| 1 | McLaren Health Plan INC | Health Care | $1.2B | $461.2M |
| 2 | Charles Stewart Mott Foundation | Philanthropy, Voluntarism & Grantmaking | $862.0M | $3.8B |
| 3 | McLaren Flint | Health Care | $567.0M | $604.5M |
| 4 | Credit Unions Chartered in the State of Michigan | Unclassified | $185.7M | $1.4B |
| 5 | Insight Chicago INC | Health Care | $150.6M | $104.8M |
| 6 | Sunset Hills Association | Unclassified | $141.8M | $50.1M |
| 7 | McLaren Medical Group | Health Care | $120.1M | $99.2M |
| 8 | Kettering University | Education | $97.3M | $279.1M |
| 9 | Promedica Coldwater Regional Hospital | Health Care | $86.0M | $41.7M |
| 10 | Food Bank of Eastern Michigan INC | Food, Agriculture & Nutrition | $76.7M | $39.3M |
| 11 | Genesee Education Consultant Services INC | Education | $73.9M | $14.1M |
| 12 | Flint and Genesee Chamber Foundation | Unclassified | $58.9M | $142.0M |
| 13 | Community Foundation of Greater Flint | Philanthropy, Voluntarism & Grantmaking | $58.6M | $313.9M |
| 14 | Mott Childrens Health Center | Health Care | $54.3M | $559.9M |
| 15 | Ruth Mott Foundation | Education | $45.8M | $271.7M |
| 16 | Hurley Clinics | Health Care | $40.0M | $13.2M |
| 17 | Goodwill Industries of Mid-michigan INC | Employment | $36.7M | $24.1M |
| 18 | Hamilton Community Health Network INC | Health Care | $33.4M | $30.6M |
| 19 | McLaren Health Plan Community | Health Care | $31.5M | $45.8M |
| 20 | Michigan Community Services INC | Human Services | $25.4M | $11.3M |
| 21 | Valley Area Agency on Aging | Unclassified | $24.2M | $19.8M |
| 22 | Anna Paulina Foundation | Unclassified | $23.2M | $33.0M |
| 23 | Sovita Credit Union | Unclassified | $21.3M | $529.4M |
| 24 | Flint Institute of Music | Arts, Culture & Humanities | $20.1M | $39.0M |
| 25 | Ennis Center for Children INC | Human Services | $18.7M | $12.1M |
| 26 | Hwd on Second INC | Community Improvement & Capacity Building | $17.5M | $26.2M |
| 27 | Flint Kids Learn | Education | $15.5M | $10.9M |
| 28 | Flint Cultural Center Corporation INC | Arts, Culture & Humanities | $14.2M | $64.6M |
| 29 | Flint Cultural Center Foundation | Arts, Culture & Humanities | $12.3M | $5.6M |
| 30 | Isabel Foundation | Unclassified | $12.0M | $88.3M |
| 31 | Whaley Memorial Foundation | Human Services | $11.8M | $17.2M |
| 32 | Flint Institute of Arts | Arts, Culture & Humanities | $11.7M | $65.0M |
| 33 | Greater Flint Health Coalition INC | Health Care | $10.8M | $6.8M |
| 34 | Young Mens Christian Association of Flint | Unclassified | $10.7M | $40.8M |
| 35 | Flint Odyssey House INC | Mental Health & Crisis Intervention | $10.6M | $4.8M |
| 36 | Genesys Hurley Cancer Institute | Health Care | $10.1M | $17.8M |
| 37 | United Way of Genesee County | Philanthropy, Voluntarism & Grantmaking | $9.9M | $9.6M |
| 38 | New Paths INC | Crime & Legal-Related | $9.0M | $7.0M |
| 39 | Catholic Charities of Shiawassee & Genesee Counties | Unclassified | $9.0M | $11.9M |
| 40 | Communities First INC | Housing & Shelter | $8.5M | $33.7M |
| 41 | Foundation for the Uptown Reinvestment Corporation | Philanthropy, Voluntarism & Grantmaking | $8.2M | $7.0M |
| 42 | McLaren Flint Foundation | Health Care | $8.2M | $66.0M |
| 43 | Flint Institute of Science & History | Unclassified | $8.2M | $9.5M |
| 44 | Flint Center for Educational Excellence | Education | $7.8M | $3.3M |
| 45 | Uptown Reinvestment Corporation INC | Community Improvement & Capacity Building | $7.5M | $83.4M |
| 46 | Metro Community Development INC | Community Improvement & Capacity Building | $7.2M | $18.4M |
| 47 | McFarlan Charitable Corporation | Unclassified | $7.1M | $31.4M |
| 48 | Genesee Health Plan | Health Care | $6.8M | $8.0M |
| 49 | Genesee Landlords Association | Unclassified | $6.3M | $1.3M |
| 50 | Legal Services of Eastern Michigan | Crime & Legal-Related | $5.8M | $2.5M |
| 51 | Foundation for Mott Community College | Education | $5.2M | $13.1M |
| 52 | Hurley Foundation | Civil Rights, Social Action & Advocacy | $5.2M | $14.6M |
| 53 | International Union United Auto Aerospace & Agricultural Workers | Unclassified | $5.1M | $3.6M |
| 54 | Michigan State Education Network | Education | $5.0M | $23.6M |
| 55 | Chinmaya Education Foundation INC | Education | $5.0M | $3.8M |
| 56 | Center for Land Reform INC | Environment | $4.9M | $4.8M |
| 57 | Greater Flint Mental Health Facilities INC | Unclassified | $4.6M | $34.1M |
| 58 | Flint and Genesee Group | Community Improvement & Capacity Building | $4.5M | $3.2M |
| 59 | Carriage Town Ministries | Arts, Culture & Humanities | $3.6M | $9.2M |
| 60 | Crim Fitness Foundation INC | Unclassified | $3.5M | $3.7M |
| 61 | Habitat for Humanity International INC | Unclassified | $3.5M | $7.9M |
| 62 | International Brotherhood of Electrical Workers | Unclassified | $3.3M | $4.7M |
| 63 | Hurley Health Services | Health Care | $3.2M | $15.9M |
| 64 | YWCA of Greater Flint | Human Services | $3.1M | $5.0M |
| 65 | Charles Stewart Harding Foundation | Unclassified | $3.0M | $16.4M |
| 66 | Paiges Supervised Community Living INC | Human Services | $2.9M | $289K |
| 67 | Bruin Club of Genesee County | Education | $2.8M | $1.4M |
| 68 | International Union United Auto Aerospace & Agricultural Workers | Unclassified | $2.8M | $1.4M |
| 69 | Genesee Christian Day Care Service | Unclassified | $2.8M | $3.0M |
| 70 | St. Luke N E W Life Center INC | Unclassified | $2.6M | $2.4M |
| 71 | Sylvester Broome Empowerment Village | Community Improvement & Capacity Building | $2.5M | $2.5M |
| 72 | Newton Services Foundation INC | Education | $2.5M | $3.3M |
| 73 | Shelter of Flint INC | Housing & Shelter | $2.4M | $5.9M |
| 74 | International Brotherhood Teamsters Chauffrs | Unclassified | $2.4M | $292K |
| 75 | North Flint Reinvestment Corporation | Human Services | $2.4M | $631K |
| 76 | Boys and Girls Club of Greater Flint | Youth Development | $2.3M | $3.1M |
| 77 | Foundation for the Flint Cultural Center | Arts, Culture & Humanities | $2.2M | $51.7M |
| 78 | Disability Network | Civil Rights, Social Action & Advocacy | $2.2M | $629K |
| 79 | Family Service Agency of Mid Michigan | Human Services | $2.1M | $3.0M |
| 80 | Reach Resource Services | Human Services | $2.1M | $1.0M |
| 81 | Flint Golf Club | Unclassified | $2.1M | $1.5M |
| 82 | Its Just Money | Environment | $2.1M | $1.3M |
| 83 | Flint Electrical Joint Apprenticeship Training Committee | Education | $1.8M | $2.2M |
| 84 | McFarlan Kearsley Residence LLC | Housing & Shelter | $1.8M | $2.0M |
| 85 | Flint Fresh | Food, Agriculture & Nutrition | $1.7M | $1.7M |
| 86 | Registered Nurses and Registered Pharmacists of Hurley Medical | Unclassified | $1.6M | $5.4M |
| 87 | International Union United Auto Aerospace & Agricultural Workers | Unclassified | $1.5M | $2.5M |
| 88 | Grace Emmanuel Baptist Church | Unclassified | $1.5M | $2.7M |
| 89 | Sunshine Family Cares INC | Human Services | $1.5M | $533K |
| 90 | Genesee Area Focus Fund INC | Unclassified | $1.4M | $708K |
| 91 | Ferris Wheel Innovation Center | Education | $1.4M | $571K |
| 92 | Laborers International Union of North America | Unclassified | $1.4M | $3.1M |
| 93 | Greater Flint Arts Council | Unclassified | $1.3M | $1.9M |
| 94 | Saginaw Odyssey House | Mental Health & Crisis Intervention | $1.3M | $1.0M |
| 95 | Foundation for Flint | Philanthropy, Voluntarism & Grantmaking | $1.3M | $4.6M |
| 96 | Flint Childrens Museum | Arts, Culture & Humanities | $1.2M | $2.8M |
| 97 | Friends of Berston | Human Services | $1.1M | $21.5M |
| 98 | Big Brothers Big Sisters of Flint and Genesee County | Youth Development | $1.1M | $1.4M |
| 99 | Insight Research Institute | Medical Research | $1.1M | $348K |
| 100 | Greater Beecher Business District Association | Community Improvement & Capacity Building | $1.0M | $301K |