| 1 | Knapp-swezey Foundation INC | Unclassified | $109.7M | $17.9M |
| 2 | Brookhaven Health Care Services Corporation | Health Care | $46.9M | $37.6M |
| 3 | Economic Opportunity Council of Suffolk INC | Community Improvement & Capacity Building | $33.8M | $16.3M |
| 4 | L I Child and Family Development Services INC | Unclassified | $27.6M | $10.3M |
| 5 | Sepa Mujer INC | Unclassified | $5.3M | $2.8M |
| 6 | Patchogue Village Center for the Performing Arts INC | Arts, Culture & Humanities | $4.0M | $1.8M |
| 7 | Patchogue F D Ambulance Company INC | Health Care | $2.9M | $5.2M |
| 8 | Mercy Center Ministries INC | Human Services | $2.8M | $2.7M |
| 9 | American Federation of Teachers | Unclassified | $1.1M | $1.2M |
| 10 | International Brotherhood of Electrical Workers | Unclassified | $1.0M | $2.2M |
| 11 | Frances and Peter Robotti Foundation | Philanthropy, Voluntarism & Grantmaking | $891K | $2.6M |
| 12 | Angels of Long Island INC | Unclassified | $660K | $342K |
| 13 | Patchogue Arts Council INC | Arts, Culture & Humanities | $606K | $245K |
| 14 | Utility Workers Union of America Afl-cio | Unclassified | $458K | $1.1M |
| 15 | American Federation of Teachers | Unclassified | $376K | $193K |
| 16 | Patchogue-medford Youth Services | Human Services | $373K | $317K |
| 17 | Plaza Mac INC | Arts, Culture & Humanities | $326K | $143K |
| 18 | Patchogue Community Service Foundation INC | Philanthropy, Voluntarism & Grantmaking | $320K | $57K |
| 19 | North Patchogue Volunteer Exempt | Philanthropy, Voluntarism & Grantmaking | $257K | $1.7M |
| 20 | Codanceco INC | Unclassified | $216K | $114K |
| 21 | North Patchogue Fire Department INC | Public Safety, Disaster Preparedness & Relief | $170K | $312K |
| 22 | Patchogue-medford Youth Soccer League INC | Recreation & Sports | $164K | $121K |
| 23 | Ministerio Redes INC | Religion-Related | $163K | $8K |
| 24 | Suffolk County School Superintendents Association | Community Improvement & Capacity Building | $156K | $75K |
| 25 | Kiwanis Club of Patch Charitable Foundation | Unclassified | $153K | $63K |
| 26 | Suffolk Intergroup Association of Alcoholics Anonymous | Unclassified | $140K | $132K |
| 27 | Davis Park Fire Department INC | Public Safety, Disaster Preparedness & Relief | $125K | $99K |
| 28 | Greater Patchogue Foundation INC | Arts, Culture & Humanities | $123K | $121K |
| 29 | Little League Baseball INC | Unclassified | $120K | $84K |
| 30 | Iglesia Cristianna Restaurando Almas Para Cristo INC | Religion-Related | $110K | $247K |
| 31 | Greater Patchogue Chamber of Commerce INC | Community Improvement & Capacity Building | $103K | $80K |
| 32 | Iglesia Pentecostal Roca de Salvacion de Patchogue INC | Religion-Related | $98K | $1 |
| 33 | Benevolent & Protective Order of Elks of the USA | Unclassified | $96K | $517K |
| 34 | Meals on Wheels of Greater Poughkeepsie | Food, Agriculture & Nutrition | $95K | $404K |
| 35 | Volunteer and Exempt Firemens Benevolent Association of | Unclassified | $93K | $469K |
| 36 | PTA New York Congress | Unclassified | $92K | $32K |
| 37 | Union Cemetery Association of Sayville INC | Unclassified | $89K | $816K |
| 38 | PTA New York Congress | Unclassified | $88K | $21K |
| 39 | Lions Club of Patchogue INC | Community Improvement & Capacity Building | $87K | $28K |
| 40 | Raiders Ice Hockey Club INC | Recreation & Sports | $84K | $25K |
| 41 | Restoration and Revival Center INC | Religion-Related | $74K | $5K |
| 42 | Jens Adoptable Cats INC | Animal-Related | $72K | $2K |
| 43 | Rachel Quinn Childrens Foundation INC | Education | $64K | $78K |
| 44 | Patchogue Neighbors Soup Kitchens INC | Food, Agriculture & Nutrition | $60K | $63K |
| 45 | Beading Hearts Overdose Loss Support Group INC | Mental Health & Crisis Intervention | $43K | $52K |
| 46 | Suffolk Boat Club INC | Unclassified | $33K | $69K |
| 47 | Dttb Angel Baby Corp. | Human Services | $25K | $7K |
| 48 | Kiwanis International INC | Unclassified | $20K | $12K |
| 49 | Professional Nurses Association of Suffolk County | Unclassified | $8K | $19K |
| 50 | Spotlight on Children INC | Youth Development | $8K | $20K |
| 51 | Courtney Lynn Blakeslee Foundation INC | Youth Development | $7K | $238K |
| 52 | Protecting Chrysalis INC | Youth Development | $2K | $1 |
| 53 | Suffolk County Lions Diabetes Educa Tion Foundation INC | Human Services | $1K | $54K |
| 54 | New Millennium Development Services INC | Community Improvement & Capacity Building | $1 | $154K |
| 55 | We Lead by Example INC | Human Services | $1 | $1 |
| 56 | Chabad of Patchogue INC | Religion-Related | $0 | $0 |
| 57 | St. Pauls Church | Unclassified | $0 | $0 |
| 58 | First Baptist Church | Religion-Related | $0 | $0 |
| 59 | Emanuel Lutheran Church | Unclassified | $0 | $0 |
| 60 | Patchogue Medford Friends of the Library | Education | $0 | $0 |
| 61 | Columbiettes Incorporated | Unclassified | $0 | $0 |
| 62 | Lutheran Church of Our Savior | Unclassified | $0 | $0 |
| 63 | Fraternal Order of Police | Crime & Legal-Related | $0 | $0 |
| 64 | Turning Point Church of the Nazarene | Unclassified | $0 | $0 |
| 65 | PTA New York Congress | Unclassified | $0 | $0 |
| 66 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 67 | National Council of Young Israel | Unclassified | $0 | $0 |
| 68 | German American Joint Action Comm | Unclassified | $0 | $0 |
| 69 | PTA New York Congress | Unclassified | $0 | $0 |
| 70 | East End Health Plan INC | Mutual & Membership Benefit | $0 | $0 |
| 71 | PTA New York Congress | Unclassified | $0 | $0 |
| 72 | PTA New York Congress | Unclassified | $0 | $0 |
| 73 | Suffolk School Emp Health Pl | Mutual & Membership Benefit | $0 | $0 |
| 74 | Grace Gospel Church of Suffolk | Unclassified | $0 | $0 |
| 75 | Harvest Tabernacle | Unclassified | $0 | $0 |
| 76 | Oasis Ministeries INC | Unclassified | $0 | $0 |
| 77 | Greater Patchogue Historical Society | Unclassified | $0 | $0 |
| 78 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 79 | Harvest Tabernacle | Unclassified | $0 | $0 |
| 80 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 81 | International Association of Lions Clubs | Unclassified | $0 | $0 |
| 82 | Island Christian Fellowship | Religion-Related | $0 | $0 |
| 83 | Congregation Mikveh of Eastern Long Island | Religion-Related | $0 | $0 |
| 84 | Protestant Campus Ministry at Suny Stony Brook | Religion-Related | $0 | $0 |
| 85 | Spanish Pentecostal Ch | Unclassified | $0 | $0 |
| 86 | Elsi Palmer Foundation | Diseases, Disorders & Medical Disciplines | $0 | $0 |
| 87 | Department of New York VFW Auxiliary | Public & Societal Benefit | $0 | $0 |
| 88 | Rotary International | Unclassified | $0 | $0 |
| 89 | Pilot Club of Patchogue INC | Unclassified | $0 | $0 |
| 90 | Steuben Society of America | Unclassified | $0 | $0 |
| 91 | PTA New York Congress | Education | $0 | $0 |
| 92 | Patchogue Hebrew Cemetery Association | Unclassified | $0 | $0 |
| 93 | American Legion | Unclassified | $0 | $0 |
| 94 | Steuben Society of America | Unclassified | $0 | $0 |
| 95 | Resurrection Christian Church | Unclassified | $0 | $0 |
| 96 | Steuben Endowment Corporation | Unclassified | $0 | $0 |
| 97 | Iglesia Bautista Luz de Las Naciones INC | Religion-Related | $0 | $0 |
| 98 | Psi Chi the National Honor Society in Psychology | Unclassified | $0 | $0 |
| 99 | PTA New York Congress | Unclassified | $0 | $0 |
| 100 | Knights of Columbus | Unclassified | $0 | $0 |