| 1 | Freeman Health System | Health Care | $795.1M | $734.7M |
| 2 | Mercy Hospital Joplin | Health Care | $308.7M | $174.7M |
| 3 | Mercy Health Southwest Missouri Kansas Communities | Unclassified | $69.9M | $9.6M |
| 4 | Ozark Center | Mental Health & Crisis Intervention | $67.7M | $158.2M |
| 5 | J P Humphreys Foundation INC | Unclassified | $44.1M | $32.7M |
| 6 | Christ in Youth INC | Unclassified | $33.6M | $8.0M |
| 7 | Jasper County Sheltered Facilities Association | Unclassified | $28.7M | $20.2M |
| 8 | Economic Security Corporation of Southwest Area | Unclassified | $22.0M | $8.7M |
| 9 | Missouri Southern Foundation | Education | $17.1M | $62.7M |
| 10 | E L Craig Foundation | Unclassified | $15.6M | $6.9M |
| 11 | Greater Joplin Area Emergency Medical Services System INC | Unclassified | $8.6M | $8.8M |
| 12 | Joplin Historical Neighborhoods INC | Public Safety, Disaster Preparedness & Relief | $8.3M | $26.3M |
| 13 | Victory Ministry & Sports Complex | Religion-Related | $7.6M | $5.6M |
| 14 | Rapha House International INC | Crime & Legal-Related | $5.4M | $10.1M |
| 15 | New Heights Christian Academy | Education | $5.3M | $4.0M |
| 16 | Thomas Jefferson Independent Day School | Education | $5.2M | $12.9M |
| 17 | Area Agency on Aging Region X | Human Services | $5.0M | $2.3M |
| 18 | International Bible Association | Religion-Related | $4.4M | $6.0M |
| 19 | Family Self Help Center INC | Unclassified | $4.1M | $3.2M |
| 20 | The Independent Living Center INC | Arts, Culture & Humanities | $3.8M | $8.2M |
| 21 | Refugee and Immigrant Services & Education | Human Services | $3.6M | $640K |
| 22 | Safe and Sound a Sandy Hook Initiative INC | Crime & Legal-Related | $3.5M | $1.4M |
| 23 | Habitat for Humanity International INC | Unclassified | $3.4M | $8.0M |
| 24 | Watered Gardens | Human Services | $3.1M | $4.7M |
| 25 | Work Force Investment Board of the Southwest Region INC | Community Improvement & Capacity Building | $2.8M | $357K |
| 26 | Twin Hills Golf & Country Club INC | Unclassified | $2.8M | $4.0M |
| 27 | Joplin Family Y | Human Services | $2.6M | $5.9M |
| 28 | Lifechoices | Health Care | $2.4M | $4.4M |
| 29 | Joplin Humane Society INC | Animal-Related | $2.3M | $7.6M |
| 30 | Childrens Center | Crime & Legal-Related | $2.1M | $5.1M |
| 31 | Community Clinic of Southwest Missouri | Unclassified | $2.1M | $1.6M |
| 32 | Crosslines Churches of the Joplin Area INC | Human Services | $2.1M | $1.1M |
| 33 | Boys and Girls Club of Joplin Missouri | Youth Development | $1.8M | $3.5M |
| 34 | Mercy Health Foundation Joplin | Unclassified | $1.7M | $7.8M |
| 35 | Joplin Workshops INC | Employment | $1.6M | $344K |
| 36 | Southwest Missouri Community Alliance | Recreation & Sports | $1.6M | $2.2M |
| 37 | American Rehabilitation Ministry INC | Crime & Legal-Related | $1.5M | $2.0M |
| 38 | Gods Resort INC | Housing & Shelter | $1.4M | $2.2M |
| 39 | Joplin Area Chamber of Commerce | Unclassified | $1.3M | $506K |
| 40 | Jasper County Casa | Crime & Legal-Related | $1.3M | $3.4M |
| 41 | Ronald McDonald House Charities of the Four States | Health Care | $1.2M | $4.4M |
| 42 | Life of Hope Ministries | International, Foreign Affairs & National Security | $1.1M | $272K |
| 43 | Willcoxon Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.1M | $2.0M |
| 44 | United Way of Southwest Missouri and Southeast Kansas INC | Community Improvement & Capacity Building | $1.0M | $2.1M |
| 45 | Childrens Haven of Sw Missouri | Youth Development | $1.0M | $3.3M |
| 46 | Joplin Area Chamber of Commerce Foundation | Education | $924K | $4.5M |
| 47 | Missouri Parents Act | Unclassified | $904K | $364K |
| 48 | International Brotherhood of Electrical Workers | Unclassified | $869K | $1.8M |
| 49 | Connect2culture | Arts, Culture & Humanities | $828K | $502K |
| 50 | Benevolent & Protective Order of Elks of the USA | Unclassified | $777K | $1.4M |
| 51 | Mercy Auxiliary Joplin | Unclassified | $696K | $638K |
| 52 | Harry M Cornell Arts & Entertainment Complex | Arts, Culture & Humanities | $638K | $19.9M |
| 53 | Joplin Sports Authority INC | Recreation & Sports | $614K | $112K |
| 54 | Blackbox International | International, Foreign Affairs & National Security | $611K | $147K |
| 55 | Compass Academy Network INC | Education | $601K | $18K |
| 56 | Creative Learning Alliance INC | Community Improvement & Capacity Building | $573K | $1.6M |
| 57 | Higher Power Garage | Public Safety, Disaster Preparedness & Relief | $564K | $571K |
| 58 | White Fields Overseas Evangelism INC | Religion-Related | $557K | $29K |
| 59 | Odessa Senior Citizens INC | Unclassified | $542K | $902K |
| 60 | Solace House of the Ozarks INC | Human Services | $536K | $536K |
| 61 | Main Street Joplin | Community Improvement & Capacity Building | $516K | $2.2M |
| 62 | George a Spiva Center for the Arts | Arts, Culture & Humanities | $506K | $1.5M |
| 63 | Dayspring Outreach Ministries | Religion-Related | $483K | $227K |
| 64 | Peterson Outdoors Ministries | Human Services | $466K | $1.7M |
| 65 | Ascent Recovery Residences INC | Mental Health & Crisis Intervention | $464K | $585K |
| 66 | Mwangaza International | International, Foreign Affairs & National Security | $449K | $353K |
| 67 | Pleasant Hill Housing & Development Corp. | Unclassified | $444K | $1.1M |
| 68 | International Brotherhood of Teamsters | Unclassified | $441K | $499K |
| 69 | Warsaw Senior Citizens Housing Association | Unclassified | $439K | $1.5M |
| 70 | Peculiar Sr Citizen Housing INC | Housing & Shelter | $432K | $1.0M |
| 71 | Jennings Family Foundation | Philanthropy, Voluntarism & Grantmaking | $422K | $3.2M |
| 72 | Train International | Religion-Related | $413K | $122K |
| 73 | California Senior Housing Association INC | Unclassified | $406K | $1.2M |
| 74 | Greenfield Retirement Home INC | Unclassified | $401K | $887K |
| 75 | Christians for World Peace | Religion-Related | $393K | $839K |
| 76 | Harry S Truman Community Development Corporation | Housing & Shelter | $373K | $5.0M |
| 77 | W R Corley Memorial Trust | Philanthropy, Voluntarism & Grantmaking | $366K | $4.2M |
| 78 | Drexel Development Corporation | Unclassified | $351K | $591K |
| 79 | Birch Tree Housing Corporation | Housing & Shelter | $328K | $1.1M |
| 80 | Archie Senior Housing INC | Unclassified | $327K | $921K |
| 81 | Christ to the Nations | Religion-Related | $315K | $101K |
| 82 | International Brotherhood of Electrical Workers | Unclassified | $314K | $536K |
| 83 | Paws with Possibilities Pet Rescue and Care Center | Animal-Related | $298K | $54K |
| 84 | Buffalo Area Community Housing Corporation | Unclassified | $293K | $1.2M |
| 85 | Harrisonville Senior Citizens Housing INC | Unclassified | $292K | $3.5M |
| 86 | El Dorado Springs Housing INC | Unclassified | $290K | $444K |
| 87 | Veterans of Foreign Wars Dept of Missouri | Unclassified | $288K | $431K |
| 88 | Rk Missions | Human Services | $285K | $532K |
| 89 | Bright Futures Joplin | Human Services | $275K | $482K |
| 90 | Willard Retirement Village INC | Unclassified | $275K | $453K |
| 91 | 4 States Youth Athletics Association | Arts, Culture & Humanities | $269K | $1.9M |
| 92 | West Side Homes INC | Unclassified | $266K | $380K |
| 93 | Souls Harbor of America INC | Unclassified | $263K | $337K |
| 94 | Ancient & Accepted Scottish Rite of Free Masonry So Juris USA | Unclassified | $262K | $1.2M |
| 95 | Carroll County Housing Development | Unclassified | $260K | $2.3M |
| 96 | Crane Senior Citizens Housing Association | Unclassified | $253K | $360K |
| 97 | Dixon Community Housing Corp. | Unclassified | $241K | $466K |
| 98 | Humansville Senior Citizens Housing Corp. | Unclassified | $241K | $738K |
| 99 | Meadow Brook Manor INC | Unclassified | $239K | $660K |
| 100 | School District of Joplin R-viii Foundation | Unclassified | $238K | $888K |