| 1 | St. Luke Homes & Services INC | Unclassified | $11.1M | $7.6M |
| 2 | Northwest Iowa Mental Health Center | Mental Health & Crisis Intervention | $9.5M | $8.3M |
| 3 | Community Housing Initiatives INC | Housing & Shelter | $8.6M | $53.6M |
| 4 | Spencer Regional Healthcare Foundation | Health Care | $8.1M | $26.7M |
| 5 | Eastwood of Ames INC | Housing & Shelter | $3.4M | $20.9M |
| 6 | Young Mens Christian Association of Spencer Iowa | Human Services | $2.9M | $3.7M |
| 7 | Spencer Industries Foundation | Unclassified | $2.7M | $1.9M |
| 8 | Regional Transit Authority Art | Public & Societal Benefit | $2.6M | $5.1M |
| 9 | Center Against Abuse Sexual Assault Caasa | Unclassified | $1.3M | $1.5M |
| 10 | Iowa Lakes Corridor Development Corporation | Community Improvement & Capacity Building | $638K | $3.1M |
| 11 | Spencer Chamber of Commerce Foundation | Public & Societal Benefit | $618K | $372K |
| 12 | Shayla Bee Fund INC | Philanthropy, Voluntarism & Grantmaking | $570K | $1.4M |
| 13 | Spencer Community School Foundation | Education | $570K | $2.2M |
| 14 | Birthright of Spencer Iowa | Civil Rights, Social Action & Advocacy | $512K | $518K |
| 15 | Spencer Main Street Company | Community Improvement & Capacity Building | $376K | $290K |
| 16 | People for Pets | Animal-Related | $343K | $542K |
| 17 | N W Iowa Youth Soccer Alliance | Recreation & Sports | $331K | $837K |
| 18 | Spencer Chamber of Commerce | Unclassified | $303K | $255K |
| 19 | Love Takes Root | Human Services | $298K | $331K |
| 20 | Northwest Iowa Housing Trust Fund INC | Housing & Shelter | $288K | $2.0M |
| 21 | United Way of Spencer | Philanthropy, Voluntarism & Grantmaking | $261K | $1.3M |
| 22 | Clay County Fair Association | Unclassified | $250K | $7.7M |
| 23 | Spencer Community Theatre INC | Arts, Culture & Humanities | $234K | $1.6M |
| 24 | Clay County Council on Aging | Human Services | $227K | $306K |
| 25 | Fresh Start Market and Boutique INC | Human Services | $221K | $76K |
| 26 | Arts on Grand | Unclassified | $198K | $583K |
| 27 | Kiwanis International INC | Unclassified | $176K | $396K |
| 28 | Adolph and Esther Vestergaard Memorial Scholarship Fund Trust | Unclassified | $168K | $780K |
| 29 | Atlas of Spencer | Human Services | $164K | $149K |
| 30 | Public Benefit Holding Corporation of Spencer Iowa | Unclassified | $162K | $2.3M |
| 31 | Grand Avenue Community Outreach | Human Services | $138K | $699K |
| 32 | Maple Valley Housing INC | Unclassified | $128K | $153K |
| 33 | Clay County Pork Producers | Unclassified | $125K | $82K |
| 34 | Spencer Little League Assn. | Unclassified | $121K | $168K |
| 35 | Kiwanis International INC | Unclassified | $120K | $135K |
| 36 | Masonic Temple Association INC | Religion-Related | $104K | $226K |
| 37 | Spencer Tailtwister Booster Club | Education | $98K | $57K |
| 38 | Clay County Heritage | Unclassified | $91K | $2.0M |
| 39 | Iowa Farm Bureau Federation | Unclassified | $90K | $1.2M |
| 40 | Iowa Great Lakes Fishing Club | Animal-Related | $79K | $35K |
| 41 | Association of Regional Water Organizations | Community Improvement & Capacity Building | $72K | $236K |
| 42 | Community Housing Access & Resource Team | Housing & Shelter | $60K | $56K |
| 43 | Rotary Club of Spencer Iowa | Community Improvement & Capacity Building | $57K | $74K |
| 44 | Spencer Lodge No 496 Loyal Order of Moose | Unclassified | $49K | $101K |
| 45 | Spencer Public Library Municipal Trust | Education | $46K | $770K |
| 46 | Veterans of Foreign Wars of the Unites States Dept of Iowa | Unclassified | $32K | $90K |
| 47 | Friends of Clay County Conservation Foundation INC | Environment | $21K | $270K |
| 48 | Clay County Fair Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $20K | $622K |
| 49 | Sunshine Services INC | Employment | $14K | $245K |
| 50 | Rural Utility Solutions | Unclassified | $6K | $142K |
| 51 | Ace and Connie Cory Foundation | Philanthropy, Voluntarism & Grantmaking | $102 | $60K |
| 52 | Spencer Church of Christ | Religion-Related | $0 | $0 |
| 53 | Spencer Alliance for a Creative Economy | Community Improvement & Capacity Building | $0 | $0 |
| 54 | Positively Spencer Youth INC | Mental Health & Crisis Intervention | $0 | $0 |
| 55 | Grand Avenue Improvement Corp. | Community Improvement & Capacity Building | $0 | $0 |
| 56 | Iowa Lakes Corridor Initiative | Community Improvement & Capacity Building | $0 | $0 |
| 57 | Ancient Free & Accepted Masons of Iowa | Unclassified | $0 | $0 |
| 58 | Knights of Columbus | Unclassified | $0 | $0 |
| 59 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 60 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 61 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 62 | Royal and Select Masters of Iowa | Unclassified | $0 | $0 |
| 63 | Royal Arch Masons of Iowa | Unclassified | $0 | $0 |
| 64 | Knights Templar of the United States of America | Unclassified | $0 | $0 |
| 65 | Friends of the Old Spencer High School Auditorium INC | Arts, Culture & Humanities | $0 | $0 |
| 66 | Faith Lutheran Church Spencer | Unclassified | $0 | $0 |
| 67 | Royal Historical Society INC | Arts, Culture & Humanities | $0 | $0 |
| 68 | Department of Iowa Auxiliary to the Veterans of Foreign Wars | Public & Societal Benefit | $0 | $0 |
| 69 | Veterans Hall INC | Public & Societal Benefit | $0 | $0 |
| 70 | Outreach Spencer INC | Food, Agriculture & Nutrition | $0 | $0 |
| 71 | Spencer Volunteer Fire Department INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 72 | Iowa Great Lakes Kennel Club | Animal-Related | $0 | $0 |
| 73 | Guy Allen Academy INC | Education | $0 | $0 |
| 74 | Spencer Strong Pink Ladies | Diseases, Disorders & Medical Disciplines | $0 | $0 |
| 75 | Still Waters Recovery | Mental Health & Crisis Intervention | $0 | $0 |
| 76 | Tiger Sports Academy INC | Recreation & Sports | $0 | $0 |
| 77 | American Legion | Unclassified | $0 | $0 |
| 78 | Sacred Heart of Jesus R C Church | Unclassified | $0 | $0 |
| 79 | First English Lutheran Church | Unclassified | $0 | $0 |
| 80 | First Congregational Church of Spencer Ia INC | Unclassified | $0 | $0 |
| 81 | First Christian Church | Unclassified | $0 | $0 |
| 82 | Lutheran Congregation in Mission for Christ | Unclassified | $0 | $0 |
| 83 | Judicial Election District 3A Bar Association | Unclassified | $0 | $0 |
| 84 | Calvary Bible Church | Unclassified | $0 | $0 |
| 85 | Foundation Church | Unclassified | $0 | $0 |
| 86 | Spencer Chapter 1069 Women of the Moose | Unclassified | $0 | $0 |
| 87 | Living Word Outreach Ministries | Religion-Related | $0 | $0 |
| 88 | Christ the King Lutheran Church | Unclassified | $0 | $0 |
| 89 | Avenue of Flags INC | Unclassified | $0 | $0 |
| 90 | Clay County Pals INC | Unclassified | $0 | $0 |
| 91 | Victory Christian Outreach INC | Unclassified | $0 | $0 |
| 92 | Spencer Area Cardinals INC | Unclassified | $0 | $0 |
| 93 | Sioux Valley Chapter of the American Orff- Schulwerk | Unclassified | $0 | $0 |
| 94 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 95 | Crimestoppers of Clay County INC | Unclassified | $0 | $0 |
| 96 | Reins of Hope | Human Services | $0 | $0 |
| 97 | Spencer Alano INC | Mental Health & Crisis Intervention | $0 | $0 |
| 98 | Western Iowa Synodical Womens Org | Unclassified | $0 | $0 |
| 99 | Kiwanis International INC | Unclassified | $0 | $0 |
| 100 | Iowa Great Lakes Lutheran School | Unclassified | $0 | $0 |