| 1 | Aids Action Coalition of Huntsville Huntsville | $33.3M | $33.1M | $20.2M |
| 2 | Aids Alabama INC Birmingham | $18.9M | $18.8M | $12.3M |
| 3 | United Ability INC Birmingham | $15.4M | $15.2M | $51.0M |
| 4 | Birmingham Aids Outreach INC Birmingham | $14.9M | $14.8M | $3.3M |
| 5 | Alabama Institute for Deaf and Blind Foundation INC Talladega | $8.6M | $2.5M | $19.2M |
| 6 | Health Services Center INC Anniston | $7.3M | $7.3M | $612K |
| 7 | Autauga-elmore Mr 310 Millbrook | $5.9M | $5.9M | $2.7M |
| 8 | The Bell Center for Early Intervention Programs Birmingham | $5.7M | $2.9M | $16.5M |
| 9 | Mitchells Place INC Birmingham | $5.6M | $5.4M | $3.2M |
| 10 | United Cerebral Palsy of West Alabama INC Northport | $4.7M | $4.7M | $1.6M |
| 11 | Aids Alabama South LLC Birmingham | $4.2M | $4.2M | $1.6M |
| 12 | Woolley Institute for Spoken- Language and Education Hoover | $3.3M | $3.1M | $4.4M |
| 13 | Alabama Kidney Foundation INC Hoover | $2.4M | $2.3M | $3.5M |
| 14 | Alabama Game Changers Hoover | $2.1M | $2.1M | $55K |
| 15 | Childrens Aid Foundation Birmingham | $1.7M | $367K | $8.3M |
| 16 | Hospice of Marshall County Foundation INC Albertville | $1.6M | $1.5M | $2.9M |
| 17 | Alabama Head Injury Foundation INC Hoover | $1.5M | $1.5M | $969K |
| 18 | United Cerebral Palsy of Ala Huntsville | $1.4M | $1.4M | $519K |
| 19 | Forge Survivorship Center Birmingham | $1.4M | $1.3M | $2.1M |
| 20 | Selma Air INC Selma | $1.4M | $1.4M | $284K |
| 21 | International Retinal Research Foundation INC Birmingham | $1.3M | $0 | $20.3M |
| 22 | Alabama Autism Assistance Program Birmingham | $1.3M | $1.3M | $242K |
| 23 | Respite for All Foundation Montgomery | $1.2M | $1.2M | $1.4M |
| 24 | Joy to Life Foundation Montgomery | $1.2M | $1.0M | $1.1M |
| 25 | Adys Army Birmingham | $1.2M | $1.2M | $1.1M |
| 26 | Arts N Autism INC Tuscaloosa | $913K | $897K | $1.4M |
| 27 | Alabama Chapter of the American Academy of Pediatrics Montgomery | $913K | $911K | $909K |
| 28 | Two Roads Autism Center INC Tuscaloosa | $814K | $800K | $40K |
| 29 | Alabama Lions Sight Association INC Birmingham | $771K | $771K | $1.6M |
| 30 | American Sports Medicine Institute INC Birmingham | $765K | $765K | $149K |
| 31 | The Anchor Cross Cancer Foundation Daphne | $675K | $465K | $1.4M |
| 32 | Montgomery Cancer Wellness Foundation Montgomery | $572K | $493K | $653K |
| 33 | Adoption and Foster Care Clinic Birmingham | $549K | $549K | $246K |
| 34 | Radiation Oncology Accelerated Research Vestavia | $523K | $356K | $18K |
| 35 | Ateam Ministries Homewood | $516K | $443K | $189K |
| 36 | Laura Crandall Brown Foundation Hoover | $501K | $501K | $231K |
| 37 | Autism Support of Alabama INC Birmingham | $484K | $416K | $707K |
| 38 | Kruzn for a Kure Foundation Muscle Shoals | $424K | $424K | $60K |
| 39 | Allo Hope Foundation Tuscaloosa | $396K | $396K | $147K |
| 40 | American Society of Ophthalmic Plastic & Reconstructive Surgery I Spanish Fort | $391K | $391K | $1.9M |
| 41 | Hemophilia and Bleeding Disordersof Alabama Eclectic | $368K | $335K | $52K |
| 42 | Central Alabama Alliance Resource & Advocacy Center Wetumpka | $330K | $330K | $27K |
| 43 | Childrens Oncology Camping Association International Dadeville | $299K | $299K | $224K |
| 44 | Tanner Foundation Birmingham | $286K | $265K | $159K |
| 45 | Hope Horses INC Cullman | $286K | $275K | $370K |
| 46 | Down Syndrome Alabama INC Hoover | $275K | $250K | $450K |
| 47 | Aubreighs Army Foundation 328 Mobile | $231K | $147K | $73K |
| 48 | Southern Assoc for Vascular Surgery INC Birmingham | $222K | $222K | $414K |
| 49 | Alabama Urology Network Montgomery | $187K | $187K | $132K |
| 50 | Miracle Mullen Downs Foundation Birmingham | $185K | $185K | $52K |