| 1 | Fairview Heights Medical Group Sc | Health Care | $167.7M | $33.8M |
| 2 | Challenge Unlimited INC | Employment | $33.8M | $20.8M |
| 3 | Bon Eau Foundation | Philanthropy, Voluntarism & Grantmaking | $32.1M | $140K |
| 4 | Senior Services Plus INC | Unclassified | $17.6M | $14.1M |
| 5 | Residential Options INC | Housing & Shelter | $15.0M | $17.5M |
| 6 | Riverbend Head Start Delegate INC | Education | $12.8M | $3.3M |
| 7 | Great Rivers & Routes Tourism Bureau | Community Improvement & Capacity Building | $7.1M | $4.5M |
| 8 | Eagle Forum Education and Legal Defense Fund | Civil Rights, Social Action & Advocacy | $5.7M | $18.4M |
| 9 | Alton Memorial Health Services Foundation | Unclassified | $5.3M | $45.0M |
| 10 | Bound to Stay Bound Books Foundation | Unclassified | $3.6M | $4.2M |
| 11 | Jennie D Hayner Library Association | Education | $2.9M | $3.5M |
| 12 | Advanced Outsource Solutions INC | Employment | $2.7M | $718K |
| 13 | Oasis Womens Center | Human Services | $1.8M | $2.6M |
| 14 | Alton Womans Home Association | Unclassified | $1.6M | $4.1M |
| 15 | Riverbend Head Start & Family Services INC | Health Care | $1.4M | $2.6M |
| 16 | Janet Simpson Tr Fbo Humane Society of Mo Ua 08091987 | Animal-Related | $1.3M | $3.9M |
| 17 | International Brotherhood of Electrical Workers | Unclassified | $1.2M | $1.1M |
| 18 | International Brotherhood of Teamsters | Unclassified | $1.1M | $596K |
| 19 | Lantern Network | Religion-Related | $1.1M | $1.1M |
| 20 | Impact Cil | Unclassified | $1.1M | $746K |
| 21 | Alton City Cemetery | Mutual & Membership Benefit | $881K | $1.9M |
| 22 | YWCA Southwestern Illinois | Human Services | $764K | $1.0M |
| 23 | The Restore Network | Human Services | $761K | $56K |
| 24 | Congress of Independent Unions | Unclassified | $633K | $375K |
| 25 | Maurice C Funk Second Amendment Trust Agreement | Philanthropy, Voluntarism & Grantmaking | $627K | $1.8M |
| 26 | Boys & Girls Club of Alton INC | Youth Development | $609K | $684K |
| 27 | Great Rivers Land Preservation Association INC | Environment | $556K | $15.1M |
| 28 | State Employees Credit Union | Unclassified | $554K | $6.5M |
| 29 | Madison County Urban League INC | Human Services | $526K | $102K |
| 30 | Marquette Catholic High Schoolfoundation | Philanthropy, Voluntarism & Grantmaking | $496K | $693K |
| 31 | Carlinville Area Hospital Foundation | Health Care | $470K | $1.8M |
| 32 | Veterans of Foreign Wars Department of Illinois | Unclassified | $469K | $151K |
| 33 | Piasa Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $434K | $2.7M |
| 34 | Alton Little Theater INC | Arts, Culture & Humanities | $378K | $256K |
| 35 | Crisis Food Center INC | Human Services | $361K | $818K |
| 36 | Amys Crossing | Housing & Shelter | $296K | $1.4M |
| 37 | Sacred Spaces of Care | Human Services | $288K | $26K |
| 38 | Shc Foundation | Philanthropy, Voluntarism & Grantmaking | $284K | $9K |
| 39 | Yakubian Homes | Housing & Shelter | $278K | $1.0M |
| 40 | Triopia Public Schools Foundation | Education | $274K | $397K |
| 41 | Upper Alton Cemetery | Unclassified | $264K | $1.4M |
| 42 | Edna & Emma O Sawyer Charitable Tr 46343600 | Philanthropy, Voluntarism & Grantmaking | $253K | $225K |
| 43 | Eagle Forum | Public & Societal Benefit | $249K | $2.9M |
| 44 | M H C Development Company INC | Housing & Shelter | $231K | $470K |
| 45 | Hempel House | Housing & Shelter | $217K | $662K |
| 46 | Bakery Confectionery Tobacco Workers and Grain Millers Intl Uni | Unclassified | $204K | $441K |
| 47 | Neca-ibew Local 649 Joint Apprenticeship & Training Tr Fund | Employment | $202K | $2.3M |
| 48 | Summers-port INC Godfrey Ill | Unclassified | $201K | $376K |
| 49 | Alton Owls Club | Unclassified | $174K | $223K |
| 50 | Alton Forward | Community Improvement & Capacity Building | $173K | $38K |
| 51 | Eagle Forum Foundation | Education | $168K | $218K |
| 52 | Alton Main Street INC | Unclassified | $155K | $94K |
| 53 | Siu Dental Associates | Education | $146K | $179K |
| 54 | Imerge INC Nfp | Youth Development | $138K | $2K |
| 55 | Christmas Wonderland INC | Religion-Related | $107K | $112K |
| 56 | Alton Band & Orchestra Builders | Public Safety, Disaster Preparedness & Relief | $106K | $126K |
| 57 | Mustache March 4 Pd INC | Public Safety, Disaster Preparedness & Relief | $97K | $30K |
| 58 | Jacoby Arts Center | Unclassified | $96K | $188K |
| 59 | Marquette Booster Club INC | Education | $94K | $49K |
| 60 | Alton Symphony Orchestra | Unclassified | $93K | $91K |
| 61 | American Legion | Unclassified | $86K | $1 |
| 62 | Alton Educational Foundation | Education | $83K | $193K |
| 63 | Food is Love Production Company INC | Arts, Culture & Humanities | $73K | $4K |
| 64 | United Steelworkers | Unclassified | $70K | $384K |
| 65 | Bluff City Athletic Club Nfp | Youth Development | $68K | $51K |
| 66 | Migratory Waterfowl Hunters INC | Unclassified | $66K | $78K |
| 67 | International Association of Fire Fighters | Unclassified | $65K | $132K |
| 68 | American Federation of State County & Municipal Employees | Unclassified | $59K | $130K |
| 69 | National Association of Letter Carriers | Unclassified | $59K | $158K |
| 70 | Alton Volunteer Emergency Corps INC | Unclassified | $53K | $79K |
| 71 | Kathleen B Youell Scholarship Fund | Philanthropy, Voluntarism & Grantmaking | $51K | $200K |
| 72 | Beem Family Foundation | Community Improvement & Capacity Building | $51K | $154K |
| 73 | Alton Youth Symphony | Unclassified | $51K | $508K |
| 74 | Knights of Columbus | Unclassified | $48K | $278K |
| 75 | 100 Black Men of Alton INC | Unclassified | $38K | $7K |
| 76 | Borman Brothers Foundation | Philanthropy, Voluntarism & Grantmaking | $31K | $250 |
| 77 | Ancient Free & Accepted Masons of Illinois | Unclassified | $28K | $777K |
| 78 | Improved Benevolent & Protective Order of Elks of the World | Unclassified | $28K | $38K |
| 79 | Hoagland Fam Foundation | Philanthropy, Voluntarism & Grantmaking | $26K | $294K |
| 80 | Junior League of Greater Alton INC | Community Improvement & Capacity Building | $11K | $57K |
| 81 | Salt - Student Athletes Leading Tomorrow | Recreation & Sports | $10K | $273 |
| 82 | Great Rivers Tourism Foundation | Recreation & Sports | $9K | $41K |
| 83 | Alton Museum of History & Art INC Amha | Arts, Culture & Humanities | $8K | $73K |
| 84 | Totally Christ Ministries INC | Religion-Related | $3K | $1 |
| 85 | Franklin Lodge No 25 Scholarship Fund INC | Unclassified | $2K | $63K |
| 86 | Riverbender Com Community Center | Human Services | $114 | $23K |
| 87 | Zion Evangelical Presbyterian Church of Fosterburg Illinois | Unclassified | $0 | $0 |
| 88 | East End Foundation | Education | $0 | $0 |
| 89 | Faith Fellowship | Religion-Related | $0 | $0 |
| 90 | Whole Truth Church of Christ | Religion-Related | $0 | $0 |
| 91 | Trinity Lutheran Church Cemetery Association | Mutual & Membership Benefit | $0 | $0 |
| 92 | Holy Faith Church of God in Christinc | Religion-Related | $0 | $0 |
| 93 | Nazarene Acres INC | Unclassified | $0 | $0 |
| 94 | Heartland Baptist Church | Unclassified | $0 | $0 |
| 95 | Alton Area Landmarks Association INC | Unclassified | $0 | $0 |
| 96 | Open Door Ministries INC | Unclassified | $0 | $0 |
| 97 | Disabled American Veterans Auxiliary INC | Unclassified | $0 | $0 |
| 98 | Omicron Kappa Upsilon-honorary Dental Society | Unclassified | $0 | $0 |
| 99 | Tanya Brown Ministries | Religion-Related | $0 | $0 |
| 100 | United Fellowship International Ministries INC | Religion-Related | $0 | $0 |