| 1 | Oakwood University INC | Unclassified | $77.1M | $106.7M |
| 2 | Alpha Foundation INC | Philanthropy, Voluntarism & Grantmaking | $74.2M | $47.1M |
| 3 | Huntsville Rehabilitation Foundation | Employment | $62.7M | $59.0M |
| 4 | Randolph School | Education | $61.1M | $74.1M |
| 5 | Hudson-alpha Institute for Biotechnology | Science & Technology | $53.8M | $205.8M |
| 6 | Food Bank of North Alabama | Food, Agriculture & Nutrition | $39.1M | $21.5M |
| 7 | University of Alabama Huntsville Foundation | Unclassified | $34.2M | $131.7M |
| 8 | Aids Action Coalition of Huntsville | Diseases, Disorders & Medical Disciplines | $33.3M | $20.2M |
| 9 | Community Foundation of Greater Huntsville | Philanthropy, Voluntarism & Grantmaking | $29.5M | $66.3M |
| 10 | Wellstone INC | Mental Health & Crisis Intervention | $25.9M | $27.2M |
| 11 | Redstone Village | Housing & Shelter | $24.7M | $73.6M |
| 12 | Erc INC Veba Tr | Mutual & Membership Benefit | $23.4M | $2K |
| 13 | U S Space & Rocket Center Education Foundation | Human Services | $22.2M | $21.1M |
| 14 | The Valley Foundation | Education | $15.2M | $23.8M |
| 15 | Hudsonalpha Foundation | Education | $14.3M | $65.6M |
| 16 | The Huntsville Hospital Foundation INC | Health Care | $14.1M | $50.3M |
| 17 | Ability Plus INC | Human Services | $12.6M | $7.0M |
| 18 | Arc of Madison County INC | Unclassified | $11.6M | $15.8M |
| 19 | National Childrens Advocacy Center INC | Unclassified | $11.2M | $8.9M |
| 20 | Young Mens Christian Association of Metropolitan Huntsville Alabama | Human Services | $10.8M | $22.9M |
| 21 | Downtown Rescue Mission INC | Housing & Shelter | $10.7M | $20.1M |
| 22 | Central North Alabama Health Services INC | Health Care | $10.2M | $8.8M |
| 23 | Ascte Foundation | Education | $9.7M | $63.8M |
| 24 | Huntsville Madison County Botanical Garden Society INC | Environment | $9.3M | $23.2M |
| 25 | Comn Action Partnership Huntsville Madison & Limestone Counties INC | Human Services | $8.1M | $1.2M |
| 26 | Boys and Girls Club of North Alabama | Youth Development | $8.0M | $19.7M |
| 27 | Drm Title Holding Corporation | Community Improvement & Capacity Building | $7.5M | $0 |
| 28 | Happi Health | Health Care | $6.1M | $3.4M |
| 29 | The Land Trust of North Alabama INC | Environment | $6.1M | $52.6M |
| 30 | Chamber of Commerce-huntsville-madison County | Unclassified | $6.0M | $6.6M |
| 31 | Valley Hill Country Club | Unclassified | $5.9M | $6.2M |
| 32 | North Alabama Educators Credit Union | Public & Societal Benefit | $5.7M | $132.7M |
| 33 | United Cerebral Palsy of Huntsville and Tennessee Valley INC | Unclassified | $5.5M | $2.7M |
| 34 | His Way Recovery Center | Housing & Shelter | $5.4M | $8.6M |
| 35 | Huntsville Museum Association INC | Arts, Culture & Humanities | $5.2M | $14.0M |
| 36 | Broadway Theatre League of Huntsville INC | Arts, Culture & Humanities | $5.0M | $2.3M |
| 37 | A New Leash on Life | Animal-Related | $4.5M | $5.1M |
| 38 | Habitat for Humanity International INC | Housing & Shelter | $4.1M | $9.4M |
| 39 | Huntsville Museum of Art | Arts, Culture & Humanities | $3.9M | $898K |
| 40 | Lincoln Village Preservation Corporation | Housing & Shelter | $3.6M | $13.8M |
| 41 | Propst Foundation | Philanthropy, Voluntarism & Grantmaking | $3.1M | $7.9M |
| 42 | Crisis Services of North Alabama | Unclassified | $3.1M | $1.9M |
| 43 | Arts Council INC | Arts, Culture & Humanities | $2.8M | $1.8M |
| 44 | United Way of Madison County INC | Philanthropy, Voluntarism & Grantmaking | $2.8M | $2.6M |
| 45 | The@jane K Lowe Charitable Foundation | Unclassified | $2.8M | $25.6M |
| 46 | Montessori School of Huntsville | Unclassified | $2.7M | $2.1M |
| 47 | The Huntsville and Madison County Railroad Authority | Unclassified | $2.7M | $7.2M |
| 48 | Huntsville Symphony Orchestra Association | Arts, Culture & Humanities | $2.7M | $1.1M |
| 49 | Nafasi Fund | Youth Development | $2.5M | $3.8M |
| 50 | Still Serving Vets | Public & Societal Benefit | $2.5M | $1.5M |
| 51 | National Speleological Society | Recreation & Sports | $2.4M | $13.8M |
| 52 | Riley Behavioral and Educational Center | Education | $2.4M | $3.0M |
| 53 | Huntsville-madison County Senior Center INC | Unclassified | $2.2M | $2.3M |
| 54 | Dynetics INC Employee Health and Welfare Plan | Mutual & Membership Benefit | $2.2M | $1.1M |
| 55 | North Alabama Center for Educational Excellence INC | Education | $2.1M | $0 |
| 56 | Huntsville Area Association of Realtors INC | Unclassified | $2.1M | $4.1M |
| 57 | Liberty Learning Foundation | Education | $2.1M | $464K |
| 58 | Enrichment Center INC | Mental Health & Crisis Intervention | $1.9M | $2.6M |
| 59 | Greater Huntsville Humane Society | Animal-Related | $1.9M | $2.7M |
| 60 | Huntsville Sports Commission INC | Recreation & Sports | $1.9M | $252K |
| 61 | Strain Foundation | Unclassified | $1.9M | $5.1M |
| 62 | Huntsville Symphony Orchestra Foundation | Philanthropy, Voluntarism & Grantmaking | $1.8M | $3.4M |
| 63 | Heals INC | Health Care | $1.8M | $1.8M |
| 64 | Huntsville-madison County Chamber of Commerce Foundation | Community Improvement & Capacity Building | $1.8M | $2.3M |
| 65 | Burritt Museum Association INC | Arts, Culture & Humanities | $1.8M | $1.5M |
| 66 | Harris Home for Children | Unclassified | $1.8M | $2.2M |
| 67 | Huntsville Botanical Garden Foundation INC | Environment | $1.8M | $2.6M |
| 68 | Neighborhood Concepts INC | Housing & Shelter | $1.7M | $17.0M |
| 69 | The Catalyst Center for Business & Entrepreneurship | Community Improvement & Capacity Building | $1.7M | $626K |
| 70 | Madison County 310 Board | Unclassified | $1.7M | $3.8M |
| 71 | Beard Young Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.6M | $3.9M |
| 72 | Second Mile Development INC | Human Services | $1.6M | $1.4M |
| 73 | Marshall Child Development Center INC | Education | $1.6M | $330K |
| 74 | The Rotary Club of Huntsville Foundation | Education | $1.5M | $2.2M |
| 75 | Valley Garden Foundation INC | Unclassified | $1.5M | $738K |
| 76 | Center for Rural Enterprise and Environmental Justice | Environment | $1.5M | $3.7M |
| 77 | Housing Foundation of Huntsville INC | Unclassified | $1.5M | $1.0M |
| 78 | Vine Pastoral Counseling Center INC | Religion-Related | $1.5M | $2.9M |
| 79 | Village of Promise Incorporated | Human Services | $1.5M | $198K |
| 80 | Huntsville Madison County Builders Association INC | Unclassified | $1.4M | $2.6M |
| 81 | United Cerebral Palsy of Ala | Diseases, Disorders & Medical Disciplines | $1.4M | $519K |
| 82 | Russel Hill Cancer Foundation INC | Unclassified | $1.4M | $2.3M |
| 83 | North Alabama Hockey Association INC | Arts, Culture & Humanities | $1.3M | $452K |
| 84 | Better Business Bureau of North Alabama INC | Unclassified | $1.3M | $839K |
| 85 | Drake State Technical College Foundation INC | Unclassified | $1.3M | $1.5M |
| 86 | Generosity Foundation | Philanthropy, Voluntarism & Grantmaking | $1.3M | $2.0M |
| 87 | Eighth Street Community | Human Services | $1.3M | $1.2M |
| 88 | Free 2 Teach Foundation | Education | $1.2M | $1.3M |
| 89 | Rocket City Scholarship Granting Organization INC | Education | $1.2M | $2.3M |
| 90 | Ashakiran INC | Human Services | $1.2M | $1.4M |
| 91 | Huntsville Inner City Learningcenter INC | Education | $1.2M | $4.1M |
| 92 | Communication Workers of America | Unclassified | $1.2M | $937K |
| 93 | Fantasy Playhouse Childrens Theater | Arts, Culture & Humanities | $1.2M | $3.8M |
| 94 | Singing River Trail | Community Improvement & Capacity Building | $1.2M | $532K |
| 95 | Huntsville Swim Association | Unclassified | $1.2M | $609K |
| 96 | Mission Driven Ministries | Religion-Related | $1.1M | $655K |
| 97 | Community Ballet Association of Huntsville INC | Unclassified | $1.1M | $1.2M |
| 98 | Huntsville Dream Center INC | Philanthropy, Voluntarism & Grantmaking | $1.1M | $916K |
| 99 | Rose of Sharon INC | Food, Agriculture & Nutrition | $1.1M | $131K |
| 100 | The@museum of Information Explosion | Arts, Culture & Humanities | $1.1M | $4.4M |