| 1 | Lifespace Communities INC Wdm | $393.1M | $391.2M | $1.3B |
| 2 | Wesley Retirement Services INC Johnston | $112.9M | $110.7M | $329.4M |
| 3 | Four Oaks Family and Childrens Services Cedar Rapids | $59.0M | $55.2M | $49.5M |
| 4 | Hawkeye Area Community Action Program INC Hiawatha | $56.6M | $56.6M | $14.1M |
| 5 | Systems Unlimited INC Iowa City | $48.0M | $48.0M | $31.3M |
| 6 | Lutheran Services in Iowa INC Des Moines | $42.1M | $32.6M | $26.2M |
| 7 | Stonehill Franciscan Services Dubuque | $31.3M | $30.6M | $47.0M |
| 8 | Mid-step Services INC Sioux City | $30.7M | $30.7M | $24.1M |
| 9 | Christian Retirement Services INC Oaknoll Retirement Residence Iowa City | $28.1M | $28.1M | $123.7M |
| 10 | Young Mens Christian Association of the Iowa Mississippi Valley Davenport | $27.4M | $16.8M | $69.9M |
| 11 | Exceptional Persons INC Waterloo | $27.4M | $25.3M | $21.3M |
| 12 | Youth and Shelter Services INC Ames | $27.3M | $27.2M | $40.6M |
| 13 | Meth-wick Community Cedar Rapids | $25.6M | $21.8M | $34.9M |
| 14 | Balance Autism Altoona | $24.8M | $24.4M | $21.5M |
| 15 | Mainstream Living INC Stuart Ambrose Ames | $24.1M | $24.1M | $15.3M |
| 16 | Wesley Community Services INC Johnston | $22.4M | $22.4M | $19.7M |
| 17 | Christian Retirement Homes INC Davenport | $20.3M | $17.5M | $22.3M |
| 18 | Martin Health Center INC Cedar Falls | $20.1M | $20.1M | $18.6M |
| 19 | Comprehensive Systems INC Charles City | $20.0M | $20.0M | $5.6M |
| 20 | Northcrest INC Ames | $19.4M | $15.1M | $89.2M |
| 21 | Camp Courageous of Iowa Foundation Monticello | $19.4M | $8.3M | $72.4M |
| 22 | Cottage Grove Place Cedar Rapids | $19.1M | $19.1M | $54.7M |
| 23 | Exira Care Center Corporation Exira | $18.7M | $18.7M | $16.0M |
| 24 | Hillcrest Family Services Dubuque | $18.2M | $16.9M | $22.7M |
| 25 | Childserve Foundation INC Johnston | $17.8M | $14.0M | $22.1M |
| 26 | Village Northwest Unlimited Sheldon | $16.8M | $16.7M | $22.8M |
| 27 | Heartland Goodwill Enterprises Cedar Rapids | $16.7M | $4.7M | $13.7M |
| 28 | Cedar Valley Hospice INC Waterloo | $16.6M | $14.6M | $18.2M |
| 29 | Hope Ministries Des Moines | $16.6M | $15.6M | $39.1M |
| 30 | Hospice of Dubuque Foundation Dubuque | $16.3M | $2.9M | $18.3M |
| 31 | Discovery Living INC Cedar Rapids | $15.6M | $15.5M | $12.5M |
| 32 | Hope Haven Area Development Center Corporation Burlington | $15.3M | $15.6M | $13.0M |
| 33 | Children and Families of Iowa Des Moines | $15.2M | $15.2M | $26.4M |
| 34 | Community Crisis Services and Food Bank Iowa City | $14.7M | $14.4M | $7.3M |
| 35 | Nishna Productions INC Shenandoah | $14.7M | $14.7M | $16.1M |
| 36 | West Central Community Action Harlan | $14.6M | $14.6M | $5.6M |
| 37 | Bartels Lutheran Home Waverly | $14.5M | $14.5M | $42.2M |
| 38 | Mid Sioux Opportunity INC Remsen | $14.3M | $14.3M | $5.7M |
| 39 | Northeast Iowa Comm Action Corp. Decorah | $14.3M | $14.3M | $13.2M |
| 40 | Eastern Star Masonic Home Boone | $13.8M | $13.8M | $20.5M |
| 41 | Community Opportunities INC Carroll | $13.5M | $13.5M | $8.2M |
| 42 | Pride Group Le Mars | $12.2M | $12.2M | $13.6M |
| 43 | Charles E Lakin Human Services Campus Foundation Council Blfs | $11.9M | $10.5M | $17.4M |
| 44 | Opportunity Living Lake City | $11.8M | $11.8M | $6.6M |
| 45 | Mayflower Homes INC Grinnell | $11.1M | $11.1M | $23.3M |
| 46 | Table to Table Food Distribution Network Iowa City | $10.7M | $10.7M | $714K |
| 47 | United Presbyterian Home Washington | $10.3M | $10.3M | $13.6M |
| 48 | Area Residential Care INC Dubuque | $10.0M | $10.0M | $14.4M |
| 49 | Iowa Mennonite Benevolent Association Kalona | $10.0M | $9.8M | $22.6M |
| 50 | Christian Home Association Childrens Square U S a Council Blfs | $10.0M | $9.7M | $12.8M |