| 1 | Foundation to Combat Anti-semitism INC Foxborough | $144.4M | $0 | $211.1M |
| 2 | Institute for Healthcare Improvement Boston | $63.1M | $57.3M | $161.7M |
| 3 | International Institute of New England INC Boston | $37.4M | $33.5M | $28.6M |
| 4 | Accelerate Change INC Boston | $30.6M | $30.2M | $19.4M |
| 5 | New Commonwealth Racial Equity and Social Justice Fund INC Roxbury | $23.4M | $23.4M | $17.5M |
| 6 | Glbtq Legal Advocates & Defenders INC Boston | $15.6M | $10.8M | $11.9M |
| 7 | Pro-democracy Campaign Foxboro | $15.3M | $15.3M | $2.8M |
| 8 | Cultural Survival INC Cambridge | $10.5M | $10.5M | $17.3M |
| 9 | ACLU Foundation of Massachusetts INC Boston | $8.5M | $8.1M | $32.5M |
| 10 | One Fair Wage INC Cambridge | $7.4M | $7.4M | $3.5M |
| 11 | United for Democracy Foxborough | $6.8M | $6.8M | $2.7M |
| 12 | Massachusetts Immigrant and Refugee Advocacy Coalition INC Boston | $6.8M | $6.7M | $5.2M |
| 13 | Project on Predatory Student Lending INC Jamaica Plain | $5.9M | $5.9M | $5.0M |
| 14 | Justice Systems Partners South Easton | $5.5M | $5.5M | $2.4M |
| 15 | Muckrock Foundation Incorporated Boston | $5.3M | $5.3M | $4.0M |
| 16 | Turnout Activism INC Cambridge | $5.3M | $5.3M | $6.3M |
| 17 | Keshet INC Newton | $4.9M | $4.5M | $7.6M |
| 18 | The Massachusetts Association for Community Action INC Boston | $4.7M | $4.7M | $1.4M |
| 19 | A Healthier Democracy INC Boston | $4.5M | $4.5M | $1.8M |
| 20 | Prison Policy Initiative INC Northampton | $4.2M | $4.1M | $8.3M |
| 21 | Massachusetts Advocates for Children INC Boston | $3.4M | $3.4M | $3.3M |
| 22 | Disability Policy Consortium Boston | $2.2M | $2.2M | $1.2M |
| 23 | Neighbor to Neighbor Massachusetts Education Fund INC Worcester | $2.2M | $2.2M | $3.7M |
| 24 | New England Legal Foundation Boston | $2.1M | $1.3M | $1.3M |
| 25 | Tides for Reproductive Freedom Holyoke | $1.9M | $1.9M | $458K |
| 26 | Reproductive Equity Now Foundation INC Boston | $1.8M | $1.7M | $1.8M |
| 27 | Disability Rights Advocacy Fund INC Boston | $1.7M | $1.7M | $1.9M |
| 28 | Provide INC Boston | $1.6M | $1.6M | $2.1M |
| 29 | Massachusetts Senior Action Council INC Quincy | $1.6M | $1.6M | $2.1M |
| 30 | Redress Movement West Tisbury | $1.5M | $1.5M | $1.1M |
| 31 | Boston Casa INC Boston | $1.5M | $1.4M | $483K |
| 32 | Casa Project INC Worcester | $1.5M | $1.4M | $1.7M |
| 33 | Project Citizenship INC Boston | $1.4M | $1.4M | $1.9M |
| 34 | Cape Organization for Rights of the Disabled INC Hyannis | $1.3M | $1.3M | $1.4M |
| 35 | Community Labor United Incorporated Boston | $1.3M | $1.3M | $2.0M |
| 36 | Nonprofit Vote INC Somerville | $1.2M | $1.2M | $969K |
| 37 | Democracy Sentry Foxboro | $1.1M | $1.1M | $31K |
| 38 | Ally Coalition INC Cambridge | $1.0M | $1.0M | $1.0M |
| 39 | Proteus Action League Waltham | $1.0M | $1.0M | $1.9M |
| 40 | Friends of the Unborn Incorporated Quincy | $1.0M | $1.0M | $1.5M |
| 41 | More Than a Vote Lexington | $1.0M | $1.0M | $100 |
| 42 | Abortion Rights Fund of Western Massachusetts INC Amherst | $939K | $935K | $1.1M |
| 43 | Advocates for Informed Choice Sudbury | $924K | $824K | $756K |
| 44 | Give N Glow Wrentham | $853K | $853K | $729K |
| 45 | Leading Change Network INC Cambridge | $851K | $742K | $853K |
| 46 | Friends of Children INC Northampton | $801K | $794K | $311K |
| 47 | Foundation for Justice INC Easthampton | $751K | $0 | $649K |
| 48 | Out Metrowest INC Framingham | $724K | $709K | $440K |
| 49 | Massachusetts National Org for Women Foundation INC Boston | $723K | $720K | $314K |
| 50 | Massachusetts Women of Color Coalition INC Worcester | $685K | $685K | $507K |