| 401 | Museum of Modern Art | New York, New York | $2.6B | $324.7M | $633.5M |
| 402 | Samaritans Purse | Boone, North Carolina | $2.6B | $1.8B | $2.3B |
| 403 | University of Oregon Foundation | Eugene, Oregon | $2.6B | $302.3M | $381.4M |
| 404 | Kaiser Foundation Health Plan of Colorado | Aurora, Colorado | $2.6B | $4.5B | $5.2B |
| 405 | Metroplus Health Plan INC | New York, New York | $2.6B | $4.9B | $4.9B |
| 406 | Sisters of Charity of Leavenworth Health System INC | Salt Lake Cty, Utah | $2.6B | $990.7M | $1.0B |
| 407 | Sarofim Foundation | Houston, Texas | $2.6B | $0 | $567.2M |
| 408 | Fidelity Non-profit Management Foundation | Boston, Massachusetts | $2.6B | $258.9M | $1.0B |
| 409 | Loyola University of Chicago | Chicago, Illinois | $2.6B | $1.1B | $1.7B |
| 410 | Gerson Bakar Foundation | San Francisco, California | $2.5B | $0 | $230.5M |
| 411 | Providence St. Joseph Health | Renton, Washington | $2.5B | $24.0M | $24.0M |
| 412 | Parkview Health System INC | Fort Wayne, Indiana | $2.5B | $1.2B | $1.8B |
| 413 | Claremont McKenna College | Claremont, California | $2.5B | $233.8M | $612.3M |
| 414 | John S and James L Knight Foundation INC | Miami, Florida | $2.5B | $0 | $675.1M |
| 415 | Thomas Jefferson University Hospital | Philadelphia, Pennsylvania | $2.5B | $2.6B | $2.6B |
| 416 | Childrens Medical Center Foundation | Dallas, Texas | $2.5B | $339.0M | $339.1M |
| 417 | Childrens Hospital of Wisconsin INC | Milwaukee, Wisconsin | $2.5B | $1.0B | $1.1B |
| 418 | Nc State Investment Fund INC | Raleigh, North Carolina | $2.5B | $304.3M | $1.3B |
| 419 | Childrens Hospital Medical Center of Akron | Akron, Ohio | $2.5B | $1.5B | $2.7B |
| 420 | Houston Endowment INC | Houston, Texas | $2.5B | $0 | $427.4M |
| 421 | Gothic Hsp Corporation | Durham, North Carolina | $2.5B | $490.2M | $490.2M |
| 422 | Sutter Bay Medical Foundation | Sacramento, California | $2.5B | $4.1B | $4.1B |
| 423 | Cook Childrens Medical Center | Fort Worth, Texas | $2.5B | $2.2B | $2.2B |
| 424 | Childrens Hospital INC | New Orleans, Louisiana | $2.5B | $737.3M | $1.3B |
| 425 | American University | Washington, District of Columbia | $2.5B | $937.1M | $1.3B |
| 426 | White Plains Medical Center | White Plains, New York | $2.5B | $1.2B | $1.2B |
| 427 | Valley Hospital INC | Paramus, New Jersey | $2.5B | $1.3B | $1.7B |
| 428 | Fordham University | Bronx, New York | $2.5B | $1.1B | $1.7B |
| 429 | Ewing Marion Kauffman Foundation | Kansas City, Missouri | $2.5B | $0 | $599.1M |
| 430 | College Board | New York, New York | $2.4B | $1.2B | $1.5B |
| 431 | Roper St. Francis Healthcare | Blue Ash, Ohio | $2.4B | $259.4M | $259.9M |
| 432 | Wesleyan University | Middletown, Connecticut | $2.4B | $449.0M | $937.5M |
| 433 | West Virginia University Hospitals INC | Morgantown, West Virginia | $2.4B | $2.5B | $2.5B |
| 434 | University of Maryland Foundation INC | Adelphi, Maryland | $2.4B | $77.1M | $77.1M |
| 435 | Childrens Hospital Colorado | Aurora, Colorado | $2.4B | $2.0B | $2.0B |
| 436 | Methodist Lebonheur Healthcare | Memphis, Tennessee | $2.4B | $439.8M | $439.8M |
| 437 | Trihealth INC | Cincinnati, Ohio | $2.4B | $354.3M | $390.9M |
| 438 | Commonwealth Scientific and Industrial Research Organization | San Francisco, California | $2.4B | $1.1B | $1.1B |
| 439 | Santa Barbara Cottage Hospital | Santa Barbara, California | $2.4B | $1.1B | $1.4B |
| 440 | Grady Memorial Hospital Corporation | Atlanta, Georgia | $2.4B | $2.7B | $2.7B |
| 441 | University of Georgia Foundation | Athens, Georgia | $2.4B | $327.3M | $558.6M |
| 442 | Raymond James Charitable Endowment Fund | St. Petersburg, Florida | $2.4B | $955.1M | $3.2B |
| 443 | Inatai Foundation | Seattle, Washington | $2.4B | $42.5M | $42.5M |
| 444 | President & Trustees of Colby College | Waterville, Maine | $2.4B | $379.6M | $526.2M |
| 445 | Trinity University | San Antonio, Texas | $2.3B | $338.7M | $472.4M |
| 446 | Mary Hitchcock Memorial Hospital | Lebanon, New Hampshire | $2.3B | $2.3B | $2.3B |
| 447 | Childrens Hospital | Washington, District of Columbia | $2.3B | $1.7B | $1.8B |
| 448 | K18n Foundation | Mountain View, California | $2.3B | -$124K | $124K |
| 449 | Valley Childrens Hospital | Madera, California | $2.3B | $966.4M | $1.7B |
| 450 | Combined Jewish Philanthropies of Greater Boston INC | Boston, Massachusetts | $2.3B | $317.7M | $518.9M |