| 1 | Mariposa Community Health Center INC | Health Care | $62.7M | $48.9M |
| 2 | Diabetes Prevention and Aid Fund INC | Food, Agriculture & Nutrition | $40.4M | $970K |
| 3 | Santa Cruz Training Programs INC | Employment | $5.3M | $5.0M |
| 4 | St. Andrews Childrens Clinic INC | Unclassified | $4.7M | $477K |
| 5 | Mexicayotl Academy of Excellence | Education | $4.2M | $4.8M |
| 6 | Fresh Produce Association of the Americas | Unclassified | $2.7M | $1.9M |
| 7 | Paula and Cabot Sedgwick Family Foundation | Food, Agriculture & Nutrition | $2.2M | $11.5M |
| 8 | Southeast Arizona Area Health Education Center INC | Health Care | $1.4M | $1.1M |
| 9 | Construyendo Circules de Paz-constructing Circles of Peace | Human Services | $1.1M | $540K |
| 10 | House of Life and Hope INC | Philanthropy, Voluntarism & Grantmaking | $965K | $497K |
| 11 | Boys & Girls Club of Santa Cruz County INC | Unclassified | $779K | $1.2M |
| 12 | Border Youth Tennis Exchange INC | Recreation & Sports | $663K | $294K |
| 13 | Az Cyber Initiative | Community Improvement & Capacity Building | $500K | $106K |
| 14 | Cross Roads Nogales Mission INC | Human Services | $464K | $78K |
| 15 | United Church Village INC | Housing & Shelter | $340K | $355K |
| 16 | Santa Cruz Humane Society INC | Animal-Related | $323K | $361K |
| 17 | Chalon Living INC | Housing & Shelter | $315K | $1.1M |
| 18 | Nogales Community Development Corporation | Community Improvement & Capacity Building | $263K | $4.0M |
| 19 | The United Way of Santa Cruz County Arizona INC | Philanthropy, Voluntarism & Grantmaking | $248K | $117K |
| 20 | Nogales Arizona Chamber of Commerce | Unclassified | $212K | $119K |
| 21 | Pimeria Alta Historical Society | Arts, Culture & Humanities | $192K | $46K |
| 22 | Nogales Educational Foundation INC | Education | $179K | $406K |
| 23 | The Fairborn Observatory | Unclassified | $176K | $576K |
| 24 | Os3 Movement | Recreation & Sports | $172K | $5K |
| 25 | Nogales Station Welfare and Recreation Association | Human Services | $148K | $15K |
| 26 | Nogales High School Hall of Fame INC | Education | $132K | $264K |
| 27 | Shipley Family Foundation | Education | $120K | $935K |
| 28 | Rebuilding Together-santa Cruz County INC | Housing & Shelter | $95K | $52K |
| 29 | Asociacion de Maquiladoras de Sonora Ac INC | Community Improvement & Capacity Building | $84K | $81K |
| 30 | Arc of Arizona INC | Unclassified | $66K | $935K |
| 31 | La Linea Art Studio | Arts, Culture & Humanities | $61K | $38K |
| 32 | Santa Cruz County Young Audiences INC | Arts, Culture & Humanities | $56K | $18K |
| 33 | Cultural Arts Committe of Nogales Arizona | Arts, Culture & Humanities | $45K | $33K |
| 34 | Luis & Alma Moreno Foundation | Human Services | $25K | $25K |
| 35 | Associated Charities of Nogales INC | Unclassified | $19K | $73K |
| 36 | Panousopoulos Scholastic Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $7K | $513K |
| 37 | Robert and Kimberly Milo Foundation | Human Services | $1 | $38K |
| 38 | Friends of the Library | Education | $0 | $0 |
| 39 | Nogales Infantil | Community Improvement & Capacity Building | $0 | $0 |
| 40 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 41 | Centro Familiar Cristiano de Nogales | Unclassified | $0 | $0 |
| 42 | Centro Cristiano Nueva Cosecha | Religion-Related | $0 | $0 |
| 43 | Club de Oriundos Nogalenses En Arizona | Human Services | $0 | $0 |
| 44 | Knights of Columbus | Unclassified | $0 | $0 |
| 45 | Roca Viva Asamblea de Dios | Unclassified | $0 | $0 |
| 46 | Auxilio Divino de Las Asambleas de Dios | Unclassified | $0 | $0 |
| 47 | Wildfire Protection INC | Public Safety, Disaster Preparedness & Relief | $0 | $0 |
| 48 | Creser-cultural and Resource Center for Women and Their Families INC | Human Services | $0 | $0 |
| 49 | Renaissance Coalition | Unclassified | $0 | $0 |
| 50 | Centro Cristiano Emanuel | Unclassified | $0 | $0 |
| 51 | Arizonas Center for Agricultural Advancement | Food, Agriculture & Nutrition | $0 | $0 |
| 52 | Making Connections 4U Santa Cruz Community Action Coalition | Community Improvement & Capacity Building | $0 | $0 |
| 53 | Horses for Veterans | Human Services | $0 | $0 |
| 54 | Agape Outreach House INC | Human Services | $0 | $0 |
| 55 | Ichange Volunteer | International, Foreign Affairs & National Security | $0 | $0 |
| 56 | Ivans Choice Leukemia Foundation | Human Services | $0 | $0 |
| 57 | Nogales Police Officers Association | Mutual & Membership Benefit | $0 | $0 |
| 58 | Rotary Club of Nogales Foundation INC | Unclassified | $0 | $0 |
| 59 | Santa Cruz Advocates for the Arts | Arts, Culture & Humanities | $0 | $0 |
| 60 | Nogales U S Customs Brokers Association | Community Improvement & Capacity Building | $0 | $0 |
| 61 | Southern Arizona Autism Association | Diseases, Disorders & Medical Disciplines | $0 | $0 |
| 62 | Edify Our Families | Human Services | $0 | $0 |
| 63 | Santa Cruz Childrens Museum INC | Arts, Culture & Humanities | $0 | $0 |
| 64 | Iglesia Luz de la Frontera Border Light Church Gracia Para Todos | Religion-Related | $0 | $0 |
| 65 | Freinds of Las Lagunas INC | Environment | $0 | $0 |
| 66 | Triple Nickel | Youth Development | $0 | $0 |
| 67 | Explorer Post 125 Advisor Association | Youth Development | $0 | $0 |
| 68 | Santa Cruz Center Educational Foundation | Education | $0 | $0 |
| 69 | Nogales Port of Entry Morale Welfare and Recreation Association | Community Improvement & Capacity Building | $0 | $0 |
| 70 | Bethel-tucson Church of God | Unclassified | $0 | $0 |
| 71 | Charros Baseball | Recreation & Sports | $0 | $0 |
| 72 | Instituto Biblico Mexicano | Unclassified | $0 | $0 |
| 73 | Mexican Baptist Church and Missions INC | Unclassified | $0 | $0 |
| 74 | Nogales Womans Club | Community Improvement & Capacity Building | $0 | $0 |
| 75 | Mission of the Loving Shepherd INC | Unclassified | $0 | $0 |
| 76 | United Churches Fellowship | Unclassified | $0 | $0 |
| 77 | Abundant Life Assembly of God | Unclassified | $0 | $0 |
| 78 | City of Nogales Employee Benefit Trust | Unclassified | $0 | $0 |
| 79 | Nogales High School Band Boosters | Arts, Culture & Humanities | $0 | $0 |
| 80 | Internationa Association of Fire Fighters | Employment | $0 | $0 |
| 81 | Companeros En Mision | Religion-Related | $0 | $0 |
| 82 | Bahais of Nogales | Unclassified | $0 | $0 |
| 83 | Faith Christian Fellowship of Nogales | Unclassified | $0 | $0 |
| 84 | St. Andrews General Endowment Fund | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 85 | Agape Ministries INC | Religion-Related | $0 | $0 |
| 86 | Big Chuy Memorial Foundation | Health Care | $0 | $0 |
| 87 | Arizona Quail Alliance | Animal-Related | $0 | $0 |
| 88 | Auxilio Divino de Las Asambleas de Dios | Unclassified | $0 | $0 |
| 89 | National Association of Letter Carriers | Unclassified | $0 | $0 |
| 90 | Rotary International | Unclassified | $0 | $0 |
| 91 | International Association of Lions Clubs | Unclassified | $0 | $0 |
| 92 | 2763 Fire Fighters Charities INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 93 | Urge Medical INC | Education | $0 | $0 |
| 94 | San Carlos Pickleball Club International INC | Recreation & Sports | $0 | $0 |
| 95 | Por Mi Nogalitos | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 96 | Brothers and Sisters of Charity INC | Food, Agriculture & Nutrition | $0 | $0 |
| 97 | Apache Jazz Boosters | Education | $0 | $0 |
| 98 | Toastmasters International | Unclassified | $0 | $0 |
| 99 | Toastmasters International | Unclassified | $0 | $0 |
| 100 | Nhs Volleyball | Education | $0 | $0 |