| 1 | Kaiser Foundation Health Plan of the Northwest | Health Care | $6.3B | $2.3B |
| 2 | Health Share of Oregon | Health Care | $3.6B | $363.8M |
| 3 | Careoregon INC | Health Care | $2.6B | $1.1B |
| 4 | Legacy Emanuel Hospital & Health Center | Health Care | $1.2B | $454.9M |
| 5 | Oregon Community Foundation | Philanthropy, Voluntarism & Grantmaking | $772.0M | $3.3B |
| 6 | Oregon Dental Service | Unclassified | $664.8M | $365.1M |
| 7 | Onpoint Community Credit Union | Unclassified | $559.2M | $9.7B |
| 8 | Legacy Good Samaritan Hospital and Medical Center Payroll Dept | Health Care | $533.0M | $398.9M |
| 9 | Legacy Health | Health Care | $492.3M | $2.0B |
| 10 | Oregon Teamster Employers Trust | Unclassified | $420.9M | $246.5M |
| 11 | Mercy Corps | International, Foreign Affairs & National Security | $379.3M | $383.3M |
| 12 | Meyer Memorial Trust | Philanthropy, Voluntarism & Grantmaking | $341.3M | $901.2M |
| 13 | Lewis and Clark College | Education | $325.8M | $630.4M |
| 14 | Health Plan of Careoregon INC | Health Care | $318.9M | $138.0M |
| 15 | Reed Institute | Education | $309.3M | $1.1B |
| 16 | Harrison Electrical Workers Trust Fund | Unclassified | $295.6M | $456.9M |
| 17 | Goodwill Industries of the Columbia Willamette | Employment | $283.7M | $467.6M |
| 18 | James F and Marion L Miller Foundation | Philanthropy, Voluntarism & Grantmaking | $279.9M | $178.5M |
| 19 | University of Portland | Education | $274.5M | $718.8M |
| 20 | Ochin INC | Health Care | $273.8M | $194.6M |
| 21 | Energy Trust of Oregon INC | Environment | $251.2M | $96.0M |
| 22 | Eighth District Electrical Benefit | Unclassified | $244.6M | $148.0M |
| 23 | Silver Family Foundation | Philanthropy, Voluntarism & Grantmaking | $236.0M | $145.2M |
| 24 | Lemelson Foundation | Philanthropy, Voluntarism & Grantmaking | $228.0M | $414.4M |
| 25 | Oregon Health and Science University Foundation | Education | $175.5M | $1.6B |
| 26 | Central City Concern INC | Mental Health & Crisis Intervention | $164.2M | $277.9M |
| 27 | Collins Foundation | Unclassified | $134.5M | $234.9M |
| 28 | Oregon Food Bank INC | Unclassified | $133.7M | $99.1M |
| 29 | Terwilliger Plaza INC | Human Services | $112.9M | $268.2M |
| 30 | Vocational Development Foundation | Employment | $111.3M | $327.8M |
| 31 | Cascadia Health | Mental Health & Crisis Intervention | $103.7M | $107.8M |
| 32 | Oregon Public Broadcasting | Arts, Culture & Humanities | $95.1M | $154.1M |
| 33 | Alaska Teamster-employer Welfare Trust | Unclassified | $94.7M | $39.6M |
| 34 | Unitus Community Credit Union | Unclassified | $91.7M | $1.7B |
| 35 | Ride Connection INC | Human Services | $80.2M | $39.8M |
| 36 | Oregon Laborers-employers Health and Welfare Trust Fund | Unclassified | $79.8M | $62.1M |
| 37 | Sheet Metal Workers 16 Health and Welfare Fund | Unclassified | $78.3M | $43.4M |
| 38 | Hollis Foundation | Philanthropy, Voluntarism & Grantmaking | $71.3M | $147.5M |
| 39 | Trillium Family Services INC | Housing & Shelter | $71.2M | $50.8M |
| 40 | Cambia Health Foundation | Philanthropy, Voluntarism & Grantmaking | $67.6M | $100.6M |
| 41 | Relay Resources | Employment | $62.3M | $72.3M |
| 42 | Providence St. Vincent Medical Foundation | Health Care | $61.7M | $359.3M |
| 43 | The Immigrant and Refugee Community Organization | Unclassified | $60.4M | $23.6M |
| 44 | Multnomah Athletic Club | Unclassified | $59.7M | $116.6M |
| 45 | The Native American Rehabilitation Assoc of the Northwest INC | Mental Health & Crisis Intervention | $59.5M | $61.7M |
| 46 | Craft3 | Community Improvement & Capacity Building | $58.3M | $236.7M |
| 47 | Oregon Homecare Workers Supplemental Tr | Health Care | $58.1M | $50.1M |
| 48 | Vital Projects Fund INC | Unclassified | $57.2M | $362.9M |
| 49 | Oregon Essential Workforce Health Care Fund | Mutual & Membership Benefit | $57.0M | $102.3M |
| 50 | Lifeworks Nw | Mental Health & Crisis Intervention | $53.7M | $111.9M |
| 51 | Bonneville Environmental Foundation | Environment | $51.8M | $68.8M |
| 52 | Catlin Gabel School | Education | $51.2M | $99.6M |
| 53 | Portland State University Foundation | Unclassified | $49.4M | $195.7M |
| 54 | Familycare INC | Health Care | $45.1M | $109.4M |
| 55 | Albertina Kerr Centers | Human Services | $44.6M | $61.8M |
| 56 | Neighborhood Health Center | Health Care | $43.1M | $38.4M |
| 57 | Western Rivers Conservancy | Environment | $42.1M | $78.5M |
| 58 | Transition Projects INC | Unclassified | $42.0M | $17.3M |
| 59 | Oregon Humane Society | Animal-Related | $41.3M | $112.8M |
| 60 | International Brotherhood of Electrical Workers | Unclassified | $41.2M | $64.8M |
| 61 | Morrison Child & Family Services | Health Care | $41.2M | $29.7M |
| 62 | Northwest Energy Efficiency Alliance INC | Environment | $41.1M | $20.7M |
| 63 | Willamette View Manor INC | Human Services | $39.8M | $163.5M |
| 64 | Portland Art Museum | Arts, Culture & Humanities | $39.2M | $235.6M |
| 65 | Northwest Portland Area Indian Health Board | Health Care | $38.9M | $17.5M |
| 66 | Elks Youth Eye Service | Mutual & Membership Benefit | $38.6M | $62.0M |
| 67 | Planned Parenthood of the Columbia Willamette INC | Health Care | $38.1M | $64.6M |
| 68 | Providence Portland Medical Foundation | Health Care | $38.0M | $249.3M |
| 69 | Sheet Metal Workers 100 Welfare Fund | Unclassified | $37.6M | $68.1M |
| 70 | United Way of the Columbia- Willamette | Philanthropy, Voluntarism & Grantmaking | $37.4M | $41.7M |
| 71 | Reach Community Development INC | Housing & Shelter | $36.2M | $120.0M |
| 72 | Dove Lewis Emergency Animal Hospital INC | Animal-Related | $36.1M | $26.1M |
| 73 | Oregon Homecare Workers Benefit Tr | Mutual & Membership Benefit | $36.0M | $24.0M |
| 74 | Robison Jewish Home | Human Services | $35.3M | $43.9M |
| 75 | Chiles Foundation | Unclassified | $35.1M | $9.3M |
| 76 | Plumbing & Pipefitting Industry Health & Welfare Fund Local Union | Unclassified | $34.9M | $44.5M |
| 77 | Habitat for Humanity Portland Metro East | Housing & Shelter | $34.0M | $59.7M |
| 78 | Travel Portland | Unclassified | $33.7M | $20.6M |
| 79 | Metropolitan Public Defender Service INC | Unclassified | $33.5M | $30.0M |
| 80 | Self Enhancement INC | Unclassified | $33.4M | $48.4M |
| 81 | Warner Pacific University | Education | $33.0M | $26.1M |
| 82 | Oregon Museum of Science and Industry | Arts, Culture & Humanities | $32.8M | $68.2M |
| 83 | Stand for Children Leadership Center | Youth Development | $32.5M | $50.4M |
| 84 | Worksystems INC | Employment | $32.2M | $11.4M |
| 85 | Albina Vision INC | Community Improvement & Capacity Building | $31.9M | $37.7M |
| 86 | IBEW No 271-NECA Health and Benefit Fund | Mutual & Membership Benefit | $31.8M | $22.2M |
| 87 | Coda INC | Mental Health & Crisis Intervention | $31.5M | $40.3M |
| 88 | Seeding Justice | Philanthropy, Voluntarism & Grantmaking | $31.5M | $31.0M |
| 89 | Bibleproject | Religion-Related | $31.2M | $34.6M |
| 90 | Oregon Education Association | Employment | $31.0M | $62.8M |
| 91 | Western States Local Union Trust Fund of the Office Employees Inter | Unclassified | $30.7M | $17.9M |
| 92 | Albina Head Start INC | Unclassified | $30.6M | $50.9M |
| 93 | Cascade Aids Project | Diseases, Disorders & Medical Disciplines | $30.2M | $19.5M |
| 94 | Rose Villa INC | Human Services | $29.6M | $164.8M |
| 95 | Latino Network | Human Services | $29.2M | $29.6M |
| 96 | United Metal Trades Association Trust | Unclassified | $29.0M | $39.9M |
| 97 | Oregon Symphony Association | Arts, Culture & Humanities | $28.8M | $31.8M |
| 98 | Nelson Trust | Mutual & Membership Benefit | $27.4M | $37.7M |
| 99 | Human Solutions INC | Community Improvement & Capacity Building | $27.4M | $53.4M |
| 100 | Volunteers of America INC | Unclassified | $27.3M | $28.5M |