| 1 | Yuma Regional Medical Center | Health Care | $1.0B | $1.5B |
| 2 | Sunset Community Health Center | Health Care | $45.6M | $76.0M |
| 3 | Yuma Community Food Bank | Food, Agriculture & Nutrition | $21.0M | $10.0M |
| 4 | Harvest Power Community Development Group INC | Education | $20.0M | $24.4M |
| 5 | Saguaro Foundation Community Home Program | Human Services | $19.7M | $15.6M |
| 6 | Achieve Human Services INC | Mental Health & Crisis Intervention | $13.7M | $7.7M |
| 7 | Yuma County Water Users Association | Public & Societal Benefit | $13.0M | $55.9M |
| 8 | Yuma Private Industry Council Incorporated | Unclassified | $11.4M | $4.3M |
| 9 | Foundation of Yuma Regional Medical Center | Health Care | $11.1M | $24.0M |
| 10 | Juniper Tree Academy | Education | $9.7M | $15.2M |
| 11 | Yuma Catholic High School-yuma Arizona | Education | $8.9M | $10.5M |
| 12 | Crossroads Mission | Human Services | $7.9M | $8.7M |
| 13 | Hospice of Yuma | Human Services | $5.4M | $8.1M |
| 14 | Yuma County Fair INC | Unclassified | $4.2M | $11.1M |
| 15 | Humane Society of Yuma INC | Animal-Related | $3.7M | $8.3M |
| 16 | Yuma Golf & Country Club | Unclassified | $3.4M | $2.9M |
| 17 | Yuma Crossing National Heritage Area Corporation | International, Foreign Affairs & National Security | $3.1M | $2.1M |
| 18 | Carpe Diem Collegiate High School | Education | $2.8M | $4.2M |
| 19 | Benevolent & Protective Order of Elks of the USA | Unclassified | $2.0M | $6.2M |
| 20 | Amberlys Place INC | Crime & Legal-Related | $1.9M | $3.4M |
| 21 | Arizona Western College Foundation | Unclassified | $1.8M | $8.0M |
| 22 | Child & Family Services of Yuma INC | Human Services | $1.4M | $3.2M |
| 23 | Yuma Visitors Bureau | Unclassified | $1.3M | $174K |
| 24 | Caballeros de Yuma INC | Unclassified | $1.2M | $1.6M |
| 25 | School Tuition Association of Yuma INC | Education | $1.2M | $749K |
| 26 | Healing Journey INC | Food, Agriculture & Nutrition | $1.1M | $25K |
| 27 | Yumas Education Scholarship Fund for Kids INC | Philanthropy, Voluntarism & Grantmaking | $1.1M | $1.3M |
| 28 | Yuma Lodge No 1627 Loyal Order of Moose | Unclassified | $983K | $1.5M |
| 29 | Art of Intelligent Minds | Mental Health & Crisis Intervention | $959K | $71K |
| 30 | American Legion | Unclassified | $954K | $820K |
| 31 | Fraternal Order of Eagles | Unclassified | $954K | $1.3M |
| 32 | Greater Yuma Economic Development Corporation | Unclassified | $936K | $493K |
| 33 | Yuma Area Housing Opportunity INC | Housing & Shelter | $890K | $577K |
| 34 | Yuma Enterprise Services INC | Human Services | $627K | $216K |
| 35 | Childrens Museum of Yuma County INC | Arts, Culture & Humanities | $590K | $769K |
| 36 | Yuma Christian Academy INC | Education | $584K | $1.8M |
| 37 | Outreach Partners of Yuma INC | Human Services | $584K | $1.3M |
| 38 | Arizona Housing Development Corporation | Housing & Shelter | $570K | $3.0M |
| 39 | Yuma County Chamber of Commerce | Unclassified | $519K | $36K |
| 40 | Adult Literacy Plus of Southwest Arizona | Unclassified | $519K | $517K |
| 41 | Western Association of Educational Opportunity Personnel | Education | $498K | $479K |
| 42 | Stephen H Sturges & Rose P Sturges Charitable Trust | Unclassified | $488K | $5.3M |
| 43 | Pasquinelli Foundation | Unclassified | $444K | $558K |
| 44 | Korean War Veterans Association INC | Public & Societal Benefit | $428K | $868K |
| 45 | Silver Spur Rodeo INC | Arts, Culture & Humanities | $413K | $228K |
| 46 | Casa Sierra Vista INC | Housing & Shelter | $413K | $537K |
| 47 | United Way of Yuma County INC | Philanthropy, Voluntarism & Grantmaking | $408K | $326K |
| 48 | Services Maximizing Independent Living and Empowerment | Health Care | $398K | $291K |
| 49 | Yuma Southwest Contractors Association | Community Improvement & Capacity Building | $364K | $279K |
| 50 | The Ballet Alliance | Unclassified | $355K | $219K |
| 51 | Relevant Media INC | Religion-Related | $340K | $840K |
| 52 | Rsl-az Yuma | Recreation & Sports | $333K | $104K |
| 53 | El Toro Foundation | Unclassified | $287K | $514K |
| 54 | American Federation of Government Employees | Unclassified | $278K | $192K |
| 55 | Casa de la Esperanza Homes of Hope Corporation | International, Foreign Affairs & National Security | $278K | $292K |
| 56 | Veterans of Foreign Wars of the United States Dept of Arizona | Unclassified | $276K | $184K |
| 57 | Disabled American Veterans | Public & Societal Benefit | $267K | $414K |
| 58 | Jazz of Yuma INC | Arts, Culture & Humanities | $261K | $112K |
| 59 | Yuma Catch and Go Flag Football | Unclassified | $253K | $26K |
| 60 | Hand in Hand Christian Preschool INC | Education | $247K | $104K |
| 61 | Fraternal Order of Eagles | Unclassified | $242K | $1.1M |
| 62 | Yuma County Historical Society INC | Arts, Culture & Humanities | $240K | $1.2M |
| 63 | Yuma Multiversity Campus Corporation | Community Improvement & Capacity Building | $239K | $108K |
| 64 | Cooks Foundation | Human Services | $228K | $2.6M |
| 65 | The Hansen House | Health Care | $225K | $181K |
| 66 | Barnabas Association Mexico INC | Religion-Related | $219K | $168K |
| 67 | Ballet Yuma | Education | $218K | $198K |
| 68 | Rotary International | Unclassified | $217K | $117K |
| 69 | Rotary International | Unclassified | $207K | $222K |
| 70 | Yuma Youth Soccer Association | Recreation & Sports | $201K | $55K |
| 71 | Arizona Child and Family Advocacy Center Network | Crime & Legal-Related | $185K | $40K |
| 72 | Yuma Aquatics | Recreation & Sports | $182K | $32K |
| 73 | Western Arizona Community Alliance INC | Housing & Shelter | $180K | $18K |
| 74 | Hunters Army INC | Diseases, Disorders & Medical Disciplines | $178K | $150K |
| 75 | Southwest Health | Health Care | $177K | $585K |
| 76 | Kids at Hope Yuma County Az Chapter | Education | $174K | $62K |
| 77 | Yuma Library Foundation | Arts, Culture & Humanities | $173K | $2.4M |
| 78 | Helping Hands of Yuma | Human Services | $172K | $139K |
| 79 | Jessies Closet Foster Child Resource Center INC | Human Services | $164K | $70K |
| 80 | National Rural Letter Carriers Association | Unclassified | $157K | $395K |
| 81 | Yuma Boys Baseball League | Recreation & Sports | $157K | $145K |
| 82 | International Association of Fire Fighters | Employment | $146K | $137K |
| 83 | Agape Clinic INC | Health Care | $145K | $134K |
| 84 | Churchmexico | Unclassified | $143K | $20K |
| 85 | Purr Project Animal Rescue | Animal-Related | $140K | $24K |
| 86 | Osman Foundation INC | Philanthropy, Voluntarism & Grantmaking | $140K | $26K |
| 87 | Yuma Youth Hockey INC | Recreation & Sports | $135K | $112K |
| 88 | Yuma Trap & Skeet Club INC | Unclassified | $132K | $215K |
| 89 | American Legion | Unclassified | $132K | $145K |
| 90 | Desert Grove Mobile Estates Association INC | Housing & Shelter | $131K | $362K |
| 91 | Arizona Chapter of the Association of Family and Conciliation Courts | Unclassified | $128K | $84K |
| 92 | Gowan Science Academy PTO | Education | $125K | $49K |
| 93 | Yuma East Country Club INC | Unclassified | $122K | $112K |
| 94 | Optimist International | Unclassified | $121K | $149K |
| 95 | Society of St. Vincent Depaul St. Francis of Assisi Conference Yuma | Human Services | $121K | $7K |
| 96 | Western Arizona Council of Emergency Medical Services | Unclassified | $120K | $34K |
| 97 | Adair Ranges INC | Recreation & Sports | $108K | $390K |
| 98 | Communication Workers of America | Unclassified | $104K | $251K |
| 99 | Robert K Barkley Family Foundation | Unclassified | $100K | $56K |
| 100 | 4TH Ave Gym Foundation INC | Recreation & Sports | $99K | $148K |