| 1 | Inova Health Care Services | Health Care | $6.5B | $8.1B |
| 2 | Inova Health System Foundation | Health Care | $893.5M | $9.2B |
| 3 | George Mason University Foundation INC | Education | $288.7M | $498.7M |
| 4 | National Rifle Association of America | Civil Rights, Social Action & Advocacy | $217.1M | $137.1M |
| 5 | Riverside Research Institute | Medical Research | $189.3M | $171.5M |
| 6 | Claude Moore Charitable Foundation | Unclassified | $72.2M | $233.3M |
| 7 | The NRA Foundation INC | Crime & Legal-Related | $71.6M | $212.2M |
| 8 | Avixa INC | Unclassified | $67.8M | $56.3M |
| 9 | Pediatric Specialists of Virginia LLC | Health Care | $45.8M | $41.5M |
| 10 | The Community Foundation for Northern Virginia INC | Philanthropy, Voluntarism & Grantmaking | $40.4M | $107.4M |
| 11 | Sports Betting Alliance | Public & Societal Benefit | $31.6M | $15.4M |
| 12 | Armed Forces Communications and Electronics Association | Unclassified | $26.1M | $29.2M |
| 13 | Pathway Homes INC | Mental Health & Crisis Intervention | $24.2M | $31.7M |
| 14 | Coptic Orphans Support Association | International, Foreign Affairs & National Security | $23.9M | $67.0M |
| 15 | Society of Interventional Radiology | Unclassified | $23.5M | $16.1M |
| 16 | Palestinian American Medical Association | International, Foreign Affairs & National Security | $22.3M | $26.8M |
| 17 | Trinity Christian School of Fairfax | Education | $16.8M | $28.4M |
| 18 | Mason Korea LLC | Education | $15.7M | $11.4M |
| 19 | Country Club of Fairfax INC | Unclassified | $15.4M | $24.7M |
| 20 | American Association for Thoracic Surgery | Unclassified | $14.2M | $17.5M |
| 21 | International Town-country Club INC | Unclassified | $13.6M | $31.0M |
| 22 | American Legion | Unclassified | $13.3M | $3.6M |
| 23 | Hartwood Foundation INC | Human Services | $12.3M | $10.4M |
| 24 | The J127 Foundation | Housing & Shelter | $11.7M | $20.9M |
| 25 | United Help Ukraine | Human Services | $10.7M | $4.9M |
| 26 | Food for Others INC | Human Services | $10.7M | $10.3M |
| 27 | Hereditary Angioedema Association INC | Health Care | $10.2M | $21.9M |
| 28 | Community Living Alternatives Corporation | Human Services | $10.0M | $7.3M |
| 29 | National Pest Management Association INC | Unclassified | $9.9M | $10.8M |
| 30 | National Institute for Public Policy INC | Unclassified | $9.8M | $24.1M |
| 31 | Northern Virginia Assoc of Realtors Incorporated | Community Improvement & Capacity Building | $9.7M | $20.8M |
| 32 | Valentine Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $9.2M | $11.5M |
| 33 | Loyola Foundation INC | Unclassified | $9.1M | $32.3M |
| 34 | Fairfax Educational Foundation INC | Philanthropy, Voluntarism & Grantmaking | $9.0M | $134K |
| 35 | Jewish Community Center of Northern Virginia INC | Human Services | $8.6M | $14.0M |
| 36 | Northern Virginia Emergency Response System INC | Public Safety, Disaster Preparedness & Relief | $8.4M | $6.5M |
| 37 | Legal Services of Northern Virginia INC | Crime & Legal-Related | $8.1M | $4.7M |
| 38 | Facets Cares INC | Human Services | $8.0M | $4.6M |
| 39 | Afghan Health and Development Services | International, Foreign Affairs & National Security | $7.5M | $2.2M |
| 40 | American Council for Technology | Public & Societal Benefit | $7.3M | $7.5M |
| 41 | Society of Interventional Radiology Foundation | Medical Research | $7.2M | $8.0M |
| 42 | National Association of Landscape Professionals INC | Unclassified | $7.1M | $10.7M |
| 43 | Hae International | Medical Research | $6.6M | $7.1M |
| 44 | Brain Injury Association of America INC | Unclassified | $6.2M | $6.9M |
| 45 | Rfg Survey Association INC | Unclassified | $6.2M | $15.3M |
| 46 | Humane Society of Fairfax County INC | Animal-Related | $6.0M | $17.6M |
| 47 | American Village Communities INC | Housing & Shelter | $5.9M | $9.9M |
| 48 | American Village Communities INC | Housing & Shelter | $5.7M | $16.5M |
| 49 | Broadlands Association INC | Public & Societal Benefit | $5.7M | $4.9M |
| 50 | American Village Communities INC | Housing & Shelter | $5.6M | $10.6M |
| 51 | The Lamb Center | Environment | $5.6M | $15.6M |
| 52 | Nonprofit New School of Northern Virginia INC | Education | $5.5M | $10.5M |
| 53 | Global Resilience Exchange INC | Community Improvement & Capacity Building | $5.4M | $2.5M |
| 54 | Gesher School INC | Education | $5.3M | $10.1M |
| 55 | Irrigation Association | Unclassified | $5.3M | $5.2M |
| 56 | Peterson Family Foundation | Community Improvement & Capacity Building | $5.0M | $2.4M |
| 57 | Society of Neurointerventional Surgery | Unclassified | $5.0M | $7.8M |
| 58 | International Action Network | International, Foreign Affairs & National Security | $5.0M | $3.3M |
| 59 | Business Finance Group INC | Unclassified | $4.9M | $8.4M |
| 60 | Fairfax University of America | Education | $4.8M | $17.1M |
| 61 | Fairfax County Park Foundation INC | Community Improvement & Capacity Building | $4.7M | $5.4M |
| 62 | Fairfax County Convention and Visitors Corporation | Community Improvement & Capacity Building | $4.6M | $3.4M |
| 63 | American Society of Nuclear Cardiology | Diseases, Disorders & Medical Disciplines | $4.6M | $9.5M |
| 64 | Co2 Coalition INC | Environment | $4.5M | $3.5M |
| 65 | Lysosomal and Rare Disorders Research and Treatment Center INC | Medical Research | $4.4M | $2.4M |
| 66 | Montclair Property Owners Association INC | Unclassified | $4.4M | $4.2M |
| 67 | American Village Communities INC | Housing & Shelter | $4.3M | $14.7M |
| 68 | Islamic Medical Association of North America INC | Public Safety, Disaster Preparedness & Relief | $4.1M | $7.8M |
| 69 | Insight Memory Care Center | Diseases, Disorders & Medical Disciplines | $4.1M | $4.0M |
| 70 | NRA Civil Rights Defense Fund | Civil Rights, Social Action & Advocacy | $4.0M | $16.7M |
| 71 | Northern Virginia Science Center Foundation | Arts, Culture & Humanities | $3.9M | $15.7M |
| 72 | American Helicopter Society International INC | Unclassified | $3.8M | $2.2M |
| 73 | Allergy and Asthma Network-mothers of Asthmatics INC | Unclassified | $3.8M | $1.7M |
| 74 | Harvey S Lowe Jr and Susan Hitchcock-lowe | Philanthropy, Voluntarism & Grantmaking | $3.6M | $7.2M |
| 75 | George Mason Research Foundation INC | Education | $3.6M | $989K |
| 76 | Service Employees International Union | Unclassified | $3.4M | $267K |
| 77 | Recreation Vehicle Dealers Association of North America | Unclassified | $3.3M | $7.1M |
| 78 | Divine Mercy Care | Health Care | $3.2M | $1.1M |
| 79 | National Utility Contractors Association INC | Community Improvement & Capacity Building | $3.2M | $3.7M |
| 80 | Aats Foundation | Medical Research | $2.9M | $13.0M |
| 81 | Citizens Alliance of America Foundation INC | Community Improvement & Capacity Building | $2.8M | $307K |
| 82 | The Temple Foundation INC | Housing & Shelter | $2.8M | $2.9M |
| 83 | Radioloy Business Management Association | Unclassified | $2.7M | $2.7M |
| 84 | The Arc of Northern Virginia | Unclassified | $2.7M | $2.5M |
| 85 | Professional Pest Management Alliance | Community Improvement & Capacity Building | $2.7M | $2.4M |
| 86 | Claude Moore Opportunities | Youth Development | $2.7M | $1.3M |
| 87 | Britepaths INC | Unclassified | $2.6M | $1.3M |
| 88 | Alpha Omega Clinic and Consultation | Unclassified | $2.5M | $463K |
| 89 | Center for Advancing Public Health | Health Care | $2.5M | $2.2M |
| 90 | Northern Virginia Dental Clinic INC | Health Care | $2.3M | $1.8M |
| 91 | Fairfax Cable Access Corporation | Arts, Culture & Humanities | $2.2M | $13.5M |
| 92 | Harry and Zoe Poole Foundation | Philanthropy, Voluntarism & Grantmaking | $2.1M | $3.2M |
| 93 | Katsucon Entertainment INC | Human Services | $2.1M | $2.0M |
| 94 | Van Metre Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.0M | $5.2M |
| 95 | The George Mason University Instructional Foundation INC | Education | $2.0M | $18.4M |
| 96 | Main Street Child Development Center Incorporated | Human Services | $2.0M | $3.1M |
| 97 | American String Teachers Association Incorporated | Arts, Culture & Humanities | $2.0M | $1.8M |
| 98 | St. Philopateer Coptic Orthodox Church of Vienna Va | Religion-Related | $2.0M | $6.7M |
| 99 | Arts Council of Fairfax County INC | Unclassified | $1.9M | $2.4M |
| 100 | Safe Routes to School National Partnership | Human Services | $1.9M | $1.7M |