| 1 | A Mainehealth Hcsr Portland, ME | $4.1B | $4.2B |
| 2 | Eastern Maine Healthcare Systems Brewer, ME | $1.1B | $931.4M |
| 3 | Martins Point Generations Advantage INC Portland, ME | $745.8M | $221.8M |
| 4 | Mainegeneral Health Augusta, ME | $743.2M | $682.2M |
| 5 | Jackson Laboratory Bar Harbor, ME | $652.5M | $1.6B |
| 6 | Maine Education Association Benefits Trust Augusta, ME | $591.8M | $170.0M |
| 7 | Martins Point Health Care INC Portland, ME | $550.1M | $575.9M |
| 8 | Central Maine Medical Center Lewiston, ME | $513.4M | $265.3M |
| 9 | Eastern Maine Healthcare Systems Brewer, ME | $440.7M | $929.3M |
| 10 | President & Trustees of Colby College Waterville, ME | $379.6M | $2.4B |
| 11 | Bowdoin College Brunswick, ME | $369.8M | $3.2B |
| 12 | Mercy Hospital Portland, ME | $328.2M | $259.7M |
| 13 | Maine Community Health Options New Gloucestr, ME | $303.8M | $124.3M |
| 14 | University of New England Biddeford, ME | $303.4M | $788.8M |
| 15 | St. Joseph Hospital Bangor, ME | $238.2M | $86.5M |
| 16 | St. Marys Regional Medical Center Lewiston, ME | $236.2M | $135.7M |
| 17 | Employees of Municipal & Other Pub- Lic Employers of Me Health Ins TR Augusta, ME | $213.4M | $120.4M |
| 18 | York Hospital York, ME | $205.4M | $117.1M |
| 19 | President and Trustees of Bates College Lewiston, ME | $192.8M | $887.4M |
| 20 | Eastern Maine Healthcare Systems Presque Isle, ME | $168.5M | $81.4M |
| 21 | Redington-fairview General Hospital Skowhegan, ME | $158.9M | $148.6M |
| 22 | Maine Community Foundation INC Ellsworth, ME | $138.8M | $807.6M |
| 23 | New England Life Care INC Scarborough, ME | $135.2M | $62.1M |
| 24 | Maine Coast Regional Health Facili DBA Northern Light Maine Coast Hos Ellsworth, ME | $117.8M | $80.8M |
| 25 | Mount Desert Island Hospital Bar Harbor, ME | $114.7M | $106.0M |
| 26 | Nordx Scarborough, ME | $106.8M | $46.7M |
| 27 | Maine Veterans Home Augusta, ME | $106.7M | $172.6M |
| 28 | Good Sheperd Food Bank Auburn, ME | $104.5M | $44.8M |
| 29 | Penobscot Community Health Center Bangor, ME | $102.9M | $79.1M |
| 30 | Spurwink Services Incorporated Portland, ME | $96.4M | $51.6M |
| 31 | Eastern Maine Healthcare Systems Bangor, ME | $87.9M | $115.1M |
| 32 | Unity Environmental University New Gloucester, ME | $86.7M | $107.2M |
| 33 | Husson University Bangor, ME | $86.2M | $152.9M |
| 34 | Maine Guaranteed Access Reinsurance Association Portland, ME | $79.8M | $87.0M |
| 35 | John F Murphy Homes INC Auburn, ME | $79.2M | $94.8M |
| 36 | Eastern Maine Healthcare Systems Waterville, ME | $76.9M | $49.2M |
| 37 | Eastern Maine Healthcare Systems Dovr Foxcroft, ME | $73.7M | $48.8M |
| 38 | Northern Maine Medical Center Fort Kent, ME | $70.6M | $105.4M |
| 39 | Penquis C a P INC Bangor, ME | $66.5M | $52.2M |
| 40 | Central Maine Healthcare Corporation Lewiston, ME | $66.5M | $141.8M |
| 41 | Down East Community Hospital Machias, ME | $64.8M | $55.8M |
| 42 | Eastern Maine Healthcare Systems Pittsfield, ME | $62.5M | $87.3M |
| 43 | University of Maine Foundation Orono, ME | $60.4M | $458.3M |
| 44 | Bridgton Hospital Bridgton, ME | $59.0M | $35.6M |
| 45 | Androscoggin Home Health Services INC Lewiston, ME | $58.7M | $42.8M |
| 46 | Houlton Regional Hospital Houlton, ME | $58.4M | $30.8M |
| 47 | Rumford Hospital Rumford, ME | $57.9M | $20.5M |
| 48 | Sweetser Saco, ME | $54.7M | $52.1M |
| 49 | Trustees of St. Josephs College Standish, ME | $54.4M | $64.3M |
| 50 | Permanent Archive Fund Biddeford, ME | $51.0M | $36.1M |