| 1 | Shadow Wood Country Club INC | Recreation & Sports | $27.0M | $73.4M |
| 2 | Wildcat Run Country Club Association INC | Unclassified | $8.4M | $34.8M |
| 3 | Estero Country Club INC | Recreation & Sports | $8.2M | $22.4M |
| 4 | Abantika Piyush Shah Foundation | Philanthropy, Voluntarism & Grantmaking | $7.8M | $21.9M |
| 5 | Stanley Lee Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $4.3M | $13.6M |
| 6 | Idiopathic Pulmonary Fibrosis Foundation | Diseases, Disorders & Medical Disciplines | $2.9M | $2.7M |
| 7 | Life Choice Crisis Pregnancy Center INC | Health Care | $2.7M | $4.5M |
| 8 | Wayne C Kaufmann Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $2.1M | $16.8M |
| 9 | Salamone Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.1M | $3.1M |
| 10 | The Southwest Florida Foundation Incorporated | Philanthropy, Voluntarism & Grantmaking | $1.7M | $1.1M |
| 11 | Gulfshore Opera INC | Arts, Culture & Humanities | $1.1M | $701K |
| 12 | Estero Fire Rescue Retiree Insurance Trust Fund | Mutual & Membership Benefit | $1.1M | $1.6M |
| 13 | David F & Hallie F Schneeweiss Charitable Tr 12301999 | Philanthropy, Voluntarism & Grantmaking | $1.1M | $1.4M |
| 14 | Southwest Florida Incorporated | Unclassified | $1.1M | $534K |
| 15 | W E Cross Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.0M | $7.9M |
| 16 | Wings of Shelter Intl INC | International, Foreign Affairs & National Security | $753K | $530K |
| 17 | Junior Everblades Hockey Association INC | Recreation & Sports | $714K | $385K |
| 18 | Multiple Sclerosis Center of Southwest Florida INC | Health Care | $686K | $1.0M |
| 19 | Orndorff Family Foundation | Philanthropy, Voluntarism & Grantmaking | $549K | $2.7M |
| 20 | Corkscrew Regional Ecosystem Watershed Trust INC | Environment | $499K | $2.0M |
| 21 | West Bay Community Charitable Foundation INC | Human Services | $475K | $89K |
| 22 | Ken and Ann Douglas Charitable Foundation Tr Dated 10-18-00 | Philanthropy, Voluntarism & Grantmaking | $453K | $1.5M |
| 23 | Tarquini Foundation | Unclassified | $446K | $115K |
| 24 | Benevolent and Protective Order of Elks of the USA | Unclassified | $434K | $820K |
| 25 | Copperleaf Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $372K | $685K |
| 26 | Alliance for Period Supplies of Swfl | Health Care | $337K | $317K |
| 27 | Estero Forever Foundation INC | Community Improvement & Capacity Building | $279K | $419K |
| 28 | Misty Mountain Family Enrichment Center | Mental Health & Crisis Intervention | $267K | $328K |
| 29 | Spring Run Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $252K | $54K |
| 30 | Almalinux Os Foundation | Unclassified | $252K | $226K |
| 31 | Southwest Florida Swim Club INC | Recreation & Sports | $248K | $68K |
| 32 | Pelican Sound Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $227K | $36K |
| 33 | Wildcat Run Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $216K | $38K |
| 34 | 11 11 Fund INC | Human Services | $213K | $85K |
| 35 | Southwest Florida Urban Search and Rescue Florida Task Force 6 INC | Public Safety, Disaster Preparedness & Relief | $209K | $468K |
| 36 | Estero Chamber of Commerce | Unclassified | $201K | $82K |
| 37 | The@holewinski Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $199K | $1.0M |
| 38 | Pinewoods Elementary School Parent Teacher Organization INC | Education | $194K | $122K |
| 39 | Bodhi Foundation INC | Human Services | $160K | $679K |
| 40 | India Association of Fort Myers INC | Arts, Culture & Humanities | $153K | $166K |
| 41 | Estero San Carlos Park Bonita Springs Esb Jr Football Associatio | Recreation & Sports | $140K | $33K |
| 42 | Little Leage Baseball INC | Recreation & Sports | $126K | $103K |
| 43 | Florida Everblades Figure Skating Club INC | Recreation & Sports | $117K | $64K |
| 44 | Community Helping Hands INC | Education | $112K | $521K |
| 45 | College of Life Foundation INC | Unclassified | $105K | $622K |
| 46 | San Carlos Park Scorpion Soccer Club INC | Recreation & Sports | $104K | $157K |
| 47 | Cross Angle Ministries INC | Religion-Related | $99K | $235K |
| 48 | Friends of Koreshan State Park INC | Human Services | $96K | $150K |
| 49 | Wayne L Laufer Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $95K | $60K |
| 50 | Happen 365 INC | Human Services | $94K | $11K |
| 51 | The Healthy Earth Organization INC | Environment | $89K | $3K |
| 52 | His Word Ministries | Religion-Related | $88K | $15K |
| 53 | Wayne & Donna Smith Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $88K | $80K |
| 54 | Believe N Books INC | Education | $85K | $15K |
| 55 | Rotary Club of Estero Foundation INC | Philanthropy, Voluntarism & Grantmaking | $68K | $48K |
| 56 | Lets Talk Dementia | Arts, Culture & Humanities | $67K | $11K |
| 57 | Florida Everblades Fan Club of Swfl INC | Recreation & Sports | $66K | $58K |
| 58 | International Special Education Services INC | Education | $65K | $93K |
| 59 | Ellis Family Foundation | Philanthropy, Voluntarism & Grantmaking | $58K | $39K |
| 60 | Estero Council of Community Leaders | Community Improvement & Capacity Building | $56K | $100K |
| 61 | Douglas J & Elsie M Bailey Memorial Foundation | Philanthropy, Voluntarism & Grantmaking | $54K | $312K |
| 62 | Brodie Foundation | Philanthropy, Voluntarism & Grantmaking | $50K | $321K |
| 63 | Bregman Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $40K | $88K |
| 64 | Hawkins Foundation INC | Unclassified | $39K | $170K |
| 65 | Imburgia Foundation INC | Philanthropy, Voluntarism & Grantmaking | $37K | $82K |
| 66 | Edison Fairs Incorporated | Education | $34K | $24K |
| 67 | The Grit and Grace Project INC | Religion-Related | $29K | $23K |
| 68 | Southwest Florida Brew Crafters | Education | $25K | $26K |
| 69 | Gladiator Flag Football INC | Recreation & Sports | $24K | $24K |
| 70 | Lee County Wildcats | Recreation & Sports | $20K | $93 |
| 71 | Layden Family Foundation | Philanthropy, Voluntarism & Grantmaking | $12K | $491K |
| 72 | Stacy L and David W Schulz Family Foundation | Unclassified | $12K | $306K |
| 73 | Compassionate Care 4 You INC | Human Services | $7K | $228 |
| 74 | Patterson-wesselman-simpson Foundation | Philanthropy, Voluntarism & Grantmaking | $2K | $37K |
| 75 | Engine 4 Ladder 15 Family Fund INC | Public Safety, Disaster Preparedness & Relief | $105 | $218K |
| 76 | Reeves Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1 | $1 |
| 77 | Rotary International | Unclassified | $0 | $0 |
| 78 | Florida Government Finance Officers Association INC | Community Improvement & Capacity Building | $0 | $0 |
| 79 | Top Gun All Star Cheerleading Booster Club INC | Recreation & Sports | $0 | $0 |
| 80 | Friends of South County Regional Library INC | Unclassified | $0 | $0 |
| 81 | Foundation for Respect INC | Human Services | $0 | $0 |
| 82 | Travis Jason Long Firefighter Memorial Fund INC | Education | $0 | $0 |
| 83 | Brooks Fishing Club | Recreation & Sports | $0 | $0 |
| 84 | National Slovak Society of the USA | Unclassified | $0 | $0 |
| 85 | Iglesia Cristiana Peniel de Bdc INC | Religion-Related | $0 | $0 |
| 86 | Pi Mu Chapter of Chi Omega House Corporation INC | Education | $0 | $0 |
| 87 | Sunrise World Hope INC | Religion-Related | $0 | $0 |
| 88 | Lindsey Graham Ministries INC | Unclassified | $0 | $0 |
| 89 | Grandezza Girlfriends | Recreation & Sports | $0 | $0 |
| 90 | Faces of the World INC | Arts, Culture & Humanities | $0 | $0 |
| 91 | Fk Love Foundation INC | Human Services | $0 | $0 |
| 92 | Rotary International District 6960 Foundation INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 93 | Good Days Foundation INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 94 | Valor Christian Academy INC | Education | $0 | $0 |
| 95 | Kingdom Capital | Religion-Related | $0 | $0 |
| 96 | Stryk Out Cancer INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 97 | Good Faith Foundation INC | Human Services | $0 | $0 |
| 98 | Cascades at Estero Bocce Club | Recreation & Sports | $0 | $0 |
| 99 | Calusa Tribe Lacrosse Club INC | Youth Development | $0 | $0 |
| 100 | Burn Ft Myers Baseball | Recreation & Sports | $0 | $0 |