| 1 | Genentech Patient Foundation S San Fran | $3.7B | $0 | $424.1M |
| 2 | Aids Healthcare Foundation Los Angeles | $2.5B | $2.2B | $1.6B |
| 3 | Inland Counties Regional Center INC Sn Bernrdno | $1.0B | $1.0B | $328.7M |
| 4 | Pharmacy4humanity Los Angeles | $878.4M | $878.4M | $185.7M |
| 5 | Regional Center of the East Bay INC San Leandro | $832.2M | $832.2M | $386.5M |
| 6 | San Diego Imperial Counties Developmental Services INC San Diego | $820.8M | $820.8M | $151.3M |
| 7 | San Andreas Regional Center San Jose | $758.1M | $758.1M | $113.5M |
| 8 | Regional Center of Orange County Santa Ana | $724.3M | $724.3M | $149.8M |
| 9 | South Central L a Reg Central for Dvlopmntly Disabled Persons INC Los Angeles | $637.0M | $637.0M | $399.1M |
| 10 | Central Valley Regional Center INC Fresno | $630.5M | $630.5M | $331.8M |
| 11 | Sutter Visiting Nurse Association and Hospice Sacramento | $559.3M | $559.2M | $544.8M |
| 12 | Golden Gate Regional Center INC San Francisco | $545.9M | $545.9M | $265.4M |
| 13 | Eastern Los Angeles Regional Center for Developmentally Disabled INC Alhambra | $517.4M | $517.4M | $260.6M |
| 14 | North Bay Developmental Disabilities Services INC Napa | $482.5M | $482.5M | $85.5M |
| 15 | Valley Mountain Regional Center INC Stockton | $453.1M | $453.1M | $23.4M |
| 16 | Harbor Devlopmental Disabilities Foundation Torrance | $411.3M | $411.3M | $140.5M |
| 17 | Los Angeles County Developmental Service Foundation Los Angeles | $398.5M | $398.5M | $59.0M |
| 18 | YMCA of San Diego County San Diego | $347.3M | $317.3M | $250.6M |
| 19 | Pacific Clinics Campbell | $340.5M | $339.4M | $220.2M |
| 20 | Kern Regional Center Bakersfield | $328.8M | $328.8M | $87.8M |
| 21 | Pride Industries Roseville | $312.1M | $295.9M | $143.5M |
| 22 | Far Northern Coordinating Council on Developmental Disabilities Redding | $300.0M | $300.0M | $138.9M |
| 23 | Humangood Norcal Duarte | $291.8M | $224.3M | $740.7M |
| 24 | Tides Center San Francisco | $283.0M | $265.4M | $297.4M |
| 25 | Access Services Incorporated El Monte | $279.3M | $279.2M | $134.8M |
| 26 | Braille Institute of America INC Los Angeles | $227.5M | $83.6M | $311.3M |
| 27 | Special Service for Groups INC Los Angeles | $223.2M | $223.2M | $122.7M |
| 28 | Child Development Associates Incorporated Bonita | $222.4M | $222.4M | $60.0M |
| 29 | Community Eldercare of San Diego San Diego | $213.4M | $156.1M | $109.9M |
| 30 | Childrens Council of San Francisco San Francisco | $212.9M | $212.9M | $56.1M |
| 31 | Young Mens Christian Association of the East Bay Berkeley | $187.7M | $101.1M | $164.5M |
| 32 | Humangood Socal Duarte | $184.3M | $136.4M | $340.1M |
| 33 | People Assisting the Homeless Los Angeles | $181.5M | $181.1M | $65.0M |
| 34 | Community Action Partnership of Kern Bakersfield | $181.3M | $181.3M | $96.7M |
| 35 | Childrens Home Society of California & Affiliated Chapters Los Angeles | $172.0M | $168.1M | $144.2M |
| 36 | Fresno County Economic Opportunities Commission Fresno | $158.9M | $158.9M | $40.2M |
| 37 | Guide Dogs for the Blind INC San Rafael | $157.3M | $91.8M | $572.0M |
| 38 | Masonic Homes of California San Francisco | $155.4M | $116.6M | $1.2B |
| 39 | Young Mens Christian Association of Metropolitan Los Angeles Los Angeles | $154.2M | $112.2M | $280.5M |
| 40 | Child Action Incorporated Rncho Cordova | $152.1M | $152.1M | $51.6M |
| 41 | Center for Elders Independence Oakland | $149.1M | $148.9M | $243.7M |
| 42 | Eskaton Properties Incorporated Carmichael | $147.6M | $73.6M | $150.5M |
| 43 | Canine Companions for Independence Santa Rosa | $146.1M | $54.9M | $212.6M |
| 44 | Crabill Family Foundation San Francisco | $145.0M | $0 | $131.4M |
| 45 | Mind Oc Irvine | $141.6M | $50.4M | $198.1M |
| 46 | Motion Picture and Television Fund Woodland Hls | $136.7M | $74.6M | $125.4M |
| 47 | Covenant Living West Santa Barbara | $134.8M | $133.0M | $439.4M |
| 48 | The Neighborhood House Assn. San Diego | $129.5M | $129.4M | $30.8M |
| 49 | Young Mens Christian Association of San Francisco San Francisco | $129.2M | $119.2M | $122.4M |
| 50 | Sequoia Living INC San Francisco | $128.5M | $119.2M | $448.9M |