| 1 | Mayo Clinic Group Return Rochester, MN | $14.9B | $17.9B |
| 2 | Thrivent Financial for Lutherans Minneapolis, MN | $11.8B | $118.0B |
| 3 | Mayo Clinic Rochester, MN | $7.9B | $26.7B |
| 4 | Ucare Minnesota Minneapolis, MN | $6.3B | $1.5B |
| 5 | Allina Health System Minneapolis, MN | $5.9B | $6.0B |
| 6 | Fairview Health Services Minneapolis, MN | $5.3B | $6.5B |
| 7 | Healthpartners INC Minneapolis, MN | $3.2B | $1.7B |
| 8 | Hmo Minnesota Saint Paul, MN | $3.1B | $1.4B |
| 9 | Park Nicollet St. Louis Park, MN | $2.2B | $1.6B |
| 10 | Medica Health Plans Minnetonka, MN | $1.8B | $971.7M |
| 11 | Hennepin Healthcare System INC Minneapolis, MN | $1.7B | $816.7M |
| 12 | Group Health INC Bloomington, MN | $1.5B | $1.7B |
| 13 | Stratacor Minneapolis, MN | $1.2B | $468.6M |
| 14 | Childrens Health Care Minneapolis, MN | $1.2B | $1.9B |
| 15 | Regions Hospital Bloomington, MN | $1.1B | $1.2B |
| 16 | St. Cloud Hospital Saint Cloud, MN | $1.1B | $1.4B |
| 17 | North Memorial Health Care Robbinsdale, MN | $998.7M | $713.0M |
| 18 | University of Minnesota Physicians Minneapolis, MN | $903.0M | $286.8M |
| 19 | Smdc Medical Center Duluth, MN | $796.4M | $1.1B |
| 20 | National Marrow Donor Program Minneapolis, MN | $666.7M | $402.7M |
| 21 | Centracare Health System Saint Cloud, MN | $577.8M | $1.2B |
| 22 | St. Marys Medical Center Duluth, MN | $563.8M | $1.0B |
| 23 | University of Minnesota Foundation Minneapolis, MN | $524.0M | $4.9B |
| 24 | Healtheast St. Johns Hospital Minneapolis, MN | $521.8M | $193.7M |
| 25 | University of St. Thomas St. Paul, MN | $513.6M | $1.9B |
| 26 | Ecmc Group INC Minneapolis, MN | $501.3M | $5.7B |
| 27 | Delta Dental of Minnesota Minneapolis, MN | $497.1M | $111.5M |
| 28 | Wings Financial Credit Union Apple Valley, MN | $476.1M | $9.4B |
| 29 | The Travelers Companies INC St. Paul, MN | $472.2M | $24.4M |
| 30 | Ridgeview Medical Center Waconia, MN | $407.1M | $402.1M |
| 31 | Gillette Childrens Specialty Health Care Saint Paul, MN | $396.6M | $514.2M |
| 32 | Essentia Health Duluth, MN | $369.9M | $869.7M |
| 33 | Centracare Clinic Saint Cloud, MN | $319.1M | $62.7M |
| 34 | Second Harvest Heartland Brooklyn Park, MN | $309.2M | $123.1M |
| 35 | Olmsted Medical Center Rochester, MN | $304.8M | $311.5M |
| 36 | Maple Grove Hospital Corporation Maple Grove, MN | $302.6M | $151.1M |
| 37 | St. Olaf College Northfield, MN | $299.9M | $1.2B |
| 38 | St. Joseph S Medical Center Brainerd, MN | $292.1M | $438.5M |
| 39 | Carleton College Northfield, MN | $279.0M | $1.9B |
| 40 | Duluth Clinic LTD Duluth, MN | $277.6M | $137.3M |
| 41 | International Operating Engineers Union 49 Health and Welfare Fund Bloomington, MN | $270.6M | $273.0M |
| 42 | St. Lukes Hospital of Duluth Duluth, MN | $270.4M | $536.1M |
| 43 | Blaze Credit Union Falcon Hgts, MN | $268.0M | $4.3B |
| 44 | Educational Credit Management Corporation Minneapolis, MN | $265.0M | $209.1M |
| 45 | Thrivent Charitable Impact & Investing Minneapolis, MN | $264.4M | $939.7M |
| 46 | Carpenters & Joiners Welfare Fund Bloomington, MN | $261.9M | $349.6M |
| 47 | Workers Compensation Reinsurance Association Saint Paul, MN | $260.6M | $3.8B |
| 48 | Scholarship America INC Minneapolis, MN | $259.9M | $194.4M |
| 49 | Connexus Energy Ramsey, MN | $259.0M | $493.8M |
| 50 | St. Francis Regional Medical Center Minneapolis, MN | $239.3M | $276.7M |