| 1 | Siskiyou Hospital INC | Health Care | $129.8M | $121.8M |
| 2 | Lillys Gift Foundation | Philanthropy, Voluntarism & Grantmaking | $11.0M | $30.0M |
| 3 | Siskiyou Credit Union | Unclassified | $9.0M | $146.6M |
| 4 | Siskiyou County Economic Development Council | Community Improvement & Capacity Building | $4.4M | $3.5M |
| 5 | Tri Valley Medical INC | Unclassified | $4.3M | $115.8M |
| 6 | United Scholarships Incorporated | Education | $4.1M | $3.9M |
| 7 | Madrone Hospice INC | Human Services | $3.3M | $6.7M |
| 8 | 10TH District Junior Livestock Auction Committee INC | Education | $2.8M | $4.2M |
| 9 | Ore-cal Resource Conservation and Development Area Council | Environment | $1.8M | $1.4M |
| 10 | Rescue Ranch | Animal-Related | $1.5M | $920K |
| 11 | Siskiyou Family YMCA INC | Human Services | $1.2M | $4.3M |
| 12 | Siskiyou Community Resource Collaborative | Human Services | $1.1M | $877K |
| 13 | Siskiyou County Job Council | Employment | $1.0M | $965K |
| 14 | Siskiyou Domestic Violence & Crisis Center | Human Services | $978K | $812K |
| 15 | Youth Empowerment Siskiyou | Crime & Legal-Related | $971K | $491K |
| 16 | Graham Family Foundation | Philanthropy, Voluntarism & Grantmaking | $724K | $5.1M |
| 17 | Siskiyou Community Food Bank | Food, Agriculture & Nutrition | $352K | $1.4M |
| 18 | Benevolent & Protective Order of Elks of the USA | Unclassified | $347K | $181K |
| 19 | Siskiyou County Farm Bureau | Unclassified | $261K | $222K |
| 20 | Siskiyou Spay Neuter Incentive Program | Animal-Related | $252K | $320K |
| 21 | Fairchild Medical Center Foundation INC | Health Care | $180K | $3.0M |
| 22 | Stable Hands | Health Care | $166K | $216K |
| 23 | Purr-angels | Animal-Related | $148K | $279K |
| 24 | Wild Horse Fire Brigade | Animal-Related | $142K | $224K |
| 25 | Free & Accepted Masons of California | Unclassified | $130K | $54K |
| 26 | Little League Baseball INC | Unclassified | $115K | $70K |
| 27 | Liberty Painting Corp. | Unclassified | $110K | $47K |
| 28 | Siskiyou County Rolling Hills Mutual Water Co INC | Mutual & Membership Benefit | $89K | $387K |
| 29 | Organized Employees of Siskiyou County | Employment | $89K | $119K |
| 30 | Siskiyou County Library Vestal Foundation | Philanthropy, Voluntarism & Grantmaking | $85K | $919K |
| 31 | Habitat for Humanity International INC | Unclassified | $40K | $1.1M |
| 32 | Shasta Watershed Conservation Group INC | Food, Agriculture & Nutrition | $17K | $5K |
| 33 | Siskiyou Gardens Parks and Greenways Association | Environment | $10K | $37K |
| 34 | California Garden Clubs INC | Environment | $0 | $0 |
| 35 | California Assessors Association | Community Improvement & Capacity Building | $0 | $0 |
| 36 | Church at Yreka | Religion-Related | $0 | $0 |
| 37 | American Legion | Unclassified | $0 | $0 |
| 38 | Masonic Temple Association of Yreka | Unclassified | $0 | $0 |
| 39 | Genealogical Society of Siskiyou County California INC | Unclassified | $0 | $0 |
| 40 | Little Shasta Congregational Community Church of Little Shasta | Unclassified | $0 | $0 |
| 41 | Order of the Eastern Star of California | Unclassified | $0 | $0 |
| 42 | Chapter 73 Ecv INC | Mutual & Membership Benefit | $0 | $0 |
| 43 | Friends of Hibbard Field | Recreation & Sports | $0 | $0 |
| 44 | Siskiyou County Canine Association | Crime & Legal-Related | $0 | $0 |
| 45 | Siskiyou County Water Users Association INC | Community Improvement & Capacity Building | $0 | $0 |
| 46 | Yreka Community Certified Farmers Market | Food, Agriculture & Nutrition | $0 | $0 |
| 47 | Tops Club INC | Health Care | $0 | $0 |
| 48 | Yreka Rotary Club Foundation | Community Improvement & Capacity Building | $0 | $0 |
| 49 | Fmc Training and Education | Education | $0 | $0 |
| 50 | Big E Family Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 51 | Yreka Firefighters Association | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 52 | Friends of the Shasta River | Environment | $0 | $0 |
| 53 | Yreka Preservation Corporation | Arts, Culture & Humanities | $0 | $0 |
| 54 | Pastor of St. Joseph Parish - Yreka a Corporation Sole | Unclassified | $0 | $0 |
| 55 | Siskiyou County Veterans Leadership Council | Human Services | $0 | $0 |
| 56 | Yreka PTO | Education | $0 | $0 |
| 57 | Siskiyou County Sheriff Search and Rescue Association | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 58 | International Association of Machinists & Aerospace Workers | Unclassified | $0 | $0 |
| 59 | Siskiyou Police Activities League INC | Youth Development | $0 | $0 |
| 60 | Miner Power INC | Education | $0 | $0 |
| 61 | Berean Fundamental Church of Yreka California | Unclassified | $0 | $0 |
| 62 | Christian Faith Tabernacle INC | Religion-Related | $0 | $0 |
| 63 | Siskiyou Mountain Men | Unclassified | $0 | $0 |
| 64 | Yreka Adventist Christian School | Unclassified | $0 | $0 |
| 65 | Lighthouse of Deliverance | Unclassified | $0 | $0 |
| 66 | Yreka Clay Bird Club INC | Unclassified | $0 | $0 |
| 67 | Marine Corps League | Unclassified | $0 | $0 |
| 68 | Religious Science International | Unclassified | $0 | $0 |
| 69 | Yreka Tennis Club | Recreation & Sports | $0 | $0 |
| 70 | The Lane Street Effort | Human Services | $0 | $0 |
| 71 | Native American Church of the Ghost Dancers | Religion-Related | $0 | $0 |
| 72 | Siskiyou Heat Softball Club | Recreation & Sports | $0 | $0 |
| 73 | Yreka Elementary Faculty Association Yefa | Employment | $0 | $0 |
| 74 | Friends of the Yreka Library INC | Education | $0 | $0 |
| 75 | Yreka Jr Miners Booster Club | Recreation & Sports | $0 | $0 |
| 76 | Siskiyou County Beekeepers Association | Environment | $0 | $0 |
| 77 | Friends of the Siskiyou County Museum | Arts, Culture & Humanities | $0 | $0 |
| 78 | Siskiyou County Off-road Riders | Community Improvement & Capacity Building | $0 | $0 |
| 79 | Riverside Christian Transformation Center | Religion-Related | $0 | $0 |
| 80 | Yreka Food Bank | Food, Agriculture & Nutrition | $0 | $0 |
| 81 | Volcanic Legacy Community Partnership | Environment | $0 | $0 |
| 82 | Abide33 INC | Human Services | $0 | $0 |
| 83 | Greenhorn Disc Golf Club | Recreation & Sports | $0 | $0 |
| 84 | Siskiyouworks | Community Improvement & Capacity Building | $0 | $0 |
| 85 | Toastmasters International | Arts, Culture & Humanities | $0 | $0 |
| 86 | California Resource Conservation and Development Council Associatio | Food, Agriculture & Nutrition | $0 | $0 |
| 87 | Independent Order of Odd Fellows | Unclassified | $0 | $0 |
| 88 | Siskiyou Performing Arts Center INC | Arts, Culture & Humanities | $0 | $0 |
| 89 | Bethel Assembly of God | Unclassified | $0 | $0 |
| 90 | Yreka Foursquare Church | Unclassified | $0 | $0 |
| 91 | Independent Assemblies of God | Unclassified | $0 | $0 |
| 92 | Red Scarf Society for the Performing Arts | Human Services | $0 | $0 |
| 93 | South Yreka Firefighters Auxiliary | Unclassified | $0 | $0 |
| 94 | California Teachers Association | Unclassified | $0 | $0 |
| 95 | Siskiyou County Historical Society | Unclassified | $0 | $0 |
| 96 | Neighborhood Church of Christ | Unclassified | $0 | $0 |
| 97 | National Society of the Daughters of the American Revolution | Human Services | $0 | $0 |
| 98 | Rotary International | Unclassified | $0 | $0 |
| 99 | Falcon Theatrical Group | Arts, Culture & Humanities | $0 | $0 |
| 100 | Synergy Athletics | Recreation & Sports | $0 | $0 |