| 1 | Niagara Lutheran Development INC | Health Care | $25.1M | $25.5M |
| 2 | Greenfield Manor INC | Housing & Shelter | $7.3M | $20.0M |
| 3 | Lutheran Church Home of Buffalo INC | Human Services | $5.6M | $7.4M |
| 4 | Niagara Lutheran Home Foundation INC | Unclassified | $4.5M | $23.0M |
| 5 | Lancaster Volunteer Ambulance Corps INC | Health Care | $4.4M | $2.4M |
| 6 | Lutheran Church Home at Greenfield INC | Housing & Shelter | $3.4M | $1.5M |
| 7 | Lancaster Country Club INC | Unclassified | $3.1M | $3.5M |
| 8 | Niagara Lutheran Health Systems INC | Health Care | $1.2M | $21.6M |
| 9 | Twin District Volunteer Fire Company INC | Public Safety, Disaster Preparedness & Relief | $1.2M | $5.9M |
| 10 | Operation Exodus USA | Religion-Related | $1.2M | $2.2M |
| 11 | Childrens Rehabilitation Foundation of Variety Club of Buffalo INC | Unclassified | $1.2M | $856K |
| 12 | Lancaster New York Opera House INC | Arts, Culture & Humanities | $968K | $728K |
| 13 | Town Line Volunteer Fire Dept INC | Unclassified | $956K | $8.6M |
| 14 | Benevolent & Protective Order of Elks of the USA | Unclassified | $449K | $380K |
| 15 | Congo Leadership Initiative | International, Foreign Affairs & National Security | $394K | $105K |
| 16 | Depew Lodge No 1605 Loyal Order of Moose | Unclassified | $385K | $370K |
| 17 | Lancaster-depew Baseball League INC | Recreation & Sports | $380K | $281K |
| 18 | Buffalo and Western New York Soccer Boosters | Education | $293K | $440K |
| 19 | Greater Buffalo Adaptive Sports INC | Recreation & Sports | $274K | $108K |
| 20 | Hull House Foundation | Arts, Culture & Humanities | $266K | $1.8M |
| 21 | Lancaster-depew Ponytails Girls Softball INC | Recreation & Sports | $245K | $475K |
| 22 | Leonard Post Jr Post No 6251 INC | Unclassified | $201K | $952K |
| 23 | Lancaster Youth Football and Cheer INC | Youth Development | $170K | $292K |
| 24 | Annasor Answers INC | Human Services | $138K | $2K |
| 25 | Collaborative Center for Social Innovation INC | Youth Development | $134K | $81K |
| 26 | Lancaster Area Chamber of Commerce INC | Unclassified | $129K | $33K |
| 27 | Stony Brook Legendary Lights INC | Human Services | $120K | $2K |
| 28 | Lancaster Football Booster Club | Recreation & Sports | $115K | $46K |
| 29 | Whiting Family Foundation | Philanthropy, Voluntarism & Grantmaking | $114K | $561K |
| 30 | William Street School PTO | Education | $88K | $36K |
| 31 | American Federation of Teachers | Unclassified | $84K | $159K |
| 32 | Healing Tree Co | Arts, Culture & Humanities | $77K | $18K |
| 33 | Sundoulos INC | Human Services | $71K | $8K |
| 34 | Veterans of Foreign Wars of the United States Dept of New York | Unclassified | $71K | $17K |
| 35 | Variety Club Women of Buffalo Tent No 7 | Unclassified | $55K | $12K |
| 36 | Knights of Columbus | Unclassified | $46K | $346K |
| 37 | Branches Christian Rest and Renewal Centers INC | Religion-Related | $45K | $15K |
| 38 | Friends of Wny Volleyball INC | Recreation & Sports | $36K | $6K |
| 39 | Lancaster Educational and Alumni Foundation | Education | $29K | $160K |
| 40 | Joanne Ludtka Foundation INC | Medical Research | $18K | $15K |
| 41 | Vision Beyond Sight Foundation INC | Diseases, Disorders & Medical Disciplines | $17K | $126K |
| 42 | James Metz Memorial Fund Corporation | Recreation & Sports | $13K | $168K |
| 43 | Western New York Chapter of New York State Association of Health | Health Care | $3K | $3K |
| 44 | Como Park Elementary PTO | Education | $0 | $0 |
| 45 | Partnership for Children Youth and Families | Crime & Legal-Related | $0 | $0 |
| 46 | Department of New York VFW Auxiliary | Public & Societal Benefit | $0 | $0 |
| 47 | Lancaster Presbyterian Church | Unclassified | $0 | $0 |
| 48 | Buffalo Suburban Christian Academy | Unclassified | $0 | $0 |
| 49 | St. Johns Lutheran Church | Unclassified | $0 | $0 |
| 50 | St. Mary of the Assumption | Unclassified | $0 | $0 |
| 51 | American Federation of Teachers | Unclassified | $0 | $0 |
| 52 | Institute of Management Accountants INC | Unclassified | $0 | $0 |
| 53 | New Creation Fellowship of Buffalo | Unclassified | $0 | $0 |
| 54 | Lancaster New York Historical Society | Unclassified | $0 | $0 |
| 55 | Tree of Life Assembly of God | Unclassified | $0 | $0 |
| 56 | Love Joy Gospel Church | Religion-Related | $0 | $0 |
| 57 | Erie County Association of Cheifs of Police INC | Mutual & Membership Benefit | $0 | $0 |
| 58 | Spirit-word Ministries INC | Religion-Related | $0 | $0 |
| 59 | Christian Foundation for the Performing Arts | Arts, Culture & Humanities | $0 | $0 |
| 60 | Western New York Psychiatric Society | Community Improvement & Capacity Building | $0 | $0 |
| 61 | St. Marys High School | Unclassified | $0 | $0 |
| 62 | Chris Wanat Memorial Fund INC | Education | $0 | $0 |
| 63 | Unity Center for Unlimited Possibilities | Unclassified | $0 | $0 |
| 64 | Lancaster Youth Foundation Incorporated | Youth Development | $0 | $0 |
| 65 | Bowmansville Garden Club | Environment | $0 | $0 |
| 66 | Lancaster Lax Association INC | Recreation & Sports | $0 | $0 |
| 67 | Buffalo and Erie County Public Library Co | Unclassified | $0 | $0 |
| 68 | Brotherhood of Locomotive Engineers and Trainmen | Unclassified | $0 | $0 |
| 69 | Society for Preservation & Encourmt of Barbershop Quartet Singing Amer | Arts, Culture & Humanities | $0 | $0 |
| 70 | Rotary International | Unclassified | $0 | $0 |
| 71 | Polish Cultural Foundation INC | Unclassified | $0 | $0 |
| 72 | Greater Lancaster Fire Prevention and Prevention Organization INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 73 | Broadway Hope INC | Religion-Related | $0 | $0 |
| 74 | Federated Garden Clubs of New York State INC | Environment | $0 | $0 |
| 75 | Western New York Regents Round Table District 8 | Arts, Culture & Humanities | $0 | $0 |
| 76 | Depew Lancaster Chapt No 2323 Women of the Moose | Unclassified | $0 | $0 |
| 77 | Gfwc New York State Federation of Womens Club | Unclassified | $0 | $0 |
| 78 | Lions Club of Lancaster INC | Community Improvement & Capacity Building | $0 | $0 |
| 79 | First Baptist Church Lancaster | Unclassified | $0 | $0 |
| 80 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 81 | Amvets | Unclassified | $0 | $0 |
| 82 | International Police Association United States Section INC | Unclassified | $0 | $0 |
| 83 | The United States Pony Clubs INC | Recreation & Sports | $0 | $0 |
| 84 | Town Line Volunteer Firemens Benevolent Association Erie County | Unclassified | $0 | $0 |
| 85 | Lutheran Womens Missionary League | Unclassified | $0 | $0 |
| 86 | Department of New York VFW Auxiliary | Public & Societal Benefit | $0 | $0 |
| 87 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 88 | Collins Christian Ministries | Religion-Related | $0 | $0 |
| 89 | Melcher Boling Cares Corp. | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 90 | Ivdd Awareness Foundation | Animal-Related | $0 | $0 |
| 91 | Seek First Foundation INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 92 | Artsbuffalo INC | Arts, Culture & Humanities | $0 | $0 |
| 93 | Society of Gastroenterology Nurses and Associates INC | Unclassified | $0 | $0 |
| 94 | Deer Search of Wny Incorporated | Public & Societal Benefit | $0 | $0 |
| 95 | Live Like Steve INC | Human Services | $0 | $0 |
| 96 | Carnival Kids Steel Orchestra Boost Ers Incorporated | Arts, Culture & Humanities | $0 | $0 |
| 97 | Parent Booster USA INC | Unclassified | $0 | $0 |
| 98 | Jim Bistoff Memorial Foundation INC | Environment | $0 | $0 |
| 99 | The Friends of the Lancaster Public Library INC | Education | $0 | $0 |
| 100 | Women of the World Transition Center of Western New York INC | Crime & Legal-Related | $0 | $0 |