| 1 | Cancer Centers of Southwest Oklahoma LLC | Health Care | $48.3M | $43.7M |
| 2 | McMahon Foundation | Unclassified | $23.6M | $49.4M |
| 3 | Goodwill Industries of Southwest Oklahoma & North Texas INC | Employment | $9.0M | $10.9M |
| 4 | Marie Detty Youth & Family Service Center INC | Human Services | $7.5M | $6.9M |
| 5 | Cameron University Foundation INC | Education | $6.8M | $37.6M |
| 6 | Q U E S T Ministries of Oklahoma INC | Religion-Related | $3.7M | $3.1M |
| 7 | Lawton Food Bank INC | Unclassified | $3.5M | $2.2M |
| 8 | Lawton Chamber of Commerce | Unclassified | $1.7M | $2.8M |
| 9 | Young Mens Christian Association of Lawton Oklahoma | Human Services | $1.6M | $4.4M |
| 10 | Breast Center | Unclassified | $1.6M | $1.7M |
| 11 | United Way of Southwest Oklahoma INC | Philanthropy, Voluntarism & Grantmaking | $1.3M | $2.5M |
| 12 | Lawton Enhancement Trust Authority | Community Improvement & Capacity Building | $1.2M | $478K |
| 13 | Wichita Mountains Prevention Network INC | Human Services | $1.2M | $462K |
| 14 | Quality Enterprises of Lawton INC | Human Services | $1.1M | $419K |
| 15 | Lawton Public School Foundation INC | Unclassified | $1.1M | $3.0M |
| 16 | Museum of the Great Plains Authority | Arts, Culture & Humanities | $1.0M | $7.8M |
| 17 | Lawton-fort Sill Economic Development Corporation | Unclassified | $942K | $1.9M |
| 18 | Christian Family Counseling Center INC | Human Services | $935K | $657K |
| 19 | Lawton Korean War Veterans Association | Public & Societal Benefit | $865K | $77K |
| 20 | Y I E L D INC | Education | $708K | $489K |
| 21 | Comanche County Memorial Hospital Foundation INC | Unclassified | $619K | $4.5M |
| 22 | Center for Creative Living Corporat | Unclassified | $599K | $374K |
| 23 | Historical Association of the Lawton Rangers INC | Arts, Culture & Humanities | $551K | $564K |
| 24 | Goodyear Recreation Associaton of Lawton Oklahoma INC | Unclassified | $534K | $558K |
| 25 | Comanche County Saddle & Sirloin Club INC | Youth Development | $520K | $132K |
| 26 | Holiday in the Park | Recreation & Sports | $505K | $641K |
| 27 | Southwest Educational Ministries Association | Unclassified | $505K | $2.1M |
| 28 | Teen Court Incorporated | Crime & Legal-Related | $503K | $380K |
| 29 | Fista Foundation | Community Improvement & Capacity Building | $461K | $471K |
| 30 | The National Organization to End Pet Overpopulation INC | Unclassified | $453K | $39K |
| 31 | Tribal Leadership Council INC | Youth Development | $450K | $92K |
| 32 | Great Plains Vo-tech Foundation INC | Unclassified | $442K | $2.6M |
| 33 | Southwest Oklahoma Intertribal Health Board INC | Health Care | $434K | $15K |
| 34 | McMahon Auditorium Authority | Arts, Culture & Humanities | $415K | $1.1M |
| 35 | Pregnancy Resource Center of Sw Oklahoma INC | Health Care | $413K | $1.2M |
| 36 | Family Promise of Lawton Incorporated | Human Services | $392K | $271K |
| 37 | Lawton Evening Optimist Soccer Association | Unclassified | $377K | $659K |
| 38 | Astronomical League | Science & Technology | $370K | $1.3M |
| 39 | Katta Ayirala Foundation | Health Care | $335K | $1.0M |
| 40 | Lawton Philharmonic Society INC | Unclassified | $326K | $127K |
| 41 | Spread the Word Ministries Worship Center INC | Religion-Related | $317K | $1.3M |
| 42 | Hearts That Care Volunteer Health Clinic INC | Health Care | $314K | $1.6M |
| 43 | Stanley Bruce Davis Foundation INC | Philanthropy, Voluntarism & Grantmaking | $302K | $535K |
| 44 | Arts for All INC | Arts, Culture & Humanities | $283K | $166K |
| 45 | Lawton Support Services Corporation | Housing & Shelter | $282K | $1.2M |
| 46 | International Association of Fire Fighters | Unclassified | $272K | $168K |
| 47 | Friends of the Lawton Public Library | Unclassified | $249K | $273K |
| 48 | Lawton Heritage Association INC | Unclassified | $240K | $959K |
| 49 | Oklahoma Farm Bureau | Unclassified | $204K | $1.0M |
| 50 | Lawton Community Theatre INC | Arts, Culture & Humanities | $183K | $261K |
| 51 | Message of Life Ministries | International, Foreign Affairs & National Security | $180K | $217K |
| 52 | Casa of Southwest Oklahoma INC | Crime & Legal-Related | $178K | $241K |
| 53 | Camp Lu-jo Kismif INC | Philanthropy, Voluntarism & Grantmaking | $172K | $883K |
| 54 | Lovesick Ministries | Religion-Related | $170K | $458K |
| 55 | Ancient Free & Accepted Masons of Oklahoma | Unclassified | $159K | $326K |
| 56 | Old Towne Square INC | Housing & Shelter | $155K | $2.5M |
| 57 | Laura Fields Trust | Unclassified | $145K | $2.2M |
| 58 | Coxs Store Volunteer Fire Department INC | Public Safety, Disaster Preparedness & Relief | $139K | $119K |
| 59 | Leslie Powell Foundation INC | Unclassified | $138K | $1.3M |
| 60 | Embrace Hope Collaboratorium INC | Human Services | $125K | $77K |
| 61 | Southwestern Oklahoma Recreation and Tourist Association INC | Unclassified | $120K | $18K |
| 62 | Lawton Farmes Market Institute | Food, Agriculture & Nutrition | $109K | $2.8M |
| 63 | Lawton Mobile Meals INC | Unclassified | $109K | $94K |
| 64 | National Ambucs INC | Unclassified | $103K | $76K |
| 65 | Comanche Language and Culture Preservation Committee | Arts, Culture & Humanities | $101K | $1K |
| 66 | Great Plains American Business Club Ambucs Charity Fund | Unclassified | $93K | $79K |
| 67 | Grandeur of Grace Incorporated | Public & Societal Benefit | $92K | $39K |
| 68 | Habitat for Humanity International INC | Unclassified | $91K | $736K |
| 69 | Flower Mound Parent Teacher Organization INC | Education | $88K | $83K |
| 70 | Communication Workers of America | Unclassified | $86K | $183K |
| 71 | Humane Society of Lawton Comanche County | Unclassified | $86K | $118K |
| 72 | Hungry Hearts Feeding Ministry INC | Religion-Related | $85K | $49K |
| 73 | Vision of Hope INC | Unclassified | $79K | $460K |
| 74 | All About Understanding | Education | $77K | $53K |
| 75 | Veterans of Foreign Wars of the United States Dept of Oklahoma | Unclassified | $74K | $409K |
| 76 | Pecan Creek Volunteer Fire Department INC | Public Safety, Disaster Preparedness & Relief | $71K | $217K |
| 77 | Crime Stoppers of Lawton INC | Crime & Legal-Related | $67K | $662K |
| 78 | National Association of Letter Carriers | Unclassified | $65K | $7K |
| 79 | Lawton Rotary Leadership Institute | Education | $64K | $301K |
| 80 | Enclave Owners Association INC | Housing & Shelter | $55K | $132K |
| 81 | Southwest Oklahoma Home Builders Association INC | Unclassified | $48K | $149K |
| 82 | First United Methodist Foundation of Lawton Oklahoma | Religion-Related | $47K | $348K |
| 83 | Lawton Fort Sill Fires Patriots INC | Community Improvement & Capacity Building | $45K | $69K |
| 84 | M28 Ministries INC | International, Foreign Affairs & National Security | $40K | $173K |
| 85 | Summit One INC | Housing & Shelter | $37K | $374K |
| 86 | Church of Blood of Christ | Religion-Related | $37K | $1 |
| 87 | Fulbright-helvey Foundation | Philanthropy, Voluntarism & Grantmaking | $36K | $544K |
| 88 | Southwestern Clinic Hospital Auxiliary INC | Health Care | $32K | $194K |
| 89 | Wichita Mountains Estates Fire | Public Safety, Disaster Preparedness & Relief | $29K | $95K |
| 90 | Scilfast INC | Community Improvement & Capacity Building | $18K | $1 |
| 91 | Impressions Academy of Beauty INC | Education | $17K | $48K |
| 92 | Bigger Than Music INC | Religion-Related | $4K | $2K |
| 93 | Friends of the Museum of the Great Plains INC | Arts, Culture & Humanities | $215 | $79K |
| 94 | Barkingwater Productions INC | Arts, Culture & Humanities | $150 | $1 |
| 95 | Helen W Holliday Foundation INC | Philanthropy, Voluntarism & Grantmaking | $16 | $16K |
| 96 | Great Plains Chapter-shrm | Community Improvement & Capacity Building | $0 | $0 |
| 97 | Lawton-fort Sill Bridge Club | Community Improvement & Capacity Building | $0 | $0 |
| 98 | PTA Oklahoma Congress | Unclassified | $0 | $0 |
| 99 | Lawton Heat Volleyball Club | Recreation & Sports | $0 | $0 |
| 100 | Lawton Pro Musica INC | Arts, Culture & Humanities | $0 | $0 |