| 1 | Asante | Health Care | $1.6B | $2.2B |
| 2 | Rogue Valley Manor | Human Services | $65.6M | $237.9M |
| 3 | La Clinica Del Valle Family Health Care Center INC | Unclassified | $61.5M | $72.4M |
| 4 | Columbiacare Services INC | Mental Health & Crisis Intervention | $60.8M | $82.8M |
| 5 | Asante Physician Partners | Health Care | $60.8M | $19.4M |
| 6 | Southern Oregon Goodwill Industries | Employment | $48.8M | $34.3M |
| 7 | Access | Unclassified | $45.0M | $18.1M |
| 8 | Rogue Community Health | Health Care | $42.6M | $28.6M |
| 9 | University Retirement Community at Davis INC | Human Services | $39.3M | $120.3M |
| 10 | Mercy Flights INC | Health Care | $36.2M | $34.4M |
| 11 | Mira Bella | Housing & Shelter | $34.7M | $168.3M |
| 12 | Mirabella at South Waterfront | Housing & Shelter | $31.2M | $159.3M |
| 13 | Holladay Park Plaza INC | Human Services | $26.5M | $79.2M |
| 14 | Pacific Retirement Services INC | Human Services | $26.3M | $72.4M |
| 15 | St. Marys of Medford INC | Unclassified | $19.5M | $33.1M |
| 16 | On Track | Unclassified | $18.6M | $36.2M |
| 17 | Addictions Recovery Center INC | Mental Health & Crisis Intervention | $18.0M | $16.8M |
| 18 | Logos Charter School | Unclassified | $16.6M | $27.0M |
| 19 | Pathway Enterprises INC | Human Services | $16.4M | $15.1M |
| 20 | Kids Unlimited of Oregon | Youth Development | $14.1M | $21.7M |
| 21 | Cascade Manor INC | Human Services | $13.3M | $39.5M |
| 22 | Carrico Family Foundation | Philanthropy, Voluntarism & Grantmaking | $10.9M | $30.3M |
| 23 | Grace Cascade Christian Schools | Unclassified | $10.0M | $44.6M |
| 24 | Living Opportunities INC | Employment | $9.7M | $8.6M |
| 25 | Rogue Retreat | Mental Health & Crisis Intervention | $9.5M | $12.2M |
| 26 | Oregon Center for Creative Learning | Arts, Culture & Humanities | $9.1M | $20.4M |
| 27 | Peter Britt Gardens Music and Arts Festival Association | Unclassified | $8.4M | $12.3M |
| 28 | Vibes Public Charter School | Education | $6.9M | $2.8M |
| 29 | The Family Nurturing Center | Education | $6.7M | $6.1M |
| 30 | Southern Oregon Public Defender INC | Crime & Legal-Related | $6.2M | $5.1M |
| 31 | Rogue Workforce Partnership | Employment | $5.6M | $2.7M |
| 32 | Arthur R Dubs Foundation | Philanthropy, Voluntarism & Grantmaking | $5.4M | $20.4M |
| 33 | Asante Foundation | Health Care | $5.0M | $68.6M |
| 34 | Oasis Center of the Rogue Valley | Human Services | $4.6M | $3.5M |
| 35 | Community Works INC | Mental Health & Crisis Intervention | $4.6M | $5.0M |
| 36 | Hearts with a Mission | Human Services | $4.2M | $5.2M |
| 37 | Southern Oregon Friends of Hospice | Human Services | $4.0M | $5.8M |
| 38 | Creative Supports INC | Human Services | $3.9M | $6.0M |
| 39 | Society of St. Vincent de Paul | Unclassified | $3.7M | $5.9M |
| 40 | Maslow Project | Youth Development | $3.6M | $6.6M |
| 41 | Reliance Ehealth Collaborative | Health Care | $3.5M | $1.2M |
| 42 | Young Mens Christian Association | Human Services | $3.5M | $4.6M |
| 43 | Habitat for Humanity International INC | Housing & Shelter | $3.5M | $6.9M |
| 44 | The Arc Jackson County | Human Services | $3.2M | $2.3M |
| 45 | Providence Community Health Foundation | Unclassified | $3.2M | $16.0M |
| 46 | Youth 71FIVE Ministries | Youth Development | $3.1M | $8.7M |
| 47 | Oregon Hunters Association | Unclassified | $2.8M | $1.9M |
| 48 | Southern Oregon Public Television INC | Arts, Culture & Humanities | $2.8M | $3.2M |
| 49 | Thedove Media INC | Philanthropy, Voluntarism & Grantmaking | $2.7M | $1.8M |
| 50 | Blum Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.6M | $6.2M |
| 51 | Chamber of Medford Jackson County | Unclassified | $2.5M | $1.1M |
| 52 | Gordon Elwood Foundation | Philanthropy, Voluntarism & Grantmaking | $2.3M | $10.6M |
| 53 | United Way of Jackson County INC | Philanthropy, Voluntarism & Grantmaking | $2.1M | $2.5M |
| 54 | Nazarene Hospital Foundation | Health Care | $2.1M | $426K |
| 55 | Craterian Performances Company | Arts, Culture & Humanities | $2.1M | $5.8M |
| 56 | Southern Oregon Humane Society | Animal-Related | $2.0M | $11.6M |
| 57 | Upper Klamath Basin Ag Collaborative | Environment | $1.9M | $740K |
| 58 | USA Dance INC | Arts, Culture & Humanities | $1.9M | $2.3M |
| 59 | Jackson County Child Abuse Task Force | Unclassified | $1.9M | $2.8M |
| 60 | Rogue Valley Manor Memorial Foundation | Human Services | $1.9M | $22.2M |
| 61 | Center for Non Profit Legal Services | Unclassified | $1.7M | $2.0M |
| 62 | Carpenter Foundation | Unclassified | $1.7M | $18.6M |
| 63 | Coalicion Fortaleza | Public Safety, Disaster Preparedness & Relief | $1.5M | $1.8M |
| 64 | Oregon Hunters Association | Recreation & Sports | $1.4M | $1.7M |
| 65 | Natives of One Wind Indigenous Alliance | Human Services | $1.4M | $2.6M |
| 66 | Casa of Jackson County INC | Civil Rights, Social Action & Advocacy | $1.3M | $1.8M |
| 67 | Valley School of Southern Oregon | Education | $1.3M | $1.9M |
| 68 | Pacific Bible College | Education | $1.3M | $2.2M |
| 69 | Stabbin Wagon | Unclassified | $1.2M | $556K |
| 70 | Understory Initiative | Environment | $1.2M | $282K |
| 71 | Rogue Valley Mentoring | Youth Development | $1.1M | $664K |
| 72 | Rogue Valley Soccer Club | Unclassified | $1.0M | $212K |
| 73 | Reclaiming Lives | Unclassified | $916K | $157K |
| 74 | Anna May Family Foundation | Philanthropy, Voluntarism & Grantmaking | $888K | $2.9M |
| 75 | Merlin & Jo Ann Fjarli Foundation INC | Philanthropy, Voluntarism & Grantmaking | $875K | $7.6M |
| 76 | Dreamz Work | Human Services | $875K | $829K |
| 77 | Consumer Credit Counseling Service of Southern Oregon INC | Human Services | $793K | $1.5M |
| 78 | Association of Insolvency & Restructuring Advisors | Unclassified | $783K | $462K |
| 79 | Southern Oregon Regional Economic Development INC | Unclassified | $752K | $6.1M |
| 80 | Fraternal Order of Eagles | Mutual & Membership Benefit | $729K | $1.1M |
| 81 | Southern Oregon Historical Society | Arts, Culture & Humanities | $702K | $1.3M |
| 82 | Community Volunteer Network | Human Services | $688K | $267K |
| 83 | Rvm Lively Oak Housing Corporation | Housing & Shelter | $685K | $1.7M |
| 84 | Rvm Davis Housing Corporation | Housing & Shelter | $681K | $3.0M |
| 85 | Jackson County Community Services Consortium INC | Unclassified | $633K | $480K |
| 86 | The Pregnancy Center | Human Services | $628K | $252K |
| 87 | Rvm Ashland Housing Corporation | Housing & Shelter | $625K | $858K |
| 88 | Hillah Shriners | Unclassified | $619K | $2.2M |
| 89 | Set Free Services | Human Services | $588K | $534K |
| 90 | Rvm Eugene Housing Corp. | Housing & Shelter | $586K | $2.1M |
| 91 | Compass House INC | Human Services | $585K | $1.8M |
| 92 | California Chapter of the Foundatn for North American Wild Sheep | Animal-Related | $582K | $1.4M |
| 93 | Gambee Family Foundation | Philanthropy, Voluntarism & Grantmaking | $569K | $17.5M |
| 94 | Rvm Housing Corporation | Housing & Shelter | $569K | $962K |
| 95 | Joe and Frances Naumes Family Foundation INC | Unclassified | $564K | $2.6M |
| 96 | Helping Hands International INC | Human Services | $532K | $282K |
| 97 | Home Builders Assn of Jackson Co INC | Unclassified | $512K | $185K |
| 98 | Resolve Center for Dispute Resolution and Restorative Justice | Crime & Legal-Related | $512K | $536K |
| 99 | Rvm Mansfield Housing Corporation | Housing & Shelter | $510K | $3.1M |
| 100 | Wilderness Trails INC | Human Services | $496K | $1.5M |