| 1 | Puffin Bay Foundation | Philanthropy, Voluntarism & Grantmaking | $784.2M | $679.0M |
| 2 | University of New England | Education | $394.8M | $788.8M |
| 3 | Kahle-austin Family Foundation | Philanthropy, Voluntarism & Grantmaking | $181.1M | $118.7M |
| 4 | Kahle-austin Foundation | Philanthropy, Voluntarism & Grantmaking | $129.4M | $161.8M |
| 5 | Permanent Archive Fund | Education | $51.0M | $36.1M |
| 6 | Archive Sustaining Foundation | Education | $40.5M | $31.5M |
| 7 | St. Andre Health Care Facility | Unclassified | $12.4M | $5.7M |
| 8 | Star Library Foundation | Education | $9.8M | $9.4M |
| 9 | Open Library of Richmond INC | Education | $9.7M | $27.6M |
| 10 | Better World Libraries | Arts, Culture & Humanities | $7.9M | $25.3M |
| 11 | Southern Maine Agency on Aging | Human Services | $7.9M | $7.2M |
| 12 | Barbara Cassidy Foundation | Philanthropy, Voluntarism & Grantmaking | $5.0M | $4.2M |
| 13 | McArthur Library Association | Education | $4.3M | $7.5M |
| 14 | Southern Maine Finance Agency | Community Improvement & Capacity Building | $1.4M | $7.9M |
| 15 | Seeds of Hope Neighborhood Center | Religion-Related | $1.0M | $1.2M |
| 16 | Amvets | Unclassified | $1.0M | $146K |
| 17 | Abenakee Club | Unclassified | $996K | $1.4M |
| 18 | McArthur Home for Aged People Assoc | Unclassified | $805K | $5.8M |
| 19 | Southern Maine Affordable Housing | Housing & Shelter | $754K | $4.6M |
| 20 | Thatcher Brook Center | Human Services | $713K | $235K |
| 21 | Fraternal Order of Eagles | Unclassified | $653K | $279K |
| 22 | The Iusn Foundation | Education | $625K | $197K |
| 23 | United Ostomy Associations of America INC | Medical Research | $614K | $1.3M |
| 24 | Heart of Biddeford | Community Improvement & Capacity Building | $608K | $178K |
| 25 | York County Arena Association | Arts, Culture & Humanities | $564K | $309K |
| 26 | City Theater Associates INC 205 Main St. | Arts, Culture & Humanities | $552K | $451K |
| 27 | Youth Full Maine | Food, Agriculture & Nutrition | $484K | $33K |
| 28 | Biddeford Youth Hockey Association | Recreation & Sports | $433K | $128K |
| 29 | Biddeford Food Pantry | Human Services | $406K | $1.2M |
| 30 | Greenwood Cemetery Association | Unclassified | $332K | $1.8M |
| 31 | St. Louis Alumni Association INC | Education | $254K | $1.1M |
| 32 | Apex Youth Connection | Youth Development | $242K | $907K |
| 33 | Biddeford Saco Chamber of Commerce INC | Unclassified | $163K | $52K |
| 34 | A Running Passion | Philanthropy, Voluntarism & Grantmaking | $154K | $72K |
| 35 | Maine Lighthouse Trust | Philanthropy, Voluntarism & Grantmaking | $149K | $19K |
| 36 | Little League Baseball INC | Unclassified | $113K | $141K |
| 37 | Maine Independent Colleges Association | Education | $111K | $57K |
| 38 | Biddeford Public School Education Foundation | Youth Development | $109K | $103K |
| 39 | Vision Partners | Religion-Related | $103K | $25K |
| 40 | Bon Apetit-community Meal Program | Food, Agriculture & Nutrition | $102K | $144K |
| 41 | Library Futures Foundation | Public & Societal Benefit | $100K | $66K |
| 42 | Vet to Vet Maine | Human Services | $97K | $53K |
| 43 | La Kermesse Franco-americaine de Biddeford INC | Arts, Culture & Humanities | $75K | $40K |
| 44 | Northeast Osteopathic Medical Education Network | Medical Research | $66K | $14K |
| 45 | Subcircle INC | Arts, Culture & Humanities | $65K | $12K |
| 46 | Outliers Robotics | Youth Development | $60K | $35K |
| 47 | Olps-us | Human Services | $55K | $11K |
| 48 | St. Demetrios Hellenic Orthodox Cemetary Association | Mutual & Membership Benefit | $53K | $355K |
| 49 | Ever After Mustang Rescue Training and Educational Center | Animal-Related | $20K | $253K |
| 50 | Earth Ocean Food Systems Ethos INC | Animal-Related | $8K | $3K |
| 51 | Maine Association of Area Agencies on Aging | Human Services | $50 | $5K |
| 52 | Michael William Langevin Scholarship Fund | Education | $1 | $19K |
| 53 | Maine Way INC | Housing & Shelter | $0 | $0 |
| 54 | New Life Christian Fellowship | Religion-Related | $0 | $0 |
| 55 | Little House of Prayer INC | Religion-Related | $0 | $0 |
| 56 | Maine Professional Drivers Association INC | Education | $0 | $0 |
| 57 | Biddeford Athletic Association | Recreation & Sports | $0 | $0 |
| 58 | Amvets | Unclassified | $0 | $0 |
| 59 | Amvets | Unclassified | $0 | $0 |
| 60 | Youth Education in Sports Foundation | Youth Development | $0 | $0 |
| 61 | Tricity Community Chorus INC | Arts, Culture & Humanities | $0 | $0 |
| 62 | Ancient Free & Ancient Masons of Maine | Unclassified | $0 | $0 |
| 63 | American Legion Post 26 Tighe- Beauddin-farley | Unclassified | $0 | $0 |
| 64 | Biddeford Pool Volunteer Fire Department INC | Unclassified | $0 | $0 |
| 65 | Biddeford Youth Lacrosse | Recreation & Sports | $0 | $0 |
| 66 | Peace Corps Friends of Dr Congo | Social Science | $0 | $0 |
| 67 | Amvets | Unclassified | $0 | $0 |
| 68 | Univ of New England Coll of Osteopathic Medicine Alumni Assn. | Education | $0 | $0 |
| 69 | National Rural Letter Carriers Association | Unclassified | $0 | $0 |
| 70 | Nina Mary Browne Scholarship Fund | Education | $0 | $0 |
| 71 | Sigma Sigma Phi | Unclassified | $0 | $0 |
| 72 | Alumni Band | Arts, Culture & Humanities | $0 | $0 |
| 73 | Biddeford Mills Museum | Arts, Culture & Humanities | $0 | $0 |
| 74 | Operation Cross Check | Human Services | $0 | $0 |
| 75 | Biddeford Community Recovery Center | Mental Health & Crisis Intervention | $0 | $0 |
| 76 | St. Demetrios Endowment Foundation | Religion-Related | $0 | $0 |
| 77 | Blandings Park Wildlife Sanctuary | Environment | $0 | $0 |
| 78 | Vietnam Veterans of America Chapter 1044 | Unclassified | $0 | $0 |
| 79 | Southern Maine Boxing Club | Recreation & Sports | $0 | $0 |
| 80 | Skate to Relate | Youth Development | $0 | $0 |
| 81 | Maine Music Collective | Arts, Culture & Humanities | $0 | $0 |
| 82 | Gracepoint Church | Religion-Related | $0 | $0 |
| 83 | Fraternal Order of Police | Unclassified | $0 | $0 |
| 84 | Biddeford Historical Society | Arts, Culture & Humanities | $0 | $0 |
| 85 | Dudziaks Parent Association Booster Club | Recreation & Sports | $0 | $0 |
| 86 | Biddeford Zhongzhou Christian Ministries | Religion-Related | $0 | $0 |
| 87 | Friends of Pack 311 Saco | Youth Development | $0 | $0 |
| 88 | Biddeford Cultural and Heritage Center | Arts, Culture & Humanities | $0 | $0 |
| 89 | Harvest Foundation | Human Services | $0 | $0 |
| 90 | Thomas Behen Fund INC | Youth Development | $0 | $0 |
| 91 | Friends of West Brook Skating Rink | Recreation & Sports | $0 | $0 |
| 92 | In-a-pinch Non-food Pantry | Human Services | $0 | $0 |
| 93 | Biddeford Project Sunrise | Education | $0 | $0 |
| 94 | Hills Beach Community Center INC | Community Improvement & Capacity Building | $0 | $0 |
| 95 | Biddeford Wrestling Foundation | Recreation & Sports | $0 | $0 |
| 96 | Protect Maines Fishing Heritage | Employment | $0 | $0 |
| 97 | Save Our Libraries Institute | Education | $0 | $0 |
| 98 | Hills Beach Association | Public & Societal Benefit | $0 | $0 |
| 99 | Iraqi Community Center in Maine | Community Improvement & Capacity Building | $0 | $0 |
| 100 | Thomas Behen Casting Camp INC | Recreation & Sports | $0 | $0 |