| 1 | Walter Scott Family Foundation | Philanthropy, Voluntarism & Grantmaking | $7.1B | $2.8B |
| 2 | Woodmen of the World Life Insurance Society | Unclassified | $2.4B | $11.3B |
| 3 | The Susan Thompson Buffett Foundation | Philanthropy, Voluntarism & Grantmaking | $2.4B | $2.8B |
| 4 | The Nebraska Medical Center | Health Care | $2.3B | $2.3B |
| 5 | Creighton University | Education | $1.3B | $2.0B |
| 6 | Suzanne and Walter Scott Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2B | $965.1M |
| 7 | Nebraska Methodist Hospital | Health Care | $1.0B | $1.1B |
| 8 | Childrens Hospital & Medical Center | Health Care | $997.9M | $1.6B |
| 9 | Alegent Health - Bergan Mercy Health System | Health Care | $804.3M | $1.1B |
| 10 | Sherwood Foundation | Philanthropy, Voluntarism & Grantmaking | $655.1M | $716.3M |
| 11 | Alegent Creighton Clinic | Health Care | $580.6M | $131.0M |
| 12 | Eagle Foundation | Unclassified | $576.6M | $990.9M |
| 13 | Unmc Physicians | Health Care | $564.5M | $178.4M |
| 14 | Peter Kiewit Foundation | Philanthropy, Voluntarism & Grantmaking | $556.3M | $466.6M |
| 15 | Alegent Creighton Health | Health Care | $488.1M | $839.0M |
| 16 | Mosaic | Housing & Shelter | $374.9M | $227.1M |
| 17 | Physicians Clinic INC | Health Care | $306.9M | $108.3M |
| 18 | Omaha Community Foundation | Philanthropy, Voluntarism & Grantmaking | $258.0M | $556.1M |
| 19 | Alegent Health-immanuel Medical Center | Health Care | $235.8M | $805.8M |
| 20 | Methodist Fremont Health | Health Care | $198.9M | $176.2M |
| 21 | Filkins Family Foundation | Philanthropy, Voluntarism & Grantmaking | $162.6M | $137.6M |
| 22 | Nebraska Medicine | Health Care | $141.5M | $1.4B |
| 23 | Omaha Community Foundation Donor Directed Depository | Philanthropy, Voluntarism & Grantmaking | $134.9M | $63.6M |
| 24 | Nebraska Methodist Health System INC | Health Care | $134.2M | $2.0B |
| 25 | First National of Nebraska INC Welfare Benefit Plan Trust | Mutual & Membership Benefit | $130.4M | $1.1M |
| 26 | The Lozier Foundation | Philanthropy, Voluntarism & Grantmaking | $129.6M | $437.1M |
| 27 | The Hawks Foundation | Education | $123.8M | $413.1M |
| 28 | Nebraska Pediatric Practice INC | Health Care | $112.4M | $22.7M |
| 29 | William and Ruth Scott Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $104.5M | $214.6M |
| 30 | Metropolitan Entertainment & | Community Improvement & Capacity Building | $101.6M | $134.4M |
| 31 | Nebraska Methodist Hospital Foundation | Health Care | $99.6M | $175.5M |
| 32 | Omaha Zoological Society INC | Animal-Related | $91.2M | $340.4M |
| 33 | Edward and Sally@malashock Family Foundation | Philanthropy, Voluntarism & Grantmaking | $88.9M | $83.7M |
| 34 | Oneworld Community Health Centers INC | Unclassified | $79.8M | $82.4M |
| 35 | Momentum Housing | Housing & Shelter | $74.1M | $614.2M |
| 36 | Immanuel Retirement Communities | Housing & Shelter | $73.7M | $168.6M |
| 37 | Childrens Physicians | Health Care | $73.6M | $17.5M |
| 38 | The Giving 3 Foundation | Philanthropy, Voluntarism & Grantmaking | $73.4M | $92.6M |
| 39 | Robert B Daugherty Foundation | Unclassified | $73.4M | $839.7M |
| 40 | IBEW Neca Health and Welfare Fund | Unclassified | $72.6M | $57.8M |
| 41 | Foodbank for the Heartland | Unclassified | $64.3M | $51.5M |
| 42 | Unmc Science Research Fund | Science & Technology | $64.1M | $207.4M |
| 43 | Goodwill Industries INC | Employment | $63.7M | $71.0M |
| 44 | Immanuel | Health Care | $61.8M | $774.7M |
| 45 | Clarkson Regional Health Services INC | Health Care | $57.7M | $1.0B |
| 46 | Mutual of Omaha Foundation | Philanthropy, Voluntarism & Grantmaking | $55.5M | $113.1M |
| 47 | Pace Iowa | Health Care | $52.1M | $12.9M |
| 48 | Jewish Federation of Omaha INC | Philanthropy, Voluntarism & Grantmaking | $49.5M | $64.7M |
| 49 | Mammel Family Foundation | Philanthropy, Voluntarism & Grantmaking | $49.3M | $127.0M |
| 50 | Omaha Performing Arts Society | Arts, Culture & Humanities | $48.7M | $43.3M |
| 51 | Opas Foundation | Arts, Culture & Humanities | $44.6M | $322.7M |
| 52 | Harper Family Foundation | Unclassified | $44.3M | $169.1M |
| 53 | Omaha Zoo Foundation | Animal-Related | $43.2M | $185.8M |
| 54 | Omaha Home for Boys | Human Services | $43.2M | $88.8M |
| 55 | Quality Living INC | Health Care | $43.0M | $83.3M |
| 56 | Delta Dental of Nebraska | Unclassified | $42.5M | $16.1M |
| 57 | Community Alliance INC | Unclassified | $40.0M | $87.5M |
| 58 | Project Harmony-haven for Abuse Response Members Serving Our | Crime & Legal-Related | $39.3M | $58.2M |
| 59 | Habitat for Humanity International INC | Housing & Shelter | $39.2M | $68.1M |
| 60 | Clarkson College | Unclassified | $38.4M | $36.0M |
| 61 | Steamfitters Local Union 464 Welfare Fund | Unclassified | $38.0M | $42.4M |
| 62 | Buffett Early Childhood Fund | Philanthropy, Voluntarism & Grantmaking | $37.5M | $9.0M |
| 63 | Charles and Mary Heider Family Foundation | Philanthropy, Voluntarism & Grantmaking | $37.4M | $271.6M |
| 64 | Lutheran Family Services of Ne INC | Human Services | $37.2M | $36.0M |
| 65 | United Way of the Midlands | Philanthropy, Voluntarism & Grantmaking | $32.0M | $23.9M |
| 66 | Open Door Mission | Human Services | $31.0M | $36.1M |
| 67 | YMCA of Greater Omaha | Human Services | $30.9M | $62.6M |
| 68 | Nebraska Methodist College of Nursing and Allied Health | Unclassified | $28.9M | $48.5M |
| 69 | Outlook-nebraska INC | Employment | $28.5M | $38.0M |
| 70 | Pace Nebraska | Health Care | $26.8M | $5.5M |
| 71 | Joslyn Art Museum | Arts, Culture & Humanities | $26.7M | $140.6M |
| 72 | Omni Behavioral Health | Philanthropy, Voluntarism & Grantmaking | $24.5M | $20.5M |
| 73 | Immanuel Long Term Care | Health Care | $24.1M | $53.8M |
| 74 | John and Elizabeth Lauritzen Foundation | Unclassified | $24.0M | $85.3M |
| 75 | College of St. Mary | Education | $23.9M | $100.2M |
| 76 | Mental Health Innovation Foundation | Health Care | $23.8M | $116.3M |
| 77 | Boys & Girls Clubs of the Midlands | Youth Development | $23.3M | $50.2M |
| 78 | Nebraska Humane Society | Animal-Related | $23.1M | $77.8M |
| 79 | Omaha Childrens Trust | Arts, Culture & Humanities | $22.9M | $22.7M |
| 80 | Nebraska Organ Recovery System | Health Care | $22.7M | $21.3M |
| 81 | Child Saving Institute Foundation INC | Philanthropy, Voluntarism & Grantmaking | $22.4M | $54.0M |
| 82 | Charles Drew Health Center INC | Health Care | $22.2M | $20.8M |
| 83 | The Mosaic Foundation | Human Services | $21.6M | $68.8M |
| 84 | Jewish Federation of Omaha Foundation | Philanthropy, Voluntarism & Grantmaking | $21.6M | $130.8M |
| 85 | Omaha Firefighters Healthcare Trust | Mutual & Membership Benefit | $21.3M | $6.3M |
| 86 | Childrens Hospital & Medical Center Foundation | Health Care | $21.1M | $57.7M |
| 87 | Claire M Hubbard Foundation | Philanthropy, Voluntarism & Grantmaking | $20.7M | $26.6M |
| 88 | Midwest Housing Equity Group INC | Housing & Shelter | $20.7M | $76.6M |
| 89 | Justice for Our Neighbors Nebraska | Human Services | $20.4M | $23.5M |
| 90 | Weitz Family Foundation | Philanthropy, Voluntarism & Grantmaking | $19.8M | $21.2M |
| 91 | Educare of Omaha INC | Education | $19.7M | $17.8M |
| 92 | Westside Community Schools Foundation INC | Education | $18.9M | $16.2M |
| 93 | Amy L Scott Family Foundation | Philanthropy, Voluntarism & Grantmaking | $18.2M | $49.4M |
| 94 | Board of Certification INC | Unclassified | $18.1M | $26.5M |
| 95 | Together INC of Metropolitian Omaha | Human Services | $18.1M | $12.2M |
| 96 | Irc II INC | Housing & Shelter | $18.0M | $64.7M |
| 97 | Parker Family Foundation | Philanthropy, Voluntarism & Grantmaking | $18.0M | $49.5M |
| 98 | Millard Public Schools Foundation INC | Human Services | $17.9M | $31.5M |
| 99 | Siena Francis House | Housing & Shelter | $17.8M | $38.3M |
| 100 | Omaha Botanical Center INC | Environment | $17.7M | $97.3M |