| 1 | Southeast Missouri Network Against Sexual Violence INC | Human Services | $1.4M | $792K |
| 2 | Benevolent & Protective Order of Elks of the USA | Unclassified | $697K | $437K |
| 3 | Jackson Senior Center | Human Services | $602K | $146K |
| 4 | American Legion | Unclassified | $541K | $315K |
| 5 | Safe Harbor Animal Sanctuary | Animal-Related | $494K | $1.1M |
| 6 | Jackson Area Chamber of Commerce | Unclassified | $482K | $940K |
| 7 | Project 200 | Religion-Related | $430K | $408K |
| 8 | Uptown Jackson Revitalization Organization INC | Community Improvement & Capacity Building | $405K | $370K |
| 9 | Breaking Bonds Ministries - Jackson | Employment | $399K | $581K |
| 10 | Jaosa INC | Recreation & Sports | $381K | $88K |
| 11 | Jackson R-2 School District Foundation | Education | $373K | $1.9M |
| 12 | River City Aquatics | Recreation & Sports | $215K | $26K |
| 13 | Iron Mountain Railway | Arts, Culture & Humanities | $182K | $337K |
| 14 | Cape Girardeau County Historical Society | Arts, Culture & Humanities | $130K | $318K |
| 15 | Essex Npd Corporation | Unclassified | $89K | $147K |
| 16 | Hfc House INC | Human Services | $78K | $404K |
| 17 | The Rushing Family Tr | Human Services | $70K | $321K |
| 18 | Missouri Association of Colleges for Teacher Education | Unclassified | $70K | $125K |
| 19 | My Team Triumph INC | Human Services | $63K | $44K |
| 20 | Optimist International | Unclassified | $61K | $223K |
| 21 | Bottom Seam Aces Baseball | Youth Development | $61K | $8K |
| 22 | Knights of Columbus | Unclassified | $57K | $58K |
| 23 | Semo Lawyers Library INC | Unclassified | $54K | $135K |
| 24 | Optimist International | Unclassified | $53K | $237K |
| 25 | Sarahs Gift | Youth Development | $37K | $197K |
| 26 | Charles D & Sue C Crites Foundation | Food, Agriculture & Nutrition | $35K | $85K |
| 27 | Jackson Senior Citizens Foundation INC | Human Services | $33K | $1.8M |
| 28 | Southeast Missouri District Fair Association INC | Unclassified | $13K | $2.2M |
| 29 | St. Paul Lutheran School Foundation | Education | $6K | $283K |
| 30 | Buttheadz Growers Club | Environment | $2K | $812 |
| 31 | Bstrong Forever Foundation | Public & Societal Benefit | $500 | $1K |
| 32 | Mercy Hill Church | Unclassified | $0 | $0 |
| 33 | Onward for Christ Evangelistic Association INC | Unclassified | $0 | $0 |
| 34 | Boy Scouts of America | Youth Development | $0 | $0 |
| 35 | Jesus Anoints Ministries | Religion-Related | $0 | $0 |
| 36 | Spec- Ops Plaza INC | Arts, Culture & Humanities | $0 | $0 |
| 37 | Veterans of Foreign Wars Dept of Missouri | Unclassified | $0 | $0 |
| 38 | Ancient Free & Accepted Masons of Missouri | Unclassified | $0 | $0 |
| 39 | Ancient Free & Accepted Masons of Missouri | Unclassified | $0 | $0 |
| 40 | Ancient Free & Accepted Masons of Missouri | Unclassified | $0 | $0 |
| 41 | Demolay International | Arts, Culture & Humanities | $0 | $0 |
| 42 | National Society of the Children of the American Revolution | Unclassified | $0 | $0 |
| 43 | Cape Youth Tackle Football | Recreation & Sports | $0 | $0 |
| 44 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 45 | Cape Girardeau County Extension Foundation INC | Food, Agriculture & Nutrition | $0 | $0 |
| 46 | Ur Home Ministries | Housing & Shelter | $0 | $0 |
| 47 | Bridge Reunification Services | Education | $0 | $0 |
| 48 | Rca Booster Club | Youth Development | $0 | $0 |
| 49 | Ed-ventures in Missions | Arts, Culture & Humanities | $0 | $0 |
| 50 | Friends 4 Life | Recreation & Sports | $0 | $0 |
| 51 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 52 | Cape Girardeau County Farm Bureau | Unclassified | $0 | $0 |
| 53 | St. Paul Lutheran Church | Unclassified | $0 | $0 |
| 54 | New McKendree United Methodist Church | Unclassified | $0 | $0 |
| 55 | United Food and Commercial Workers International Union | Unclassified | $0 | $0 |
| 56 | Jackson Community Foundation INC | Community Improvement & Capacity Building | $0 | $0 |
| 57 | New Bethel Baptist Church Jackson | Unclassified | $0 | $0 |
| 58 | German Evangelical Church & Cemetery Association INC | Unclassified | $0 | $0 |
| 59 | Shawnee Hills Baptist Church | Unclassified | $0 | $0 |
| 60 | Fountain of Life Tabernacle | Unclassified | $0 | $0 |
| 61 | Good News Christian Center | Unclassified | $0 | $0 |
| 62 | Jackson Heritage Association Incorporated | Arts, Culture & Humanities | $0 | $0 |
| 63 | Cape Girardeau County Gun Club | Recreation & Sports | $0 | $0 |
| 64 | Mafce INC | Unclassified | $0 | $0 |
| 65 | Mafce INC | Unclassified | $0 | $0 |
| 66 | Mafce INC | Unclassified | $0 | $0 |
| 67 | Mafce INC | Unclassified | $0 | $0 |
| 68 | Mafce INC | Unclassified | $0 | $0 |
| 69 | Mafce INC | Unclassified | $0 | $0 |
| 70 | Mafce INC | Unclassified | $0 | $0 |
| 71 | Mafce INC | Unclassified | $0 | $0 |
| 72 | First Baptist Church Jackson | Unclassified | $0 | $0 |
| 73 | Optimist International | Unclassified | $0 | $0 |
| 74 | Covenant Life Church | Unclassified | $0 | $0 |
| 75 | Jackson Church of the Nazarene | Unclassified | $0 | $0 |
| 76 | Brookside Park Memorial to Veterans of All Wars | Unclassified | $0 | $0 |
| 77 | Jackson Congregational Methodist Mission | Unclassified | $0 | $0 |
| 78 | West Lane Elementary PTO | Education | $0 | $0 |
| 79 | National Society of the Sons of the American Revolution | Human Services | $0 | $0 |
| 80 | Camp Semo Wappapello | Unclassified | $0 | $0 |
| 81 | Fruitland Church of Christ | Religion-Related | $0 | $0 |
| 82 | Fruitland Community Church | Religion-Related | $0 | $0 |
| 83 | Saxony Lutheran High School | Education | $0 | $0 |
| 84 | Cape Girardeau County Genealogical Society | Arts, Culture & Humanities | $0 | $0 |
| 85 | Immanuel Lutheran Church | Unclassified | $0 | $0 |
| 86 | American Legion Auxiliary | Unclassified | $0 | $0 |
| 87 | Cape Girardeau Baptist Association | Unclassified | $0 | $0 |
| 88 | National Society of the Daughters of the American Revolution | Unclassified | $0 | $0 |
| 89 | Brotherhood of Locomotive Engineers and Trainmen | Unclassified | $0 | $0 |
| 90 | Rotary International | Unclassified | $0 | $0 |
| 91 | Missouri Nursing Student Association | Unclassified | $0 | $0 |
| 92 | Disabled American Veterans | Unclassified | $0 | $0 |
| 93 | Cape Girardeau Masonic Temple Association | Unclassified | $0 | $0 |
| 94 | Gospel Chapel | Unclassified | $0 | $0 |
| 95 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 96 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 97 | River of God Healing Ministries INC | Religion-Related | $0 | $0 |
| 98 | Room for Smiles | Health Care | $0 | $0 |
| 99 | Friends of Wyatt | Medical Research | $0 | $0 |
| 100 | Believing Beyond - the Nolan Weber Foundation | Public & Societal Benefit | $0 | $0 |