| 1 | Hood College of Frederick Md | Education | $846.5M | $318.8M |
| 2 | Frederick Health Hospital INC | Health Care | $457.2M | $665.6M |
| 3 | Asbury Atlantic INC | Human Services | $310.9M | $566.1M |
| 4 | Aircraft Owners & Pilots Asso | Unclassified | $141.1M | $148.2M |
| 5 | Frederick Health Medical Group LLC | Health Care | $122.9M | $36.8M |
| 6 | Albright Care Services | Human Services | $110.2M | $91.2M |
| 7 | Service Coordination INC | Unclassified | $90.9M | $23.4M |
| 8 | Way Station INC | Human Services | $59.9M | $49.6M |
| 9 | Aopa Foundation | Public Safety, Disaster Preparedness & Relief | $59.6M | $61.6M |
| 10 | Community Foundation of Frederick County Maryland Incorporated | Philanthropy, Voluntarism & Grantmaking | $55.4M | $193.3M |
| 11 | The Village at Rockville INC | Human Services | $45.3M | $144.3M |
| 12 | Village at Orchard Ridge INC | Housing & Shelter | $32.0M | $145.7M |
| 13 | Asbury Communities INC | Health Care | $29.7M | $22.0M |
| 14 | American Association for Laboratory Accreditation | Science & Technology | $28.4M | $22.1M |
| 15 | Young Mens Christian Assoc INC | Human Services | $25.6M | $52.0M |
| 16 | Aaalac International INC | Animal-Related | $25.1M | $17.8M |
| 17 | Asbury Foundation INC | Philanthropy, Voluntarism & Grantmaking | $23.1M | $60.9M |
| 18 | Arc of Frederick County INC | Unclassified | $16.4M | $24.9M |
| 19 | Word Among US INC | Unclassified | $15.3M | $23.6M |
| 20 | Allemall Foundation INC | Philanthropy, Voluntarism & Grantmaking | $14.2M | $32.8M |
| 21 | Asbury INC | Human Services | $12.2M | $1.2M |
| 22 | Ausherman Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $10.7M | $23.1M |
| 23 | Asbury Living INC | Housing & Shelter | $9.5M | $29.0M |
| 24 | Delaplaine Foundation INC | Philanthropy, Voluntarism & Grantmaking | $9.4M | $44.1M |
| 25 | National Lutheran INC | Housing & Shelter | $8.8M | $6.9M |
| 26 | Mental Health Assoc of Frederck Cty | Mental Health & Crisis Intervention | $8.5M | $5.2M |
| 27 | Frederick Innovative Technology Center INC | Community Improvement & Capacity Building | $7.8M | $11.0M |
| 28 | Frederick Rescue Mission INC | Housing & Shelter | $7.4M | $7.0M |
| 29 | The Legacy at North August INC | Human Services | $7.0M | $24.0M |
| 30 | Home for the Aged of Frederick City | Unclassified | $6.1M | $32.0M |
| 31 | Nassco INC | Unclassified | $5.9M | $4.1M |
| 32 | National Auto Auction Association INC | Unclassified | $5.9M | $16.7M |
| 33 | Richard B Shorten Family Foundation INC | Public & Societal Benefit | $5.8M | $2.9M |
| 34 | The Great Frederick Fair INC | Unclassified | $5.7M | $2.0M |
| 35 | Frederick Classical Charter School INC | Education | $5.5M | $5.5M |
| 36 | Workers United | Unclassified | $5.2M | $10.6M |
| 37 | The Delaplaine Arts Center INC | Arts, Culture & Humanities | $4.9M | $13.4M |
| 38 | Heartly House INC | Human Services | $4.5M | $2.7M |
| 39 | All Hazards Consortium INC | Human Services | $4.1M | $1.1M |
| 40 | Loats Foundation INC | Unclassified | $3.8M | $4.5M |
| 41 | Life and Discovery INC | Education | $3.8M | $4.8M |
| 42 | American Lumber Standard Committee Incorporated | Environment | $3.7M | $6.4M |
| 43 | Habitat for Humanity International INC | Unclassified | $3.7M | $5.1M |
| 44 | Scott Key Center INC | Employment | $3.6M | $1.5M |
| 45 | Tourism Council of Frederick County INC | Unclassified | $3.4M | $4.3M |
| 46 | Partners in Evangelism INC | Human Services | $3.3M | $1.5M |
| 47 | Beyond Shelter Frederick INC | Religion-Related | $3.3M | $4.1M |
| 48 | United Way of Frederick County Incorporated | Philanthropy, Voluntarism & Grantmaking | $3.2M | $1.2M |
| 49 | The Ranch INC | Human Services | $3.2M | $2.8M |
| 50 | Ed Whittington Charitable Tr | Unclassified | $3.1M | $4.3M |
| 51 | Dr Henry P and M Page Durkee Laughlin Foundation INC | Unclassified | $3.0M | $4.4M |
| 52 | Airborne Public Safety Association Incorporated | Crime & Legal-Related | $2.9M | $4.3M |
| 53 | Frederick Community College Foundation INC | Unclassified | $2.9M | $23.4M |
| 54 | Frederick Health Hospice INC | Human Services | $2.9M | $16.5M |
| 55 | The Ausherman Family Trust | Philanthropy, Voluntarism & Grantmaking | $2.7M | $4.8M |
| 56 | Weinberg Center for the Arts INC | Arts, Culture & Humanities | $2.5M | $1.8M |
| 57 | 1 Chippewa 19 Improved Order of Redmen INC | Recreation & Sports | $2.5M | $750K |
| 58 | Downtown Frederick Partnership INC | Community Improvement & Capacity Building | $2.4M | $1.3M |
| 59 | National Museum for Civil War Medicine INC | Arts, Culture & Humanities | $2.3M | $16.3M |
| 60 | A2la Workplace Training INC | Philanthropy, Voluntarism & Grantmaking | $2.2M | $1.8M |
| 61 | Monocacy Montessori Community INC | Unclassified | $2.1M | $24.8M |
| 62 | American Legion | Unclassified | $2.0M | $913K |
| 63 | The Banner School INC | Unclassified | $2.0M | $503K |
| 64 | Mount Olivet Cemetery | Unclassified | $2.0M | $6.1M |
| 65 | C Burr Artz Library | Unclassified | $2.0M | $6.5M |
| 66 | Interfaith Housing Alliance INC | Housing & Shelter | $1.9M | $3.1M |
| 67 | Asia Partners INC | Religion-Related | $1.8M | $2.3M |
| 68 | F C Frederick INC | Recreation & Sports | $1.8M | $4.7M |
| 69 | Frederick Health INC | Health Care | $1.8M | $334.4M |
| 70 | Benevolent & Protective Order of Elks of the USA | Unclassified | $1.7M | $133K |
| 71 | American College of Real Estate Lawyers | Education | $1.7M | $1.9M |
| 72 | Frederick Arts Council INC | Arts, Culture & Humanities | $1.7M | $644K |
| 73 | Naaa Warren Young Sr Scholastic Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.6M | $2.9M |
| 74 | William E Cross Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.5M | $7.6M |
| 75 | National Society of Professional Surveyors INC | Unclassified | $1.4M | $1.1M |
| 76 | National Lutheran Home for the Aged Incorporated | Housing & Shelter | $1.4M | $86.2M |
| 77 | Independent Hose Company-1 | Unclassified | $1.4M | $3.5M |
| 78 | Daybreak Adult Day Services INC | Human Services | $1.3M | $1.3M |
| 79 | United Steam Fire Engine Co-3 | Public Safety, Disaster Preparedness & Relief | $1.3M | $3.5M |
| 80 | Chamber of Commerce of Frederick County INC | Unclassified | $1.2M | $944K |
| 81 | Mid-atlantic Regional Health Fund a | Unclassified | $1.2M | $2.7M |
| 82 | Second Chances Garage | Human Services | $1.2M | $393K |
| 83 | G Frank Thomas Foundation INC | Unclassified | $1.2M | $3.6M |
| 84 | Boys and Girls Club of Frederick County INC | Youth Development | $1.2M | $851K |
| 85 | Woods Homeowners Association INC | Housing & Shelter | $1.1M | $1.8M |
| 86 | International Association of Fire Fighters | Unclassified | $1.1M | $713K |
| 87 | Amvets | Unclassified | $1.1M | $680K |
| 88 | Diesel Technology Forum INC | Community Improvement & Capacity Building | $1.1M | $752K |
| 89 | Historical Society of Frederick County INC | Arts, Culture & Humanities | $1.0M | $3.4M |
| 90 | Maryland Deaf Community Center - Frederick - INC | Arts, Culture & Humanities | $982K | $3.1M |
| 91 | Student Homelessness Initiative Partnership of Frederick County in | Human Services | $973K | $547K |
| 92 | Maryland Ensemble Theatre INC | Education | $960K | $1.1M |
| 93 | The Monocacy Foundation INC | Human Services | $908K | $1.2M |
| 94 | United Methodist Association of Health and Welfare Ministries | Religion-Related | $907K | $1.4M |
| 95 | Centro Hispano de Frederick INC | Human Services | $876K | $739K |
| 96 | Frederick County Humane Society INC | Animal-Related | $863K | $1.7M |
| 97 | Owls Club No 4002 Incorporated | Unclassified | $843K | $136K |
| 98 | Transform Mid-atlantic INC | Education | $814K | $1.7M |
| 99 | Frederick Lodge No 371 Loyal Order of Moose | Unclassified | $803K | $1.1M |
| 100 | Warrior Run Manor INC | Unclassified | $783K | $1.7M |