| 1 | Charles County Nursing Home INC | Health Care | $15.7M | $7.4M |
| 2 | Spring Dell Center INC | Human Services | $13.7M | $19.3M |
| 3 | University of Maryland Charles Regional Health INC | Health Care | $10.1M | $26.0M |
| 4 | Lifestyles of Maryland Foundation INC | Human Services | $5.8M | $9.7M |
| 5 | Center for Children INC | Unclassified | $5.4M | $2.5M |
| 6 | Cerenity INC | Human Services | $3.5M | $1.3M |
| 7 | American Legion Harry White Wilmer Post 82 | Unclassified | $3.1M | $978K |
| 8 | George R Jr and Donna M Wilsonfamily Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.1M | $1.9M |
| 9 | Family of Care Real Estate Holding Co INC | Human Services | $1.9M | $17.8M |
| 10 | Southern Maryland Youth Home | Youth Development | $1.7M | $396K |
| 11 | Impacto Ministry INC | Religion-Related | $1.5M | $1.1M |
| 12 | Project Healing Waters Fly Fishing INC | Health Care | $1.2M | $1.2M |
| 13 | Charles County Fair INC | Recreation & Sports | $1.1M | $2.3M |
| 14 | Charles County Freedom Landing INC | Mental Health & Crisis Intervention | $1.1M | $717K |
| 15 | Charles Regional Medical Center Foundation INC | Unclassified | $1.1M | $6.5M |
| 16 | Hawthorne Country Club of Charles County Maryland INC | Unclassified | $983K | $162K |
| 17 | Charles County Rescue Squad INC | Health Care | $724K | $1.3M |
| 18 | Southern Maryland Athletic Alliance | Recreation & Sports | $640K | $290K |
| 19 | Charles County Volunteer Firemens Association INC | Public Safety, Disaster Preparedness & Relief | $562K | $416K |
| 20 | Dentsville Volunteer EMS and Auxillary INC | Health Care | $517K | $2.7M |
| 21 | Through Piscataway Eyes Tpe INC | Human Services | $451K | $493K |
| 22 | Charles County Scholarship Fund INC | Unclassified | $424K | $986K |
| 23 | Port Tobacco Players INC | Arts, Culture & Humanities | $408K | $1.1M |
| 24 | Education Association of Charles County INC | Unclassified | $344K | $738K |
| 25 | Charles County Chamber of Commerce INC | Community Improvement & Capacity Building | $297K | $169K |
| 26 | Fr Michaels Mission INC | Crime & Legal-Related | $289K | $72 |
| 27 | Fc Charles 1658 | Recreation & Sports | $277K | $86K |
| 28 | McDonough Charity School | Unclassified | $271K | $1.1M |
| 29 | Fraternal Order of Police | Unclassified | $258K | $674K |
| 30 | Charles County Arts Alliance INC | Arts, Culture & Humanities | $251K | $77K |
| 31 | The United Way of Southern Maryland INC | Philanthropy, Voluntarism & Grantmaking | $223K | $366K |
| 32 | Charlotte Hall School Board of Trustees | Unclassified | $171K | $482K |
| 33 | Pure Play Every Day INC | Human Services | $166K | $42K |
| 34 | Annapolis Cove Property Owners Assn INC | Unclassified | $163K | $447K |
| 35 | Charles County Youth League | Recreation & Sports | $151K | $27K |
| 36 | Ncac | Arts, Culture & Humanities | $130K | $74K |
| 37 | Maryland Veterans Memorial Museum INC | Arts, Culture & Humanities | $129K | $3.3M |
| 38 | La Plata Youth Soccer Association INC | Recreation & Sports | $123K | $173K |
| 39 | Charles County Nursing and Rehabilitation Center Foundation | Housing & Shelter | $105K | $631K |
| 40 | Point of Change Jail and Street Ministry INC | Religion-Related | $92K | $22K |
| 41 | Sasaya Family Foundation | Philanthropy, Voluntarism & Grantmaking | $58K | $46K |
| 42 | Thimble Collectors International | Unclassified | $56K | $128K |
| 43 | Little Beans Orphan Ark Rescue Corp. | Animal-Related | $51K | $1K |
| 44 | Mobile Steaam Solutions INC | Youth Development | $43K | $1K |
| 45 | The Bel Alton High School Alumni Assoc Community Development Corp. | Education | $14K | $26K |
| 46 | John Gray Family Foundation | Human Services | $13K | $3K |
| 47 | Foundation to Defend the First Amendment | Civil Rights, Social Action & Advocacy | $10K | $36K |
| 48 | Serendipityanimalrescueinc | Animal-Related | $6K | $1 |
| 49 | Live Life Grand Foundation INC | Unclassified | $2K | $2K |
| 50 | L O a a D INC | Education | $420 | $1 |
| 51 | Arunbhai Foundation INC | Medical Research | $2 | $1K |
| 52 | Pvfsr Foundation INC | Unclassified | $1 | $185K |
| 53 | La Plata Church of Christ | Religion-Related | $0 | $0 |
| 54 | La Plata African Methodist Episcopal Church INC | Unclassified | $0 | $0 |
| 55 | Christ Tabernacle Church Ministries INC | Unclassified | $0 | $0 |
| 56 | Theta Nu XI Multicultural Sorority INC | Education | $0 | $0 |
| 57 | Blue Knights Motorcycle Club | Unclassified | $0 | $0 |
| 58 | Eastern Association of Intercollegiate Football Official | Unclassified | $0 | $0 |
| 59 | Historical Society of Charles County INC | Unclassified | $0 | $0 |
| 60 | Grace Lutheran Church | Unclassified | $0 | $0 |
| 61 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 62 | Oxon Hill Bicycle & Trail Club INC | Unclassified | $0 | $0 |
| 63 | Knights of Columbus | Unclassified | $0 | $0 |
| 64 | Restorers of Mount Carmel in Maryland INC | Arts, Culture & Humanities | $0 | $0 |
| 65 | La Plata Community Foundation INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 66 | American Inns of Court Foundation | Unclassified | $0 | $0 |
| 67 | Power of One Life Example Alliance INC | Education | $0 | $0 |
| 68 | Charles County Disaster Relief Fund | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 69 | Southern Maryland Carousel Group INC | Arts, Culture & Humanities | $0 | $0 |
| 70 | Start Strong INC | Human Services | $0 | $0 |
| 71 | De Profundis INC | Religion-Related | $0 | $0 |
| 72 | Evergreen How to Succeed Philanthropic Foundation | Education | $0 | $0 |
| 73 | Citizens for the Charles County Public Library | Education | $0 | $0 |
| 74 | Encounter Community Church | Religion-Related | $0 | $0 |
| 75 | Animal Rescue Foundation | Animal-Related | $0 | $0 |
| 76 | Operation Safe Shelter INC | Human Services | $0 | $0 |
| 77 | Christ Foundation Church INC | Religion-Related | $0 | $0 |
| 78 | Reachmore Church of God in Christ INC | Religion-Related | $0 | $0 |
| 79 | Somd Tkd Booster Club | Recreation & Sports | $0 | $0 |
| 80 | Prince Georges County Police Athletic League Incorporation | Youth Development | $0 | $0 |
| 81 | Archbishop Neale School | Unclassified | $0 | $0 |
| 82 | First Baptist Church of la Plata | Unclassified | $0 | $0 |
| 83 | Potomac Baptist Association | Unclassified | $0 | $0 |
| 84 | Improved Benevolent & Protective Order of Elks of the World | Unclassified | $0 | $0 |
| 85 | Jobs Daughters International | Unclassified | $0 | $0 |
| 86 | Rotary International | Unclassified | $0 | $0 |
| 87 | Calvary Grace Assembly of God | Unclassified | $0 | $0 |
| 88 | Federated Garden Clubs of Maryland INC | Environment | $0 | $0 |
| 89 | American Legion Auxiliary | Unclassified | $0 | $0 |
| 90 | Clarks Run Citizens Association INC | Unclassified | $0 | $0 |
| 91 | Charles County Literacy Council INC | Unclassified | $0 | $0 |
| 92 | Bethel Baptist Church INC | Unclassified | $0 | $0 |
| 93 | Patuxent Dental Society INC | Unclassified | $0 | $0 |
| 94 | National Society of the Sons of the American Revolution | Unclassified | $0 | $0 |
| 95 | Southern Maryland Woodcarvers | Unclassified | $0 | $0 |
| 96 | Prince Georges County Police and Public Safety Foundation INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 97 | Masjid Abdul-moghni INC | Religion-Related | $0 | $0 |
| 98 | Charles County Amateur Radio Club INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 99 | Zoe Outreach Ministries International INC | Religion-Related | $0 | $0 |
| 100 | Muslim Family Foundation INC | Religion-Related | $0 | $0 |