| 1 | Tidalhealth Nanticoke INC | Health Care | $201.4M | $163.5M |
| 2 | Sussex Montessori School INC | Education | $7.3M | $21.1M |
| 3 | Delmarva Teen Challenge INC | Human Services | $5.0M | $6.7M |
| 4 | Seaford Volunteer Fire Department INC | Public Safety, Disaster Preparedness & Relief | $3.5M | $11.1M |
| 5 | Nanticoke Senior Center INC | Unclassified | $915K | $1.6M |
| 6 | Love INC of Mid Delmarva INC | Religion-Related | $914K | $1.1M |
| 7 | American Legion | Unclassified | $521K | $421K |
| 8 | Seaford District Library | Unclassified | $480K | $2.9M |
| 9 | Delaware Strong Families INC | Religion-Related | $466K | $294K |
| 10 | American Legion | Unclassified | $385K | $194K |
| 11 | Curiosity Service Foundation INC | Human Services | $376K | $511K |
| 12 | Cross Christian Academy INC | Education | $305K | $819K |
| 13 | Better Homes of Seaford INC | Unclassified | $270K | $5.9M |
| 14 | Seaford Lodge No 1728 Loyal Order of Moose | Unclassified | $259K | $637K |
| 15 | National Rural Letter Carriers Association | Unclassified | $243K | $405K |
| 16 | Seaford Historical Society | Unclassified | $234K | $2.9M |
| 17 | Little League Baseball INC | Unclassified | $197K | $309K |
| 18 | Benevolent & Protective Order of Elks of the USA | Unclassified | $169K | $231K |
| 19 | Seaford Swimming Pool Assoc INC | Recreation & Sports | $162K | $115K |
| 20 | Western Sussex Chamber of Commerce | Unclassified | $131K | $68K |
| 21 | Her Care Clinic INC | Human Services | $129K | $74K |
| 22 | Trinity Foundati0n | Human Services | $119K | $153K |
| 23 | Delaware Family Policy Council | Public & Societal Benefit | $109K | $65K |
| 24 | Delaware School Nutrition Association | Food, Agriculture & Nutrition | $100K | $57K |
| 25 | Fisher of Men Foundation | Unclassified | $95K | $404K |
| 26 | Tidemark Fcu Foundation INC | Philanthropy, Voluntarism & Grantmaking | $93K | $149K |
| 27 | Veterans of Foreign Wars Department of Delaware | Public & Societal Benefit | $83K | $21K |
| 28 | Seaford Community Concert Association INC | Arts, Culture & Humanities | $75K | $188K |
| 29 | Seaford Community Swim Center INC | Recreation & Sports | $67K | $30K |
| 30 | Nanticoke River Yacht Club | Unclassified | $59K | $221K |
| 31 | Odd Fellows Cemetery INC | Unclassified | $55K | $557K |
| 32 | Seipp Charitable Tr | Religion-Related | $54K | $155K |
| 33 | Seaford School District Scholarship Foundation | Education | $52K | $989K |
| 34 | Nanticoke River Watershed Conservan Cy | Environment | $52K | $753K |
| 35 | Square One de INC | Human Services | $40K | $208K |
| 36 | Degrafft Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $34K | $31K |
| 37 | Steps for Hope INC | Mental Health & Crisis Intervention | $23K | $638K |
| 38 | Soroptimist International of the Americas INC | Crime & Legal-Related | $14K | $4K |
| 39 | Seaford Nylon Employees Council INC | Unclassified | $12K | $291K |
| 40 | Open Hearts Open Minds Counseling Ministries INC | Religion-Related | $1 | $1 |
| 41 | Banning Leadership Foundation | Human Services | $1 | $6K |
| 42 | Clarence St. Church of God | Unclassified | $0 | $0 |
| 43 | First Haitian Baptist Church of Seaford Delaware | Unclassified | $0 | $0 |
| 44 | Eastern Shore Afram Festival | Arts, Culture & Humanities | $0 | $0 |
| 45 | Divine Destiny Church of God Mission | Unclassified | $0 | $0 |
| 46 | Bethel Worship Center | Religion-Related | $0 | $0 |
| 47 | Gtw Ministries Incc | Religion-Related | $0 | $0 |
| 48 | Noble Venture INC | Religion-Related | $0 | $0 |
| 49 | Delaware Trapshooting Association INC | Unclassified | $0 | $0 |
| 50 | American Postal Workers Union | Employment | $0 | $0 |
| 51 | Veterans of Foreign Wars Auxiliary Department of Delaware | Unclassified | $0 | $0 |
| 52 | Rainbow Daycare and Preschool Seaford Wesleyan Church | Unclassified | $0 | $0 |
| 53 | First Baptist Church of Seaford INC | Unclassified | $0 | $0 |
| 54 | Independent Order of Odd Fellows | Unclassified | $0 | $0 |
| 55 | Family Motor Coach Association | Unclassified | $0 | $0 |
| 56 | Soul Saving Family Restoration Center INC | Religion-Related | $0 | $0 |
| 57 | Kingdom Empowerment Christian Church | Religion-Related | $0 | $0 |
| 58 | Immanuel House of Praise | Religion-Related | $0 | $0 |
| 59 | Cool Branch Home Owners Association | Housing & Shelter | $0 | $0 |
| 60 | Haitian Sanctified Church of God | Unclassified | $0 | $0 |
| 61 | East Coast Evangelizing Fellowship | Religion-Related | $0 | $0 |
| 62 | Nanticoke Amateur Radio Club INC | Education | $0 | $0 |
| 63 | Plumbers and Pipefitters Local Union No 782 Joint Apprenticeship | Unclassified | $0 | $0 |
| 64 | New Coverdale Outreach Mission INC | Food, Agriculture & Nutrition | $0 | $0 |
| 65 | Paws for Rescue INC | Animal-Related | $0 | $0 |
| 66 | Seaford Youth Football | Recreation & Sports | $0 | $0 |
| 67 | Feral Feline Society | Animal-Related | $0 | $0 |
| 68 | Sussex County Animal Association | Animal-Related | $0 | $0 |
| 69 | All Walks of Life Outreach Ministries | Religion-Related | $0 | $0 |
| 70 | Primitive Baptist Church | Unclassified | $0 | $0 |
| 71 | Integrated History Project - Ihp | Science & Technology | $0 | $0 |
| 72 | Delaware Nanticoke Rotary Foundation INC | Human Services | $0 | $0 |
| 73 | Harvest Time Ministry | Religion-Related | $0 | $0 |
| 74 | Encounter Praize and Worship Center INC | Religion-Related | $0 | $0 |
| 75 | Nanticoke Hope INC | Youth Development | $0 | $0 |
| 76 | Marine Corps League | Unclassified | $0 | $0 |
| 77 | Sussex Community Gospel Ministries INC | Religion-Related | $0 | $0 |
| 78 | Seaford Ffa Alumni Association | Education | $0 | $0 |
| 79 | Woodbridge Pride Cheerleading | Recreation & Sports | $0 | $0 |
| 80 | Seaford Tomorrow INC | Public & Societal Benefit | $0 | $0 |
| 81 | Kiwanis International INC | Unclassified | $0 | $0 |
| 82 | Mt Olivet United Methodist Church | Unclassified | $0 | $0 |
| 83 | Leon Williams Revivals INC | Religion-Related | $0 | $0 |
| 84 | International Association of Lions Clubs | Unclassified | $0 | $0 |
| 85 | First Church of the Nazarene of Seaford Delaware | Unclassified | $0 | $0 |
| 86 | Grace Baptist Church-seaford | Unclassified | $0 | $0 |
| 87 | Seaford Chapter 1384 Women of the Moose | Unclassified | $0 | $0 |
| 88 | Christ Lutheran Church | Unclassified | $0 | $0 |
| 89 | Tidalhealth Physician Network INC | Health Care | $0 | $0 |
| 90 | Atlanta Road Alliance Church | Unclassified | $0 | $0 |
| 91 | Delaware State Fire Chiefs Assoc | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 92 | Order of the Eastern Star of Delaware | Unclassified | $0 | $0 |
| 93 | Friends of the Seaford District Library INC | Unclassified | $0 | $0 |
| 94 | Holly Shores Property Owners Association INC | Community Improvement & Capacity Building | $0 | $0 |
| 95 | Kiwanis Foundation of the Kiwanis Club of Seaford INC | Unclassified | $0 | $0 |
| 96 | Rotary International | Unclassified | $0 | $0 |
| 97 | Seaford-blades Associated Charities INC | Unclassified | $0 | $0 |
| 98 | Nanticoke Sportsmens Club INC | Recreation & Sports | $0 | $0 |
| 99 | Grace Tabernacle of Deliverance Church INC | Religion-Related | $0 | $0 |
| 100 | Citadel of Hope Deliverance Ministries INC | Religion-Related | $0 | $0 |