| 1 | St. Louis Prospects Hockey Club | Recreation & Sports | $1.9M | $46K |
| 2 | Sophia and Elmer Oerter Charitable Foundation | Unclassified | $1.7M | $3.9M |
| 3 | Humane Society of Monroe County Illinois | Animal-Related | $1.0M | $3.5M |
| 4 | Songs4soldiers Nfp | Arts, Culture & Humanities | $734K | $525K |
| 5 | American Legion Post 581 | Unclassified | $715K | $744K |
| 6 | B K Bryant Foundation | Unclassified | $654K | $697K |
| 7 | Monroe County Christian School | Education | $536K | $970K |
| 8 | Columbia Crew Soccer Club | Recreation & Sports | $520K | $364K |
| 9 | Columbia Gymnastic Association | Unclassified | $484K | $883K |
| 10 | Dorothy Weinel Eppinger Foundation | Unclassified | $435K | $1.1M |
| 11 | Aerocareers Nfp | Education | $154K | $176K |
| 12 | Knights of the Cauliflower Ear Ltd | Recreation & Sports | $153K | $4K |
| 13 | Fury Fastpitch Stl | Recreation & Sports | $141K | $40K |
| 14 | Columbia Bath & Tennis Club | Unclassified | $137K | $238K |
| 15 | Blue Jay Football Association | Recreation & Sports | $129K | $145K |
| 16 | Monroe County Tribe Association INC | Recreation & Sports | $125K | $60K |
| 17 | Marians Place Wellness & Nature Sanctuary | Human Services | $118K | $86K |
| 18 | Crowder Fam Foundation | Philanthropy, Voluntarism & Grantmaking | $114K | $481K |
| 19 | Columbia Baseball Club INC | Recreation & Sports | $91K | $10K |
| 20 | Seeds of Fire | Religion-Related | $88K | $4K |
| 21 | Columbia Athletic Association INC | Recreation & Sports | $86K | $84K |
| 22 | Columbia Aero Club INC | Recreation & Sports | $80K | $34K |
| 23 | Columbia Music Booster INC | Education | $70K | $139K |
| 24 | Knights of Columbus | Unclassified | $68K | $41K |
| 25 | Future Farmers of America and Its State Associations & Local Chapter | Unclassified | $66K | $116K |
| 26 | Actors Attic | Arts, Culture & Humanities | $57K | $11K |
| 27 | Stacey Cooper Foundation | Human Services | $50K | $39K |
| 28 | Columbia Kiwanis Foundation INC | Education | $38K | $27K |
| 29 | Columbia Amateur Athletics Foundation | Recreation & Sports | $22K | $10K |
| 30 | Alf Interface Academy INC | Health Care | $22K | $25K |
| 31 | Borrowed Time 151 Charitable Foundation | Diseases, Disorders & Medical Disciplines | $21K | $21K |
| 32 | Columbia Eagles Athletic Boosterclub | Education | $18K | $22K |
| 33 | The United States Pony Clubs INC | Unclassified | $0 | $0 |
| 34 | National Rural Letter Carriers Association | Unclassified | $0 | $0 |
| 35 | Peterstown Heritage Society INC | Arts, Culture & Humanities | $0 | $0 |
| 36 | Brotherhood of Locomotive Engineers and Trainmen | Unclassified | $0 | $0 |
| 37 | National Association of Retired & Veteran Railway Employees INC | Unclassified | $0 | $0 |
| 38 | Society of St. Vincent de Paul | Human Services | $0 | $0 |
| 39 | Healing Sisters | Crime & Legal-Related | $0 | $0 |
| 40 | Columbia Chamber of Commerce | Community Improvement & Capacity Building | $0 | $0 |
| 41 | Life Community Church | Unclassified | $0 | $0 |
| 42 | Play for Purpose Veterans Foundation | Human Services | $0 | $0 |
| 43 | Strike & Spare Club | Recreation & Sports | $0 | $0 |
| 44 | Columbia Illinois Historical Society | Arts, Culture & Humanities | $0 | $0 |
| 45 | Heart of God Ministries | Religion-Related | $0 | $0 |
| 46 | Moms on a Mission | Human Services | $0 | $0 |
| 47 | Optimist International | Unclassified | $0 | $0 |
| 48 | St. Pauls Lutheran Church | Unclassified | $0 | $0 |
| 49 | Deer Hill Church Rr 2 | Unclassified | $0 | $0 |
| 50 | First Baptist Church of Columbia | Unclassified | $0 | $0 |
| 51 | Maple Leaf Gun Club INC | Recreation & Sports | $0 | $0 |
| 52 | Bethany Church Columbia Illinois Nfp | Religion-Related | $0 | $0 |
| 53 | Momentum Church INC | Religion-Related | $0 | $0 |
| 54 | Waterloo Columbia Church of Christ | Unclassified | $0 | $0 |
| 55 | Evangel Assembly of God | Unclassified | $0 | $0 |
| 56 | Illinois Congress of Parents Teachers | Education | $0 | $0 |
| 57 | Sister Cities of Columbia Illinois INC | Community Improvement & Capacity Building | $0 | $0 |
| 58 | Evangelical Lutheran Church in America | Unclassified | $0 | $0 |
| 59 | The United States Air Force Academy Parents Club of Metropolitan St. | Public & Societal Benefit | $0 | $0 |
| 60 | Hope Christian Church | Religion-Related | $0 | $0 |
| 61 | Columbia School District Foundation INC | Education | $0 | $0 |
| 62 | Maple Grove Civic Association | Youth Development | $0 | $0 |
| 63 | Columbia | Unclassified | $0 | $0 |
| 64 | Columbia Sportsmens Club | Recreation & Sports | $0 | $0 |
| 65 | Rotary International | Unclassified | $0 | $0 |
| 66 | International Association of Lions Clubs | Unclassified | $0 | $0 |
| 67 | Friends of the Library of Columbia Illinois | Unclassified | $0 | $0 |
| 68 | Columbia Historic Main Street | Community Improvement & Capacity Building | $0 | $0 |
| 69 | Fund My Team Nfp | Arts, Culture & Humanities | $0 | $0 |
| 70 | La Leche League of the United States of America | Unclassified | $0 | $0 |
| 71 | Sand Bank School Historical Society | Arts, Culture & Humanities | $0 | $0 |
| 72 | Rotary International | Unclassified | $0 | $0 |
| 73 | Columbias Resourceful Organization of Women Networking | Community Improvement & Capacity Building | $0 | $0 |
| 74 | Play Columbia Parks and Recreation Foundation | Community Improvement & Capacity Building | $0 | $0 |
| 75 | Grace Adoption INC | Religion-Related | $0 | $0 |
| 76 | American Board of Craniofacial Dental Sleep Medicine | Community Improvement & Capacity Building | $0 | $0 |
| 77 | New Palestine Cemetery Association | Unclassified | $0 | $0 |
| 78 | Columbia Volunteer Fire Department | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 79 | Friends of the Columbia Il Depot | Arts, Culture & Humanities | $0 | $0 |
| 80 | Columbia Caring for Our Community | Human Services | $0 | $0 |
| 81 | Columbia Rotary Charities INC | Community Improvement & Capacity Building | $0 | $0 |
| 82 | So Will I Orphan Care Nfp | Human Services | $0 | $0 |
| 83 | Hope Food Pantry Nfp | Food, Agriculture & Nutrition | $0 | $0 |
| 84 | John 1 5 | Religion-Related | $0 | $0 |
| 85 | Nofa Jeep Army | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 86 | Eves Restoration Ministries | Housing & Shelter | $0 | $0 |