| 1 | Aspire of Western New York INC | Housing & Shelter | $95.3M | $42.8M |
| 2 | Horizon Health Services INC | Mental Health & Crisis Intervention | $63.6M | $38.5M |
| 3 | Summit Center INC | Education | $36.1M | $30.7M |
| 4 | Foundation for Jewish Philanthropies | Philanthropy, Voluntarism & Grantmaking | $33.3M | $271.4M |
| 5 | Beechwood Health Care Center INC | Health Care | $30.6M | $29.4M |
| 6 | Peter & Elizabeth C Tower Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $27.0M | $121.1M |
| 7 | Horizon Village INC | Unclassified | $23.7M | $15.9M |
| 8 | Fallon Health Weinberg INC | Human Services | $19.8M | $41.7M |
| 9 | Rosa Coplon Jewish Home and Infirmary | Health Care | $15.8M | $2.6M |
| 10 | Jewish Community Center of Greater Buffalo INC | Human Services | $13.1M | $20.5M |
| 11 | Health Management Group Ltd | Philanthropy, Voluntarism & Grantmaking | $11.1M | $9.3M |
| 12 | Asbury Points INC | Housing & Shelter | $9.6M | $36.3M |
| 13 | Beechwood Continuing Care INC | Health Care | $3.6M | $1.2M |
| 14 | Getzville Fire Company INC | Public Safety, Disaster Preparedness & Relief | $1.6M | $7.5M |
| 15 | Aspire of Western New York INC | Housing & Shelter | $1.5M | $6.9M |
| 16 | The Beechwood Blocher Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.2M | $4.6M |
| 17 | Discovery Kids Learning Center INC | Human Services | $1.0M | $446K |
| 18 | Aspire Foundation | Diseases, Disorders & Medical Disciplines | $856K | $3.5M |
| 19 | Ub Amherst Swimming INC | Recreation & Sports | $364K | $121K |
| 20 | Summit Foundation INC | Philanthropy, Voluntarism & Grantmaking | $351K | $1.6M |
| 21 | Hindu Cultural Society of Western New York | Unclassified | $324K | $1.1M |
| 22 | Jacquie Hirsch for All Foundation | Education | $241K | $692K |
| 23 | Luminina Corp. | Health Care | $198K | $417K |
| 24 | Chinese Club of Western New York | Unclassified | $180K | $250K |
| 25 | Williamsville Junior Football INC | Recreation & Sports | $171K | $85K |
| 26 | Temple Beth el Cemetery Corporation | Mutual & Membership Benefit | $149K | $641K |
| 27 | Kadimah School of Buffalo | Unclassified | $146K | $2.9M |
| 28 | Vaad Hakashrus of Buffalo INC | Religion-Related | $102K | $135K |
| 29 | Transformation Ballet INC | Arts, Culture & Humanities | $57K | $48K |
| 30 | William S Hein & Company Foundation | Philanthropy, Voluntarism & Grantmaking | $51K | $618K |
| 31 | Hopeful Ways INC | Religion-Related | $45K | $61K |
| 32 | Buffalo Niagara Choirs INC | Arts, Culture & Humanities | $40K | $29K |
| 33 | Kennel Club of Niagara Falls INC | Recreation & Sports | $27K | $120K |
| 34 | Western New York Hispanic American Veterans Memorial INC | Community Improvement & Capacity Building | $24K | $52K |
| 35 | Coalition of Adoption and Foster Family Agencies | Human Services | $14K | $56K |
| 36 | Braille Group of Buffalo Incorporated | Human Services | $12K | $170K |
| 37 | Friends of Jesus Foundation | Philanthropy, Voluntarism & Grantmaking | $9K | $1 |
| 38 | Hebrew Benevolent Loan Association | Unclassified | $6K | $271K |
| 39 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 40 | The Chapel at Crosspoint | Unclassified | $0 | $0 |
| 41 | Bais Lubavitch INC | Religion-Related | $0 | $0 |
| 42 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 43 | Basileia Missions INC | Human Services | $0 | $0 |
| 44 | Aspire of Western New York Ing | Housing & Shelter | $0 | $0 |
| 45 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 46 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 47 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 48 | St. Pius X R C Church | Unclassified | $0 | $0 |
| 49 | Air Force Association | Education | $0 | $0 |
| 50 | Buffalo Asthma Allergy Society INC | Community Improvement & Capacity Building | $0 | $0 |
| 51 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 52 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 53 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 54 | Western New York Association of Historical Agencies | Unclassified | $0 | $0 |
| 55 | Scalp and Blade Incorporated | Unclassified | $0 | $0 |
| 56 | Air Force Association | Education | $0 | $0 |
| 57 | Islamic Society of Niagara Frontier | Unclassified | $0 | $0 |
| 58 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 59 | Bhairavi Fine Arts INC | Arts, Culture & Humanities | $0 | $0 |
| 60 | Value Network INC | Health Care | $0 | $0 |
| 61 | Kc Community Development INC | Community Improvement & Capacity Building | $0 | $0 |
| 62 | Buffalo Chinese Language Center | Arts, Culture & Humanities | $0 | $0 |
| 63 | International Sustainable Livelihood Foundation Incorporated | International, Foreign Affairs & National Security | $0 | $0 |
| 64 | Alix Rice Peace Park Foundation INC | Recreation & Sports | $0 | $0 |
| 65 | Ssg William R Wilson III Memorial Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 66 | Buffalo Goes Gray | Human Services | $0 | $0 |
| 67 | The Wellbuffalo Bethel Campus | Unclassified | $0 | $0 |
| 68 | Butterfly Moon INC | Arts, Culture & Humanities | $0 | $0 |
| 69 | Amherst Drug Court & Therapeutic Foundation INC | Mental Health & Crisis Intervention | $0 | $0 |
| 70 | Charities United Organization | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 71 | Christopher Maloney Legacy Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 72 | Fellowship Baptist Church of Amherst | Religion-Related | $0 | $0 |
| 73 | Aspire of Western New York INC | Housing & Shelter | $0 | $0 |
| 74 | New York Coalition for Open Government | Public & Societal Benefit | $0 | $0 |
| 75 | Iron Therapy INC | Public & Societal Benefit | $0 | $0 |
| 76 | Sadie Strong | Community Improvement & Capacity Building | $0 | $0 |
| 77 | Parent Booster USA INC | Education | $0 | $0 |
| 78 | Buffalo Association of Substitute Administrators | Employment | $0 | $0 |
| 79 | Amherst Helping Hands INC | Human Services | $0 | $0 |
| 80 | Sharks Cricket Association INC | Recreation & Sports | $0 | $0 |
| 81 | Friends of Amherst Youth Hockey INC | Recreation & Sports | $0 | $302K |
| 82 | 716 Herd INC | Unclassified | $0 | $0 |
| 83 | Civil Service Employees Association | Unclassified | $0 | $0 |