| 1 | Southeastern Guide Dogs INC | Human Services | $44.6M | $106.5M |
| 2 | Early Learning Coalition of Manatee County INC | Education | $36.2M | $7.9M |
| 3 | Renaissance Arts and Education INC | Education | $33.3M | $50.7M |
| 4 | Bradenton Yacht Club INC | Unclassified | $5.3M | $5.3M |
| 5 | Palmetto Charter School INC | Education | $5.3M | $12.0M |
| 6 | Southeastern Guide Dogs INC Endowment Trust | Diseases, Disorders & Medical Disciplines | $4.9M | $7.8M |
| 7 | Manatee River Fair Association INC | Recreation & Sports | $1.9M | $5.6M |
| 8 | Palmetto Lodge No 2117 Loyal Order of Moose | Unclassified | $1.4M | $834K |
| 9 | Take Stock in Children of Manatee County INC | Philanthropy, Voluntarism & Grantmaking | $1.4M | $5.1M |
| 10 | Healthy Start Coalition of Manatee County INC | Unclassified | $1.4M | $468K |
| 11 | Genesis Health Services INC | Health Care | $1.2M | $848K |
| 12 | Guardian Angels of Sw Florida INC | Human Services | $845K | $3.9M |
| 13 | Feeding Empty Little Tummies INC | Food, Agriculture & Nutrition | $771K | $925K |
| 14 | Palmetto Youth Center | Unclassified | $741K | $693K |
| 15 | Am and Fm Enterprise INC | Human Services | $535K | $54K |
| 16 | Gulf Shellfish Institute INC | Food, Agriculture & Nutrition | $505K | $69K |
| 17 | Florida Federation of Fairs and Livestock Shows | Unclassified | $424K | $354K |
| 18 | North River Care INC | Human Services | $392K | $517K |
| 19 | American Legion | Unclassified | $354K | $624K |
| 20 | From Cradle to College Foundation | Philanthropy, Voluntarism & Grantmaking | $328K | $195K |
| 21 | North Carolina Health Information Management Association | Health Care | $321K | $353K |
| 22 | Florida Citrus Processors Association | Unclassified | $320K | $582K |
| 23 | Educational Consultants Consortium INC | Education | $286K | $546K |
| 24 | Benevolent & Protective Order of Elks of the USA | Mutual & Membership Benefit | $286K | $388K |
| 25 | Anchor House INC | Religion-Related | $270K | $356K |
| 26 | St. John Missionary Baptist Church of Palmetto INC | Religion-Related | $254K | $1.5M |
| 27 | Hand Up to Victory INC | Religion-Related | $249K | $67K |
| 28 | Florida Preborn Rescue INC | Education | $246K | $29K |
| 29 | Palmetto Athletic & Academic Association INC | Education | $211K | $67K |
| 30 | North River Prevention Partners INC | Unclassified | $202K | $40K |
| 31 | University of Florida | Youth Development | $190K | $838K |
| 32 | Palmetto Charter PTO INC | Education | $163K | $41K |
| 33 | Manatee River Youth Sailing INC | Unclassified | $156K | $1.2M |
| 34 | Veterans of Foreign Wars of the United States Dept of Florida | Unclassified | $118K | $20K |
| 35 | Tuf All-stars INC | Recreation & Sports | $118K | $7K |
| 36 | North Manatee Storm INC | Recreation & Sports | $116K | $34K |
| 37 | Pro Youth Foundation INC | Youth Development | $110K | $69K |
| 38 | Gulf Coast Juniors Volleyball Club INC | Recreation & Sports | $95K | $24K |
| 39 | All Kitty Korner INC | Animal-Related | $78K | $179K |
| 40 | Rubonia Community Association INC | Human Services | $77K | $23K |
| 41 | Preaching Vehicle for Kingdom Evangelizers INC | Philanthropy, Voluntarism & Grantmaking | $60K | $47K |
| 42 | Gillette Cemetery INC | Unclassified | $58K | $474K |
| 43 | Palmetto High School Athletic Booster Club INC | Education | $55K | $17K |
| 44 | Virgil Mills Elementary Parent Teacher Organization | Education | $53K | $73K |
| 45 | It Works Gives Back Foundation INC | Philanthropy, Voluntarism & Grantmaking | $41K | $35K |
| 46 | Global Help Ministry INC | Religion-Related | $34K | $83K |
| 47 | Clearwater St. Petersburg Ski Andsports Club INC | Recreation & Sports | $32K | $31K |
| 48 | South Carolina Medical Record Association | Unclassified | $30K | $29K |
| 49 | M&m Mission INC | Philanthropy, Voluntarism & Grantmaking | $29K | $1 |
| 50 | Strength in Action INC | Human Services | $22K | $101K |
| 51 | Great Mates | Education | $15K | $7K |
| 52 | Rick and Jo Berquist Foundation | Philanthropy, Voluntarism & Grantmaking | $15K | $32K |
| 53 | The Palmetto Historical Commission INC | Arts, Culture & Humanities | $9K | $163K |
| 54 | Dr Goodburns Foundation INC | Health Care | $6K | $2K |
| 55 | Canine Care USA Corporation | Animal-Related | $2K | $1 |
| 56 | Peter Michael Stellato Charity INC | Human Services | $2K | $2K |
| 57 | Hruby Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1 | $1 |
| 58 | Matthew a Knight Foundation INC | Human Services | $0 | $0 |
| 59 | Intervention Before Crisis | Youth Development | $0 | $0 |
| 60 | Amazing Grace Church of God in Christ INC | Religion-Related | $0 | $0 |
| 61 | Crossroads Christian Church INC | Religion-Related | $0 | $0 |
| 62 | Iglesia Tabernaculo de la Uncion | Religion-Related | $0 | $0 |
| 63 | Manatee County Friends of Extension INC | Food, Agriculture & Nutrition | $0 | $0 |
| 64 | Dream Big - Do It Big INC | Youth Development | $0 | $0 |
| 65 | Macys Miracle Foundation INC | Diseases, Disorders & Medical Disciplines | $0 | $0 |
| 66 | Disabled American Veterans Auxiliary INC | Public & Societal Benefit | $0 | $0 |
| 67 | Church of the Harvest Sbc | Unclassified | $0 | $0 |
| 68 | Open Door Mission INC | Health Care | $0 | $0 |
| 69 | Victorious Life Christian Church INC | Religion-Related | $0 | $0 |
| 70 | Life Changers International Ministries | Religion-Related | $0 | $0 |
| 71 | National Exchange Club | Unclassified | $0 | $0 |
| 72 | Couch Music Education Foundation INC | Education | $0 | $0 |
| 73 | North River Firefighter Organization INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 74 | Equine Emergency Rescue & Relief INC | Human Services | $0 | $0 |
| 75 | American Legion Auxiliary | Unclassified | $0 | $0 |
| 76 | United for Missouris Future | Public & Societal Benefit | $0 | $0 |
| 77 | Btn Films INC | Arts, Culture & Humanities | $0 | $0 |
| 78 | Genuine Hope Ministries INC | Religion-Related | $0 | $0 |
| 79 | Radiant Dance Booster Club INC | Arts, Culture & Humanities | $0 | $0 |
| 80 | Clara Mae Foundation INC | Housing & Shelter | $0 | $0 |
| 81 | Thunderbird Labs INC | Science & Technology | $0 | $0 |
| 82 | Network Empowerment INC | Community Improvement & Capacity Building | $0 | $0 |
| 83 | Embrace Love Ministries | Religion-Related | $0 | $0 |
| 84 | Fl Agents of God | Religion-Related | $0 | $0 |
| 85 | Patriot Models | Public & Societal Benefit | $0 | $0 |
| 86 | Raices Art Therapy | Arts, Culture & Humanities | $0 | $0 |
| 87 | Manatee County Farm City Week INC | Food, Agriculture & Nutrition | $0 | $0 |
| 88 | Phoenix Project INC | Human Services | $0 | $0 |
| 89 | S&t Entertainment Group Incorporated | Youth Development | $0 | $0 |
| 90 | Dmt Charitable Corporation | Education | $0 | $0 |
| 91 | Next Play INC | Youth Development | $0 | $0 |
| 92 | Ruthies House of Hope | Human Services | $0 | $0 |
| 93 | House of Compassion and Hope | International, Foreign Affairs & National Security | $0 | $0 |
| 94 | Nonprofit Events INC | Human Services | $0 | $0 |
| 95 | She Leads Ministries | Religion-Related | $0 | $0 |
| 96 | Kathryn J Meredith Charitable Found Ation INC | Human Services | $0 | $0 |
| 97 | Vetjets USA Corp. | Public & Societal Benefit | $0 | $0 |
| 98 | Lost Pets Foundation INC | Animal-Related | $0 | $0 |
| 99 | Clv Residents Club | Recreation & Sports | $0 | $0 |
| 100 | Lightsitetv INC | Religion-Related | $0 | $0 |