| 1 | Knight Foundation | Philanthropy, Voluntarism & Grantmaking | $520.0M | $4.5B |
| 2 | City Fund | Philanthropy, Voluntarism & Grantmaking | $118.6M | $118.7M |
| 3 | Campaign for Great Public Schools | Education | $74.4M | $4.2M |
| 4 | Lemnis | Education | $45.1M | $947.7M |
| 5 | Durban Family Foundation | Philanthropy, Voluntarism & Grantmaking | $39.2M | $57.1M |
| 6 | Luis Palau Association | Religion-Related | $30.6M | $16.7M |
| 7 | Nike Foundation | Philanthropy, Voluntarism & Grantmaking | $30.3M | $47.5M |
| 8 | Sisters of St. Mary of Oregon Maryville Corporation | Health Care | $29.8M | $22.1M |
| 9 | National Network of Abortion Funds | Environment | $29.2M | $65.4M |
| 10 | Vibrant Village Foundation | Philanthropy, Voluntarism & Grantmaking | $26.6M | $100.3M |
| 11 | Community Access Services II INC | Human Services | $25.4M | $13.6M |
| 12 | Oregon Insurance Guaranty Association | Unclassified | $23.9M | $68.9M |
| 13 | The Delaski Family Foundation | Philanthropy, Voluntarism & Grantmaking | $22.4M | $49.4M |
| 14 | St. Marys Home | Human Services | $17.9M | $31.3M |
| 15 | Reser Family Foundation | Philanthropy, Voluntarism & Grantmaking | $17.1M | $84.8M |
| 16 | W Haywood Burns Institute | Youth Development | $16.0M | $13.5M |
| 17 | Family Justice Center of Washington County | Crime & Legal-Related | $14.2M | $15.2M |
| 18 | Edwards Center INC | Employment | $14.0M | $24.4M |
| 19 | Boy Scouts of America | Youth Development | $10.6M | $43.3M |
| 20 | Fido Alliance INC | Community Improvement & Capacity Building | $8.6M | $4.2M |
| 21 | Usta-pacific Northwest Section | Unclassified | $8.2M | $12.1M |
| 22 | Moveon Org Civic Action | Education | $7.8M | $7.1M |
| 23 | Specialized Housing Incorporated | Housing & Shelter | $7.7M | $26.8M |
| 24 | German-american School of Portland | Education | $7.5M | $16.8M |
| 25 | Beaverton Arts Foundation INC | Arts, Culture & Humanities | $7.4M | $9.0M |
| 26 | Oregon Society of Certified Public Accountants | Unclassified | $7.1M | $4.4M |
| 27 | Pci Sig | Community Improvement & Capacity Building | $7.0M | $6.0M |
| 28 | Resource Media a Nonprofit Corporation | Environment | $6.2M | $3.2M |
| 29 | Aim High Pdx | Youth Development | $5.8M | $2.3M |
| 30 | Usb Implementers Forum INC | Community Improvement & Capacity Building | $5.6M | $6.1M |
| 31 | Hope Chinese Charter School | Education | $5.4M | $7.2M |
| 32 | Arco Iris Spanish Immersion Charter School | Education | $5.3M | $14.6M |
| 33 | City View Charter School | Education | $4.9M | $21.6M |
| 34 | Special Olympics Oregon INC | Unclassified | $4.8M | $5.9M |
| 35 | Rmf Foundation | Philanthropy, Voluntarism & Grantmaking | $4.8M | $36.9M |
| 36 | Self-determination Resources INC | Human Services | $4.8M | $3.4M |
| 37 | Washington County Visitors Association | Unclassified | $4.6M | $8.4M |
| 38 | The Walker Family Foundation | Philanthropy, Voluntarism & Grantmaking | $4.4M | $10.7M |
| 39 | Python Software Foundation | Science & Technology | $4.1M | $4.3M |
| 40 | Oregon Youth Soccer Association | Unclassified | $3.9M | $2.4M |
| 41 | The Khronos Group INC | Community Improvement & Capacity Building | $3.9M | $5.7M |
| 42 | La Paz Global | Education | $3.8M | $1.5M |
| 43 | Pacific Ocean Energy Trust | Environment | $3.7M | $1.0M |
| 44 | Valor Global Foundation | Education | $3.2M | $651K |
| 45 | Tournament Golf Foundation INC | Unclassified | $3.0M | $758K |
| 46 | Oregon Gymnastics Academy | Recreation & Sports | $3.0M | $3.1M |
| 47 | Hdmi Forum INC | Community Improvement & Capacity Building | $2.8M | $7.7M |
| 48 | St. Stephens Academy | Education | $2.8M | $1.1M |
| 49 | Hollywood Professional Association INC | Unclassified | $2.7M | $2.2M |
| 50 | Afghan Support Network | Human Services | $2.7M | $503K |
| 51 | Homeplate Youth Services | Human Services | $2.5M | $3.7M |
| 52 | Westside Metros Soccer Club | Recreation & Sports | $2.4M | $1.2M |
| 53 | Compassion First | International, Foreign Affairs & National Security | $2.3M | $1.0M |
| 54 | Renewal House Nw | Mental Health & Crisis Intervention | $2.3M | $1.1M |
| 55 | Palau Foundation for World Evangelism | Unclassified | $2.2M | $2.5M |
| 56 | Z-wave Alliance INC | Unclassified | $2.0M | $2.2M |
| 57 | Infrastructure Masons INC | Community Improvement & Capacity Building | $2.0M | $790K |
| 58 | Roots of Progress | Human Services | $1.9M | $1.2M |
| 59 | The Islamic Society of Greater Portland | Unclassified | $1.9M | $2.5M |
| 60 | Good Samaritan Ministries | Human Services | $1.8M | $1.7M |
| 61 | Climate Foundation | Science & Technology | $1.7M | $2.7M |
| 62 | Raices de Bienestar | Mental Health & Crisis Intervention | $1.7M | $1.2M |
| 63 | Donors of Color Network INC | Philanthropy, Voluntarism & Grantmaking | $1.7M | $3.4M |
| 64 | International Technology Law Association INC | Unclassified | $1.6M | $1.2M |
| 65 | Assistance League of Greater Portland | Human Services | $1.6M | $6.0M |
| 66 | Compute Express Link Consortium INC | Community Improvement & Capacity Building | $1.6M | $3.6M |
| 67 | Universal Chiplet Interconnect Express INC | Science & Technology | $1.5M | $4.2M |
| 68 | Usvba Columbia Empire Region Volleyball Association | Unclassified | $1.5M | $1.1M |
| 69 | Family Promise of Greater Washington County | Human Services | $1.4M | $1.8M |
| 70 | Trusted Computing Group | Community Improvement & Capacity Building | $1.4M | $3.1M |
| 71 | Forward Stride | Human Services | $1.4M | $3.4M |
| 72 | Institute for Learning Innovation | Education | $1.3M | $519K |
| 73 | Tualatin Hills Swim Club | Unclassified | $1.3M | $606K |
| 74 | Portland Basketball Officials Association | Recreation & Sports | $1.2M | $85K |
| 75 | Plumbing and Piping Industry Council INC | Unclassified | $1.2M | $3.6M |
| 76 | H E Anderson Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $6.1M |
| 77 | Shokookai of Portland | Arts, Culture & Humanities | $1.2M | $688K |
| 78 | Housing Independence INC | Human Services | $1.2M | $272K |
| 79 | Public Safety Chaplaincy INC | Unclassified | $1.1M | $556K |
| 80 | United States Postgresql Association | Community Improvement & Capacity Building | $1.1M | $1.2M |
| 81 | Neuromatch Academy INC | Education | $1.1M | $739K |
| 82 | Ongo Alliance | Community Improvement & Capacity Building | $1.1M | $1.2M |
| 83 | Parkinsons Resources of Oregon | Unclassified | $1.1M | $3.8M |
| 84 | Mike Silva Evangelism International INC | Unclassified | $1.0M | $504K |
| 85 | The Ethernet Alliance | Community Improvement & Capacity Building | $1.0M | $331K |
| 86 | Northwest Pbis Network INC | Education | $1.0M | $1.1M |
| 87 | Michael Zeff Fund | Human Services | $998K | $2.4M |
| 88 | Village Home Education Resource Center | Education | $957K | $544K |
| 89 | Wi-sun Alliance INC | Community Improvement & Capacity Building | $896K | $709K |
| 90 | Association for the Study of Higher Education | Education | $888K | $1.2M |
| 91 | Griffin Center | Human Services | $827K | $850K |
| 92 | Ukrainian Foundation | Human Services | $823K | $81K |
| 93 | Alliance for Equity in Montessori Education | Education | $810K | $247K |
| 94 | Candlelighters for Children with Cancer | Unclassified | $766K | $667K |
| 95 | Ray of Hope INC | International, Foreign Affairs & National Security | $764K | $705 |
| 96 | Imagine Black | Civil Rights, Social Action & Advocacy | $747K | $728K |
| 97 | Beaverton Area Chamber of Commerce | Unclassified | $738K | $285K |
| 98 | Gaas Mantech INC | Unclassified | $736K | $808K |
| 99 | Operation One | International, Foreign Affairs & National Security | $726K | $274K |
| 100 | Subcutaneous Drug Development & Delivery Consortium INC | Community Improvement & Capacity Building | $722K | $1.2M |