| 1 | Johns Hopkins University Baltimore, MD | $10.5B | $23.0B |
| 2 | Kaiser Foundation Health Plan of the Mid Atlantic States INC Hyattsville, MD | $6.0B | $3.3B |
| 3 | The Johns Hopkins Hospital Baltimore, MD | $3.4B | $3.6B |
| 4 | A D F Community Outreach Foundation INC Mechanicsvlle, MD | $3.1B | $37.5M |
| 5 | Financial Industry Regulatory Authority INC Rockville, MD | $2.6B | $3.1B |
| 6 | University of Maryland Medical System Corporation Linthicum Heights, MD | $2.4B | $4.8B |
| 7 | Hh Medstar Health INC Columbia, MD | $2.1B | $473.5M |
| 8 | Howard Hughes Medical Institute Chevy Chase, MD | $2.0B | $29.5B |
| 9 | Washington Hospital Center Corporation Columbia, MD | $1.7B | $793.9M |
| 10 | Medstar-georgetown Medical Center INC Columbia, MD | $1.7B | $1.5B |
| 11 | Finra Regulation INC Rockville, MD | $1.4B | $94.1M |
| 12 | American Postal Workers Union Elkridge, MD | $1.3B | $445.7M |
| 13 | Sinai Hospital of Baltimore INC Baltimore, MD | $1.0B | $811.2M |
| 14 | Johns Hopkins All Childrens Hospital INC Baltimore, MD | $912.8M | $1.4B |
| 15 | Healthwell Foundation Germantown, MD | $911.5M | $918.2M |
| 16 | Adventist Healthcare INC Gaithersburg, MD | $909.8M | $1.6B |
| 17 | Johns Hopkins Bayview Medical Center INC Baltimore, MD | $805.6M | $459.3M |
| 18 | Neca Ibew Family Medical Care TR Fund Rockville, MD | $771.0M | $1.1B |
| 19 | The Johns Hopkins Health System Corporation Baltimore, MD | $711.5M | $2.2B |
| 20 | Holy Cross Health INC Silver Spring, MD | $709.0M | $1.1B |
| 21 | Jack and Nancy Dwyer Workforce Development Center INC Baltimore, MD | $696.1M | $904.2M |
| 22 | Board of Education of Montgomery County Employee Benefit Trust Fund Rockville, MD | $690.1M | $19.4M |
| 23 | Impactassets INC Bethesda, MD | $680.3M | $3.0B |
| 24 | Luminis Health Anne Arundel Medical Center INC Annapolis, MD | $672.1M | $1.1B |
| 25 | Lucy Webb Haynes National Training School for Deaconesses and Mission Baltimore, MD | $653.7M | $1.7B |
| 26 | Mercy Medical Center INC Baltimore, MD | $633.9M | $1.1B |
| 27 | Meritus Medical Center INC Hagerstown, MD | $633.6M | $911.6M |
| 28 | Greater Baltimore Medical Center Baltimore, MD | $629.2M | $901.3M |
| 29 | Henry M Jackson Foundation for the Advancement of Military Medicine Bethesda, MD | $628.9M | $321.6M |
| 30 | Franklin Square Hospital Center INC Baltimore, MD | $613.1M | $342.0M |
| 31 | Tidalhealth Peninsula Regional INC Salisbury, MD | $575.5M | $746.9M |
| 32 | Umsj Health System LLC Towson, MD | $568.0M | $406.6M |
| 33 | Southern Maryland Electric Cooperative INC Hughesville, MD | $542.5M | $1.2B |
| 34 | Baltimore Washington Medical Center INC Linthicum Heights, MD | $494.5M | $546.0M |
| 35 | Johns Hopkins Medical Services Corporation Baltimore, MD | $490.3M | $2.9M |
| 36 | Dimensions Health Corporation Linthicum Heights, MD | $463.7M | $729.6M |
| 37 | Union Memorial Hospital Baltimore, MD | $446.2M | $257.1M |
| 38 | Frederick Health Hospital INC Frederick, MD | $425.5M | $665.6M |
| 39 | National Automatic Sprinkler Industry Welfare Fund Landover, MD | $397.5M | $787.7M |
| 40 | Suburban Hospital Incorporated Baltimore, MD | $394.3M | $694.3M |
| 41 | Upper Chesapeake Medical Center INC Linthicum Heights, MD | $389.1M | $849.1M |
| 42 | Loyola University Maryland INC Baltimore, MD | $368.2M | $751.8M |
| 43 | Medstar Health INC Columbia, MD | $363.6M | $3.4B |
| 44 | Lifebridge Health INC Owings Mills, MD | $358.9M | $1.7B |
| 45 | United States Pharmacopeial Convention INC Rockville, MD | $357.7M | $788.7M |
| 46 | Cystic Fibrosis Foundation Bethesda, MD | $355.8M | $5.0B |
| 47 | Johns Hopkins University Baltimore, MD | $349.7M | $216.1M |
| 48 | NFL Player Supplemental Disability Plan Trust Baltimore, MD | $349.5M | $92.3M |
| 49 | Howard County General Hospital INC Baltimore, MD | $333.9M | $442.9M |
| 50 | Johns Hopkins Community Physicians INC Baltimore, MD | $333.4M | $109.1M |