| 1 | The Community Fdn of Middle Tn INC Nashville | $524.7M | $239.9M | $832.0M |
| 2 | Bill and Crissy Haslam Foundation Knoxville | $228.1M | $0 | $171.4M |
| 3 | Community Foundation of Greater Memphis INC Memphis | $171.4M | $171.4M | $953.1M |
| 4 | Christian Community Foundation of Memphis and the Mid-south INC Memphis | $168.6M | $112.2M | $218.6M |
| 5 | The Frist Foundation Nashville | $120.2M | $0 | $195.6M |
| 6 | McDonnell Family Foundation Memphis | $100.2M | $0 | $133.2M |
| 7 | Gary Sinise Foundation Franklin | $97.9M | $85.5M | $89.0M |
| 8 | Scarlett Family Foundation Nashville | $89.2M | $0 | $249.3M |
| 9 | Living Legacy Foundation Nashville | $84.5M | $0 | $164.8M |
| 10 | Assisi Foundation of Memphis INC Memphis | $78.4M | $0 | $222.9M |
| 11 | Community Foundation of Greater Chattanooga INC Chattanooga | $70.6M | $48.0M | $245.3M |
| 12 | United Way of Middle Tennessee INC Nashville | $68.2M | $46.2M | $70.3M |
| 13 | The Haslam 3 Foundation INC Knoxville | $54.9M | $0 | $88.7M |
| 14 | Chattanooga Christian Community Foundation Chattanooga | $54.8M | $53.6M | $136.1M |
| 15 | Dettwiller Foundation Nashville | $50.7M | $0 | $251.3M |
| 16 | Ted and Drama Russell Family Foundation Knoxville | $38.7M | $6.4M | $107.5M |
| 17 | Topher-scott Foundation INC Knoxville | $35.8M | $0 | $52.0M |
| 18 | Fully Alive Foundation INC Knoxville | $35.2M | $0 | $52.0M |
| 19 | Elizabeth Turner Campbell Foundatio Franklin | $34.4M | $0 | $70.5M |
| 20 | Haslam Family Foundation INC Knoxville | $30.7M | $0 | $19.3M |
| 21 | East Tennessee Foundation Knoxville | $30.6M | $27.7M | $282.5M |
| 22 | Aslan Foundation Knoxville | $27.8M | $0 | $122.0M |
| 23 | Herbert a Fritch Family Foundation Nashville | $26.5M | $0 | $32.5M |
| 24 | Boyd Foundation Knoxville | $26.3M | $0 | $98.0M |
| 25 | Yarbrough Family Foundation Franklin | $24.2M | $0 | $24.1M |
| 26 | Daryl and Mary Pennington Foundation INC Brentwood | $22.2M | $0 | $34.1M |
| 27 | Formanek Foundation Memphis | $22.0M | $0 | $155.4M |
| 28 | Ahb Foundation Knoxville | $20.6M | $0 | $46.0M |
| 29 | Speer Foundation Brentwood | $20.4M | $0 | $131.2M |
| 30 | United Way of Greater Chattanooga Chattanooga | $20.0M | $12.1M | $32.9M |
| 31 | Colquitt Foundation Knoxville | $19.6M | $0 | $30.5M |
| 32 | Beth and Preston Ingram Foundation INC Franklin | $19.0M | $0 | $17.8M |
| 33 | Robert E and Jenny D Kirkland Found Union City | $18.7M | $0 | $301.1M |
| 34 | Grace Foundation of Memphis INC Memphis | $18.6M | $0 | $30.9M |
| 35 | United Way of the Mid-south Memphis | $18.2M | $17.2M | $18.1M |
| 36 | The Judith E and Joseph C Cook Jr Foundation INC Nashville | $16.9M | $0 | $50.6M |
| 37 | Isaacson Foundation Gallatin | $16.7M | $0 | $11.8M |
| 38 | James and Laura Rogers Foundation Kingsport | $16.3M | $0 | $25.4M |
| 39 | Crews Family Foundation Germantown | $15.5M | $0 | $108.3M |
| 40 | The Shepherds Foundation INC Franklin | $15.4M | $0 | $23.3M |
| 41 | Lane Motor Museum Nashville | $14.8M | $0 | $17.3M |
| 42 | The Martin Family Foundation INC Memphis | $14.6M | $14.6M | $25.8M |
| 43 | McGehee Family Foundation Memphis | $14.3M | $0 | $10.6M |
| 44 | Haver Foundation Brentwood | $12.9M | $0 | $21.5M |
| 45 | Mike Curb Foundation Nashville | $12.8M | $0 | $35.4M |
| 46 | Milton and Denice Johnson Family Foundation Nashville | $12.6M | $0 | $32.1M |
| 47 | National Christian Charitable Foundation INC Knoxville | $12.4M | $12.4M | $14.2M |
| 48 | A&t Family Foundation INC Maryville | $12.0M | $0 | $10.7M |
| 49 | Dugas Family Foundation II INC Nashville | $11.5M | $0 | $24.3M |
| 50 | Nashville State Community College Foundation Nashville | $11.5M | $11.5M | $13.7M |