| 1 | Philadelphia Orchestra Association Philadelphia | $175.8M | $84.4M | $234.5M |
| 2 | Barnes Foundation Philadelphia | $173.8M | $33.7M | $247.7M |
| 3 | Brandywine Conservancy & Museum of Art Chadds Ford | $157.6M | $42.7M | $208.7M |
| 4 | Philadelphia Museum of Art Philadelphia | $135.6M | $81.1M | $1.2B |
| 5 | Kimmel Center INC Philadelphia | $123.3M | $95.7M | $258.5M |
| 6 | Carnegie Institute Pittsburgh | $123.2M | $116.0M | $649.1M |
| 7 | Pittsburgh Symphony INC Pittsburgh | $106.0M | $55.2M | $187.6M |
| 8 | Pittsburgh Cultural Trust Pittsburgh | $89.7M | $83.8M | $243.4M |
| 9 | Whyy INC Philadelphia | $55.6M | $48.5M | $95.4M |
| 10 | Museum of the American Revolution Philadelphia | $55.2M | $33.1M | $171.9M |
| 11 | Mann Center for the Performing Arts Philadelphia | $54.9M | $53.8M | $76.3M |
| 12 | Franklin Institute Philadelphia | $53.2M | $51.2M | $226.4M |
| 13 | Kutztown University Foundation Kutztown | $46.8M | $19.4M | $83.4M |
| 14 | Curtis Institute of Music Philadelphia | $44.6M | $24.9M | $385.3M |
| 15 | National Constitution Center Philadelphia | $44.2M | $40.5M | $198.7M |
| 16 | Pennon Organization Harrisburg | $39.5M | $20.0M | $56.9M |
| 17 | The Fred Rogers Company Pittsburgh | $38.9M | $26.1M | $99.1M |
| 18 | American Philosophical Society Philadelphia | $38.1M | $20.4M | $310.2M |
| 19 | Artsquest Bethlehem | $36.3M | $34.2M | $57.4M |
| 20 | Northeastern Pennsylvania Educational Television Association Pittston | $34.5M | $7.1M | $37.1M |
| 21 | Independence Public Media of Philadelphia INC Philadelphia | $32.6M | $0 | $120.8M |
| 22 | Historical Society of Western Pennsylvania Pittsburgh | $27.7M | $22.0M | $77.4M |
| 23 | Pennsylvania Ballet Association Philadelphia | $27.4M | $26.7M | $58.9M |
| 24 | Walnut Street Theatre Corp. Philadelphia | $23.1M | $13.6M | $30.7M |
| 25 | Cp 2023 Philadelphia | $22.2M | $22.2M | $46.6M |
| 26 | Pittsburgh Ballet Theatre INC Pittsburgh | $22.0M | $12.8M | $29.9M |
| 27 | The Da Vinci Discovery Center of Science and Technology Allentown | $21.7M | $21.6M | $85.1M |
| 28 | Gettysburg Foundation Gettysburg | $21.5M | $16.9M | $104.6M |
| 29 | Lehigh Valley Public Telecommunications Corp. Bethlehem | $20.4M | $6.3M | $122.9M |
| 30 | Philadelphia Orchestra Association Trust -endowment Fund- Pittsburgh | $16.3M | $5.3M | $21.9M |
| 31 | Philadelphia Orchestra and Kimmel Center INC Philadelphia | $15.9M | $15.9M | $10.7M |
| 32 | Childrens Museum of Pittsburgh Pittsburgh | $15.0M | $12.1M | $38.2M |
| 33 | Settlement Music School of Philadelphia Philadelphia | $14.6M | $13.5M | $34.2M |
| 34 | Partners for Sacred Places INC Philadelphia | $14.5M | $4.9M | $18.6M |
| 35 | Philadelphia Mural Arts Advocates Philadelphia | $14.2M | $14.0M | $13.2M |
| 36 | Wqed Multimedia Pittsburgh | $13.7M | $13.2M | $26.7M |
| 37 | Lincoln Park Performing Arts Center Midland | $13.6M | $13.6M | $40.3M |
| 38 | Fulton Theatre Company Lancaster | $13.5M | $9.2M | $35.6M |
| 39 | Pittsburgh Opera INC Pittsburgh | $13.1M | $7.5M | $34.2M |
| 40 | Forman Arts Initiative INC Philadelphia | $13.0M | $0 | $86.4M |
| 41 | Center for Black Educator Development Elkins Park | $13.0M | $12.8M | $23.7M |
| 42 | Hoyt Center for the Arts New Castle | $12.9M | $5.2M | $32.5M |
| 43 | Heritage Conservancy Doylestown | $12.8M | $12.5M | $39.1M |
| 44 | Clay Studio Philadelphia | $12.3M | $6.9M | $28.9M |
| 45 | Please Touch Museum Philadelphia | $12.2M | $11.4M | $35.9M |
| 46 | Mary Louise Curtis Bok Foundation Philadelphia | $12.1M | $3.1M | $104.0M |
| 47 | Academy of Vocal Arts Philadelphia | $12.0M | $4.7M | $54.2M |
| 48 | Balletx Philadelphia | $12.0M | $11.6M | $14.0M |
| 49 | Woodmere Art Museum INC Philadelphia | $11.6M | $9.1M | $43.7M |
| 50 | Weitzman National Museum of American Jewish History Philadelphia | $11.4M | $10.3M | $31.6M |