| 1 | North Mississippi Medical Center INC Tupelo | $2.0B | $985.1M | $1.6B |
| 2 | St. Dominic-jackson Memorial Hospital Jackson | $632.3M | $596.9M | $567.5M |
| 3 | Mississippi Baptist Medical Center Jackson | $590.9M | $588.0M | $305.4M |
| 4 | Baptist Memorial Hospital-desoto INC Southaven | $357.2M | $357.0M | $290.3M |
| 5 | Baptist Memorial Hospital-north Mississippi INC Oxford | $315.2M | $315.0M | $752.2M |
| 6 | Baptist Memorial Hospital-golden Triangle INC Columbus | $310.1M | $310.1M | $348.7M |
| 7 | Anderson Regional Medical Center Meridian | $288.9M | $284.4M | $121.8M |
| 8 | Baptist Memorial Hospital Union County INC New Albany | $223.8M | $223.7M | $96.9M |
| 9 | Rush Medical Foundation Meridian | $195.9M | $192.6M | $121.2M |
| 10 | Mississippi State University Educational Building Corporation Ms State | $150.9M | $94.9M | $423.5M |
| 11 | Kings Daughters Medical Center Brookhaven | $118.3M | $115.6M | $114.9M |
| 12 | Mississippi Methodist Hospital Rehabilitation Center INC Jackson | $83.2M | $78.8M | $104.9M |
| 13 | North Mississippi Primary Health Care INC Ashland | $80.4M | $80.4M | $78.6M |
| 14 | Medical Foundation of Central Mississippi INC Jackson | $76.2M | $76.0M | $36.7M |
| 15 | Clay County Medical Corporation Tupelo | $66.1M | $66.1M | $51.5M |
| 16 | Monroe Health Services INC Tupelo | $63.4M | $63.4M | $52.0M |
| 17 | North Mississippi Health Services INC Tupelo | $61.0M | $60.1M | $129.8M |
| 18 | North Mississippi Medical Clinics Tupelo | $56.0M | $56.0M | $253.4M |
| 19 | Independent Healthcare Management INC Magee | $49.9M | $49.9M | $33.6M |
| 20 | Medical Foundation INC Non Profit Organization Meridian | $43.1M | $43.1M | $10.2M |
| 21 | Coastal Family Health Center INC Gulfport | $38.7M | $38.7M | $30.5M |
| 22 | Southeast Mississippi Rural Health Initiative INC Hattiesburg | $33.6M | $33.6M | $13.1M |
| 23 | Pontotoc Health Services INC Tupelo | $33.2M | $33.2M | $37.4M |
| 24 | Central Mississippi Civic Improvement Association INC Jackson | $32.0M | $32.0M | $30.4M |
| 25 | St. Catherines Village INC Jackson | $31.9M | $28.1M | $113.1M |
| 26 | Laird Hospital INC Union | $30.1M | $30.1M | $16.4M |
| 27 | Mississippi Organ Recovery Agency Flowood | $28.1M | $25.3M | $24.7M |
| 28 | Baptist Memorial Hospital Booneville INC Booneville | $26.9M | $26.8M | $12.3M |
| 29 | Webster Health Services INC Tupelo | $25.6M | $25.6M | $34.5M |
| 30 | Family Health Care Clinic INC Pearl | $24.9M | $24.9M | $14.7M |
| 31 | Kemper Cah Meridian | $22.4M | $22.4M | $13.3M |
| 32 | Simpson Community Healthcare INC Mendenhall | $21.8M | $21.8M | $8.8M |
| 33 | Rush Hospital-butler INC Meridian | $21.6M | $21.6M | $14.9M |
| 34 | Mississippi Blood Services INC Flowood | $21.3M | $20.4M | $17.4M |
| 35 | Baptist Medical Center-yazoo INC Yazoo City | $21.0M | $21.0M | $9.3M |
| 36 | Baptist Medical Center-leake INC Jackson | $20.9M | $20.9M | $11.4M |
| 37 | G a Carmichael Family Health Center INC Canton | $20.0M | $20.0M | $8.5M |
| 38 | Mississippi Bapt Health Systems INC Jackson | $19.9M | $19.9M | $19.7M |
| 39 | United Methodist Senior Services Health Care INC Tupelo | $19.3M | $19.3M | $6.7M |
| 40 | Tishomingo Health Services INC Tupelo | $18.9M | $18.9M | $9.7M |
| 41 | Marion Regional Medical Center INC Tupelo | $18.7M | $18.7M | $7.6M |
| 42 | Magee Benevolent Association Magee | $18.5M | $18.5M | $8.5M |
| 43 | Jackson Medical Mall Foundation Jackson | $18.3M | $18.3M | $68.2M |
| 44 | St. Luke Foundation McComb | $17.3M | $17.3M | $36.4M |
| 45 | Access Family Health Services INC Smithville | $16.0M | $16.0M | $20.7M |
| 46 | Aaron E Henry Community Health Clarksdale | $15.6M | $15.6M | $8.9M |
| 47 | Bolivar Medical Center Foundation Cleveland | $14.4M | $7.3M | $70.3M |
| 48 | Scott Regional Medical Center INC Meridian | $14.2M | $14.2M | $13.6M |
| 49 | Mississippi Public Health Institute Ridgeland | $12.1M | $12.1M | $2.3M |
| 50 | East Central Mississippi Health Care INC Sebastopol | $11.6M | $11.6M | $8.6M |