| 1 | Central Iowa Hospital Corporation Des Moines | $2.4B | $1.4B | $1.8B |
| 2 | Catholic Health Initiatives-iowa Corp. Des Moines | $978.7M | $977.0M | $1.1B |
| 3 | Mercy Health Services Iowa Corp. Sioux City | $976.0M | $972.7M | $874.1M |
| 4 | Genesis Health System Davenport | $687.8M | $675.7M | $876.8M |
| 5 | Iowa Physicians Clinic Medical Foundation Wdm | $615.7M | $615.1M | $291.8M |
| 6 | Mercy Medical Center Cedar Rapids | $606.5M | $478.8M | $728.2M |
| 7 | St. Lukes Methodist Hospital Cedar Rapids | $554.2M | $502.6M | $636.9M |
| 8 | Allen Memorial Hospital Corporation Waterloo | $477.4M | $443.1M | $448.5M |
| 9 | Iowa Health System Wdm | $443.7M | $442.4M | $1.2B |
| 10 | Southeast Iowa Regional Medical Center INC W Burlington | $438.9M | $438.2M | $266.1M |
| 11 | Covenant Medical Center INC Waterloo | $402.1M | $401.6M | $245.0M |
| 12 | Northwest Iowa Hospital Corporation Sioux City | $275.8M | $254.3M | $238.6M |
| 13 | Care Initiatives Wdm | $272.0M | $271.9M | $173.8M |
| 14 | Trinity Regional Medical Center Fort Dodge | $240.9M | $206.0M | $254.4M |
| 15 | Jennie Edmundson Memorial Hospital Council Blfs | $208.1M | $172.2M | $180.9M |
| 16 | Mercy Clinics INC Des Moines | $203.3M | $203.3M | $275.0M |
| 17 | The Finley Hospital Dubuque | $182.0M | $160.8M | $257.3M |
| 18 | Pella Regional Health Center Pella | $175.6M | $159.6M | $192.4M |
| 19 | Mercy Hospital Iowa City | $138.3M | $19.7M | $44.0M |
| 20 | Mercy Medical Center-clinton INC Clinton | $133.7M | $133.7M | $117.5M |
| 21 | St. Anthony Regional Hospital and Nursing Home Carroll | $127.5M | $113.7M | $212.9M |
| 22 | Marvin M Jorgensen Charitable Tr Urbandale | $102.4M | $100.4M | $105.4M |
| 23 | Unitypoint Health-marshalltown Marshalltown | $87.1M | $86.7M | $90.6M |
| 24 | Unity Healthcare Muscatine | $77.4M | $74.8M | $89.3M |
| 25 | Lifeserve Blood Center Des Moines | $75.1M | $52.4M | $122.4M |
| 26 | Burgess Health Center Onawa | $73.7M | $43.1M | $66.2M |
| 27 | Grinnell Regional Medical Center Grinnell | $71.5M | $71.5M | $36.2M |
| 28 | Shenandoah Medical Center Shenandoah | $70.4M | $67.0M | $85.4M |
| 29 | Henry County Health Center INC Mt Pleasant | $65.5M | $65.5M | $45.1M |
| 30 | Primary Health Care INC Des Moines | $62.5M | $62.4M | $36.7M |
| 31 | Sioux Valley Memorial Hospital Association Cherokee | $60.8M | $60.8M | $109.9M |
| 32 | Iowa Health Foundation Des Moines | $58.7M | $24.6M | $223.4M |
| 33 | Knoxville Community Hospital INC Knoxville | $57.0M | $57.0M | $69.4M |
| 34 | Mercy Medical Center-centerville Centerville | $53.5M | $53.5M | $72.8M |
| 35 | Palmer Lutheran Health Center INC West Union | $50.3M | $50.3M | $40.8M |
| 36 | Wheaton Franciscan Healthcare-iowa INC Waterloo | $50.0M | $50.0M | $34.4M |
| 37 | Siouxland Community Health Center Sioux City | $48.2M | $48.2M | $54.3M |
| 38 | Stewart Memorial Community Hospital Lake City | $46.5M | $46.5M | $58.0M |
| 39 | Virginia Gay Hospital INC Vinton | $44.9M | $44.8M | $58.0M |
| 40 | Sartori Memorial Hospital INC Cedar Falls | $42.9M | $42.8M | $18.2M |
| 41 | Mercy Medical Center-newton Des Moines | $41.6M | $41.6M | $59.2M |
| 42 | Alegent Health-community Memorial Hospital of Missouri Valley Iowa Missouri Vly | $39.9M | $39.9M | $86.1M |
| 43 | Otto Schoitz Foundation Waterloo | $39.8M | $0 | $74.4M |
| 44 | Great River Health System INC W Burlington | $39.3M | $39.3M | $21.6M |
| 45 | Childserve Habilitation Center INC Johnston | $36.8M | $36.8M | $64.9M |
| 46 | Avera Holy Family Estherville | $35.9M | $35.9M | $68.4M |
| 47 | Community Health Centers of Southeastern Iowa INC W Burlington | $32.6M | $32.6M | $33.5M |
| 48 | Visiting Nurse Services of Iowa Des Moines | $30.4M | $30.4M | $29.6M |
| 49 | River Hills Community Health Center INC Ottumwa | $30.0M | $30.0M | $33.0M |
| 50 | Siouxland Pace INC Sioux City | $28.1M | $28.1M | $17.4M |