| 1 | Humane Animal Partners INC Wilmington | $7.0M | $3.9M | $12.5M |
| 2 | Faithful Friends INC New Castle | $4.9M | $4.9M | $13.9M |
| 3 | First State Animal Center and SPCA INC Camden | $2.7M | $2.5M | $4.3M |
| 4 | Mi Angels Foundation Wilmington | $2.3M | $0 | $1.6M |
| 5 | Forgotten Cats INC Greenville | $2.3M | $2.3M | $3.5M |
| 6 | Tri-state Bird Rescue and Research INC Newark | $1.9M | $1.8M | $10.6M |
| 7 | Delaware Zoological Society INC Wilmington | $1.5M | $1.4M | $2.9M |
| 8 | Sunya INC Wilmington | $1.1M | $0 | $4.3M |
| 9 | Wildmon INC Lewes | $950K | $950K | $101K |
| 10 | Neenan Charitable Tr Wilmington | $800K | $0 | $1.4M |
| 11 | Delaware Humane Association Wilmington | $727K | $727K | $5.7M |
| 12 | Grass Roots Rescue Milton | $581K | $581K | $326K |
| 13 | Delaware Society for the Prevention of Cruelty to Animals Wilmington | $498K | $125K | $5.7M |
| 14 | Havanese Rescue INC Lewes | $485K | $485K | $1.9M |
| 15 | Animal Advocacy Africa Wilmington | $346K | $346K | $173K |
| 16 | Renees Rescues Incorporated Hockessin | $336K | $336K | $43K |
| 17 | Senior Dog Haven & Hospice INC Wilmington | $308K | $300K | $212K |
| 18 | National Humane Society Newark | $278K | $253K | $13K |
| 19 | Marine Education Research and Rehabilitation Institute INC Lewes | $226K | $205K | $486K |
| 20 | Veterinary Pharmacology Research Foundation Lewes | $217K | $217K | $337K |
| 21 | Changing Tomorrow Animal Rescue INC Dover | $198K | $198K | $45K |
| 22 | Animal People Alliance INC Dover | $197K | $197K | $230K |
| 23 | All Mutts Matter Foundation New Castle | $152K | $152K | $107K |
| 24 | Upstream Aquatic Institute INC Dover | $149K | $149K | $81K |
| 25 | Blind Dog Rescue Alliance Wilmington | $140K | $140K | $75K |
| 26 | Blue Heron Agility Dogs of Delaware Lewes | $131K | $59K | $95K |
| 27 | Southeastern Pa - Delaware House Rabbit Society L L C Wilmington | $122K | $115K | $8K |
| 28 | Andys Friends INC Wilmington | $119K | $119K | $80K |
| 29 | Sophias Grace Foundation Harbeson | $114K | $114K | $12K |
| 30 | Blue Ridge Bull Terrier Club Laurel | $99K | $95K | $43K |
| 31 | A World of Good Initiative INC Dover | $98K | $98K | $26K |
| 32 | Toller Rescue INC Lewes | $96K | $96K | $11K |
| 33 | Cheyla S Rescue Foundation Bear | $86K | $86K | $13K |
| 34 | Lewes Unleashed Association Lewes | $83K | $83K | $266K |
| 35 | Fur-ever Paws Dog Rescue INC Newark | $82K | $82K | $15K |
| 36 | Puppies and More Rescue INC Wilmington | $69K | $69K | $47K |
| 37 | Rescue for the Misunderstood Wilmington | $69K | $69K | $15K |
| 38 | Sonshine Equine INC Georgetown | $58K | $58K | $94K |
| 39 | Purr Project USA INC Milton | $57K | $57K | $64K |
| 40 | Summerwinds Stables INC Hartly | $52K | $52K | $298K |
| 41 | Tanners Endless Love INC Bear | $51K | $51K | $9K |
| 42 | South Coastal Delaware Dog Park Selbyville | $45K | $45K | $42K |
| 43 | Changing Fates Equine Rescue of Delaware INC Laurel | $43K | $43K | $411K |
| 44 | Katty Shack Feline Rescue Organization INC Houston | $20K | $20K | $1 |
| 45 | Navarro Foundation Millsboro | $1K | $0 | $153K |
| 46 | Good Nature Institute Newark | $1 | $0 | $29K |
| 47 | Haskins Family Foundation Wilmington | $1 | $0 | $121K |
| 48 | Al Clinton Operating Foundation Wilmington | $1 | $0 | $29K |
| 49 | Debra L Sipple Memorial INC Camden | $0 | $0 | $0 |
| 50 | Milton Catsnippers Milton | $0 | $0 | $0 |