurse Anesthetists Foundation | Health Care | $10.3M | $15.2M |
| 23 | Burke Group Welfare Plan Trust | Unclassified | $8.2M | $4.1M |
| 24 | American Orthopaedic Association | Diseases, Disorders & Medical Disciplines | $7.1M | $18.6M |
| 25 | Global Dairy Platform INC | Community Improvement & Capacity Building | $6.0M | $1.4M |
| 26 | Food Service Equipment Distributors Association | Unclassified | $5.1M | $3.6M |
| 27 | Dairy Science Institute INC | Food, Agriculture & Nutrition | $4.6M | $17.0M |
| 28 | Arthroscopy Association of North America Education Foundation | Diseases, Disorders & Medical Disciplines | $4.5M | $18.6M |
| 29 | Orthopaedic Research Society | Medical Research | $4.4M | $9.9M |
| 30 | Motion Picture Lab Tech & Film Editors Local 780 Welfare Fund | Unclassified | $4.2M | $15.3M |
| 31 | New England Dairy Promotion Board INC | Unclassified | $4.1M | $826K |
| 32 | Chicago Cosmetologist Association | Unclassified | $4.1M | $2.7M |
| 33 | American College of Prosthodontists | Community Improvement & Capacity Building | $4.1M | $7.0M |
| 34 | William R Rich Foundation | Unclassified | $4.0M | $9.2M |
| 35 | Issa Charities | Philanthropy, Voluntarism & Grantmaking | $3.8M | $6.4M |
| 36 | The Orthopaedic Learning Center | Education | $3.5M | $13.3M |
| 37 | American Concrete Pavement Association | Unclassified | $3.4M | $1.8M |
| 38 | Council on Accreditation of Nurse Anesthetists | Education | $3.0M | $5.5M |
| 39 | American Society of Plumbing Engineers | Unclassified | $2.7M | $4.5M |
| 40 | The Cavaliers Ap&e INC | Arts, Culture & Humanities | $2.6M | $833K |
| 41 | Housewares Charity Foundation | Philanthropy, Voluntarism & Grantmaking | $2.4M | $312K |
| 42 | Society for Vascular Surgery Foundation | Diseases, Disorders & Medical Disciplines | $2.3M | $8.1M |
| 43 | New England Dairy and Food Council | Unclassified | $2.2M | $723K |
| 44 | American College of Prosthodontists Education Foundation | Diseases, Disorders & Medical Disciplines | $2.0M | $9.2M |
| 45 | National Accrediting Agency for Clinical Laboratory Science | Unclassified | $1.9M | $3.5M |
| 46 | Honor Flight Chicago Corp. | Human Services | $1.9M | $2.9M |
| 47 | Midwest Furry Fandom | Animal-Related | $1.9M | $1.2M |
| 48 | Open Doors Organization | Human Services | $1.7M | $1.4M |
| 49 | Dairy Center for Strategic Innovation and Collaboration INC | Community Improvement & Capacity Building | $1.6M | $873K |
| 50 | Foundation for Physical Medicine and Rehabilitation | Medical Research | $1.5M | $3.1M |
| 51 | Unite Here | Unclassified | $1.2M | $1.3M |
| 52 | Alliance for Responsible Consumer Legal Funding | Community Improvement & Capacity Building | $714K | $199K |
| 53 | Center for Orthopaedic Trauma Advancement | Philanthropy, Voluntarism & Grantmaking | $587K | $679K |
| 54 | Foundation for Arthroplasty Research and Education | Medical Research | $529K | $1.8M |
| 55 | Illinois Public Employer Labor Relations Association | Unclassified | $344K | $189K |
| 56 | Innovative Pavement Research Foundation | Science & Technology | $282K | $446K |
| 57 | Rosemont Illinois Chamber of Commerce | Community Improvement & Capacity Building | $238K | $216K |
| 58 | Bill and Orli Staley Foundation | Unclassified | $215K | $311K |
| 59 | Association of Program Directors in Vascular Surgery | Medical Research | $210K | $385K |
| 60 | Society for Vascular Nursing INC | Unclassified | $178K | $133K |
| 61 | Feda Education Foundation | Philanthropy, Voluntarism & Grantmaking | $154K | $38K |
| 62 | Biologic Association | Medical Research | $96K | $362K |
| 63 | Rosemont Public Safety Charitable Foundation | Public Safety, Disaster Preparedness & Relief | $94K | $77K |
| 64 | McShane Foundation | Unclassified | $90K | $1.3M |
| 65 | Delaware Valley Vascular Society INC | Unclassified | $86K | $110K |
| 66 | National Basketball Association Physicians Society Foundation | Diseases, Disorders & Medical Disciplines | $85K | $358K |
| 67 | Julia Vacala Foundation | Medical Research | $78K | $146K |
| 68 | Culligan Cares Foundation | Philanthropy, Voluntarism & Grantmaking | $37K | $187K |
| 69 | Western Society of Engineers | Education | $36K | $165K |
| 70 | Healthcare Surfaces Summit | Education | $34K | $5K |
| 71 | Fralens Foundation | Unclassified | $3K | $1K |
| 72 | American Society of Plumbing Engineers Research Foundation INC | Unclassified | $1K | $56K |
| 73 | Society of Surgical Oncology INC | Unclassified | $0 | $0 |
| 74 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 75 | National Treasury Employees Union | Unclassified | $0 | $0 |
| 76 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 77 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 78 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 79 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 80 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 81 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 82 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 83 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 84 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 85 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 86 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 87 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 88 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 89 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 90 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 91 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 92 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 93 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 94 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 95 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 96 | American College of Prosthodontists | Community Improvement & Capacity Building | $0 | $0 |
| 97 | National Dairy Council | Food, Agriculture & Nutrition | $0 | $0 |
| 98 | Our Lady of Hope Church | Unclassified | $0 | $0 |
| 99 | National Dairy Leaders Conference | Unclassified | $0 | $0 |
| 100 | Illinois Association of Environmental Professionals | Environment | $0 | $0 |