| 1 | International Rett Syndrome Foundation West Chester | $8.7M | $4.8M | $5.3M |
| 2 | Centers for Dialysis Care Foundation Shaker Hts | $8.5M | $3.0M | $46.4M |
| 3 | Fraternal Order of Eagles Foundation Grove City | $7.5M | $5.1M | $16.0M |
| 4 | Humanitarian Foundation Supreme Council M O V P E R Gahanna | $6.1M | $1.2M | $15.9M |
| 5 | Cleveland Va Medical Research and Education Foundation Cleveland | $5.5M | $5.5M | $4.3M |
| 6 | The Health Collaborative Cincinnati | $5.4M | $5.0M | $4.1M |
| 7 | Cincinnati Sight Restoration Foundation INC Cincinnati | $5.4M | $3.6M | $16.2M |
| 8 | Abraham J and Phyllis Katz Cord Blood Foundation Cleveland | $4.8M | $4.4M | $5.8M |
| 9 | Chaney Family Foundation Lyndhurst | $3.9M | $0 | $4.9M |
| 10 | Brigids Path INC Moraine | $3.5M | $3.3M | $4.1M |
| 11 | Cancer Free Kids Pediatric Cancer Research Alliance Cincinnati | $3.1M | $2.6M | $2.0M |
| 12 | Maple Tree Cancer Alliance Dayton | $1.6M | $1.6M | $785K |
| 13 | Cincinnati Education and Research for Veterans Foundation Cincinnati | $1.5M | $1.5M | $1.1M |
| 14 | Premier Community Health Dayton | $1.3M | $809K | $1.6M |
| 15 | Center for Dialysis Care at Heather Hills Shaker Hts | $1.3M | $1.3M | $255K |
| 16 | Ohio Dermatological Foundation Dalton | $1.2M | $244K | $3.6M |
| 17 | Greater Ohio Bleeding Disorders Foundation INC Cleveland | $1.2M | $1.1M | $1.7M |
| 18 | Taylor Family Research Foundation Maumee | $1.0M | $1.0M | $457K |
| 19 | Cincinnati Eye Institute Foundation Blue Ash | $979K | $960K | $671K |
| 20 | Society for Integrative Oncology INC Pepper Pike | $836K | $836K | $643K |
| 21 | Ride Cincinnati Foundation Cincinnati | $768K | $768K | $420K |
| 22 | Ohio Cancer Research Associates Columbus | $765K | $580K | $582K |
| 23 | Steven G Aya Cancer Research Fund Avon Lake | $733K | $733K | $138K |
| 24 | The Orthopedic Foundation Westerville | $717K | $422K | $1.5M |
| 25 | Awakening Angels Westlake | $655K | $500K | $3.2M |
| 26 | Friends of the Rich Center for Autism Youngstown | $618K | $415K | $936K |
| 27 | Beacon Orthopaedic Research & Education Foundation Cincinnati | $545K | $342K | $47K |
| 28 | Alliance of Independent Academic Medical Centers Canton | $433K | $433K | $198K |
| 29 | Neurotech Institute INC Columbus | $353K | $353K | $6.1M |
| 30 | Research Society for Personality & Psychopathology INC Columbus | $285K | $285K | $374K |
| 31 | Jis Research Institute New Albany | $237K | $237K | $68K |
| 32 | Dayton Veterans Affairs Research and Education Foundation Dayton | $193K | $193K | $641K |
| 33 | Breast Cancer Fund of Ohio Independence | $193K | $193K | $134K |
| 34 | Rockin Out Cancer Lewis Center | $191K | $134K | $13K |
| 35 | Biodynamic Craniosacral Therapy Association of North America Aurora | $188K | $188K | $158K |
| 36 | Rubi Girls INC Dayton | $176K | $131K | $287K |
| 37 | Henry McCann Memorial Colorectal Cancer Foundation Columbus | $173K | $132K | $85K |
| 38 | Neomed Research Corporation Rootstown | $172K | $172K | $884K |
| 39 | Ohio Lions Eye Research Foundation Ashland | $161K | $161K | $2.2M |
| 40 | Fibromuscular Dysplasia Society of America INC North Olmsted | $159K | $159K | $135K |
| 41 | Edward Medof Foundation for Excellence in Immunology Pepper Pike | $158K | $0 | $577K |
| 42 | North Eastern Ohio Radiology Research & Education Fund Canfield | $146K | $0 | $258K |
| 43 | Alex Rezkalla Foundation Powell | $137K | $91K | $27K |
| 44 | Childrens Interstitial Lung Disease Foundation INC Cincinnati | $132K | $132K | $253K |
| 45 | Collincarescurecancer Corp. Medina | $126K | $126K | $21K |
| 46 | Austintown Colts Youth Football Organization Austintown | $118K | $116K | $44K |
| 47 | Lakeview Elementary PTO Cortland | $116K | $116K | $35K |
| 48 | Ray of Hope Foundation Loveland | $113K | $86K | $103K |
| 49 | Carestar Community Services Cincinnati | $112K | $112K | $969K |
| 50 | Allergists for Israel Cincinnati | $107K | $107K | $156K |