| 1 | Midwest Medical Center | Health Care | $44.4M | $64.4M |
| 2 | Riverview Center INC | Education | $3.2M | $2.3M |
| 3 | The Workshop | Employment | $2.8M | $9.1M |
| 4 | Greater Galena Marketing INC | Community Improvement & Capacity Building | $2.4M | $1.7M |
| 5 | Galena Art & Recreation Center | Unclassified | $1.2M | $1.9M |
| 6 | Galena Golf Club | Community Improvement & Capacity Building | $1.2M | $482K |
| 7 | Galena Area Emergency Medical Service District | Health Care | $1.1M | $2.4M |
| 8 | Galena-jo Daviess County Historical Society | Unclassified | $873K | $5.2M |
| 9 | Chicago Athenaeum the Center for Architecture Art and Urban Studies | Mental Health & Crisis Intervention | $611K | $865K |
| 10 | National Rural Letter Carriers Association | Unclassified | $548K | $759K |
| 11 | Galena Foundation INC | Unclassified | $448K | $1.5M |
| 12 | Galena Center for the Arts INC | Arts, Culture & Humanities | $446K | $2.3M |
| 13 | Galena Education Foundation | Unclassified | $431K | $1.0M |
| 14 | Benevolent & Protective Order of Elks of the USA | Unclassified | $345K | $557K |
| 15 | Galena Volunteer Fire Department | Health Care | $296K | $480K |
| 16 | Fraternal Order of Eagles | Unclassified | $240K | $142K |
| 17 | Greenwood Cemetery of the City of Galena | Unclassified | $140K | $1.4M |
| 18 | International Association of Lions Clubs | Unclassified | $127K | $47K |
| 19 | United Churches of Galena INC | Human Services | $122K | $217K |
| 20 | Jo Daviess Residential Services INC | Unclassified | $91K | $675K |
| 21 | Midwest Medical Foundation | Health Care | $77K | $29K |
| 22 | Jo Daviess County Beef Association | Education | $74K | $52K |
| 23 | Sizzle Foundation | Community Improvement & Capacity Building | $73K | $119K |
| 24 | Jo Daviess County Country Fair Charities INC | Philanthropy, Voluntarism & Grantmaking | $63K | $99K |
| 25 | Galena Territory Foundation | Education | $59K | $137K |
| 26 | Galena Area Chamber of Commerce | Unclassified | $53K | $46K |
| 27 | Galena Downtown Business Corp Nfp | Community Improvement & Capacity Building | $40K | $37K |
| 28 | Galena S Living History Alliance Nfp | Environment | $14K | $7K |
| 29 | American Natural Heritage Foundation and Mueller Fam Chartit | Environment | $1 | $1 |
| 30 | Consider Source | Mental Health & Crisis Intervention | $0 | $0 |
| 31 | US Grant Center INC | Arts, Culture & Humanities | $0 | $0 |
| 32 | Knights of Columbus | Unclassified | $0 | $0 |
| 33 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 34 | National Rural Letter Carriers Association | Unclassified | $0 | $0 |
| 35 | National Rural Letter Carriers Association | Unclassified | $0 | $0 |
| 36 | Bible Alive | Religion-Related | $0 | $0 |
| 37 | Lord of Love Lutheran Church | Unclassified | $0 | $0 |
| 38 | Friendship Quilters | Unclassified | $0 | $0 |
| 39 | Galena Cultural Arts Alliance | Arts, Culture & Humanities | $0 | $0 |
| 40 | 4041 Foundation | Crime & Legal-Related | $0 | $0 |
| 41 | Galena Comm Development Fund INC | Community Improvement & Capacity Building | $0 | $0 |
| 42 | Jo Daviess-stronghurst Mutual Insurance Co | Unclassified | $0 | $0 |
| 43 | St. Michael Church | Unclassified | $0 | $0 |
| 44 | St. Mary Church | Unclassified | $0 | $0 |
| 45 | Veterans of Foreign Wars Department of Illinois | Unclassified | $0 | $0 |
| 46 | St. Matthew Lutheran Church | Religion-Related | $0 | $0 |
| 47 | Galena United Methodist Church | Unclassified | $0 | $0 |
| 48 | League of Women Voters of Illinois | Unclassified | $0 | $0 |
| 49 | Galena Boat Club INC | Unclassified | $0 | $0 |
| 50 | Galena Bible Church | Unclassified | $0 | $0 |
| 51 | Planetary Studies Foundation Ltd | Unclassified | $0 | $0 |
| 52 | New Covenant Assembly of God | Unclassified | $0 | $0 |
| 53 | Kiwanis International INC | Unclassified | $0 | $0 |
| 54 | Hundred Club of Jo Daviess County | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 55 | Friends of Galena Public Library INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 56 | Department of Illinois VFW Auxiliary INC | Public & Societal Benefit | $0 | $0 |
| 57 | American Legion | Public & Societal Benefit | $0 | $0 |
| 58 | Purrfection Animal Rescue Galena Nfp | Animal-Related | $0 | $0 |
| 59 | His Helping Hands Rescue | Animal-Related | $0 | $0 |
| 60 | The Hope Foundation of Jo Daviess County | Human Services | $0 | $0 |
| 61 | All River Road Talent | Arts, Culture & Humanities | $0 | $0 |
| 62 | Galena Ghostbusters | Public & Societal Benefit | $0 | $0 |
| 63 | Galena Kiwanis Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 64 | Future Farmers of America State Associations & Local Chapter | Unclassified | $0 | $0 |
| 65 | Belvedere Mansion and Gardens Foundation INC Nfp | Arts, Culture & Humanities | $0 | $0 |
| 66 | Audible Visions | Diseases, Disorders & Medical Disciplines | $0 | $0 |
| 67 | Parent Booster USA INC | Unclassified | $0 | $0 |
| 68 | Galena Shakespeare Festival | Arts, Culture & Humanities | $0 | $0 |